{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T03:01:21Z","timestamp":1787022081054,"version":"build-2736575974"},"reference-count":16,"publisher":"Public Library of Science (PLoS)","issue":"4","license":[{"start":{"date-parts":[[2021,4,29]],"date-time":"2021-04-29T00:00:00Z","timestamp":1619654400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:p>The aim of this study was to evaluate the effectiveness of using biologically transparent illumination to detect the correct position of the nasogastric tube in surgical patients. This prospective observational study enrolled 102 patients undergoing general surgeries. In all cases, a nasogastric tube equipped with a biologically transparent illumination catheter was inserted after general anesthesia. The identification of biologically transparent light in the epigastric area either with or without finger pressure indicated that the tube had been successfully inserted into the stomach. X-ray examination was performed to ascertain the tube position and was compared with the findings of the biologically transparent illumination technique. Biologically transparent light was detected in 72 of the 102 patients. In all of these 72 patients, the position of the nasogastric tube in the stomach was confirmed by X-ray examination. The light was not detected in the other 30 patients; X-ray examination showed that the nasogastric tube was positioned in the stomach in 21 of these 30 patients but not in the other 9. The sensitivity and specificity of the illumination were 77.4% and 100%, respectively. The results suggest that biologically transparent illumination is a useful and safe technique for detecting the correct position of the nasogastric tube in surgical patients under general anesthesia. When the BT light cannot be identified, X-ray examination is mandatory to confirm the position of the nasogastric tube.<\/jats:p>","DOI":"10.1371\/journal.pone.0250258","type":"journal-article","created":{"date-parts":[[2021,4,29]],"date-time":"2021-04-29T13:41:00Z","timestamp":1619703660000},"page":"e0250258","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":15,"title":["Biologically transparent illumination is a safe, fast, and simple technique for detecting the correct position of the nasogastric tube in surgical patients under general anesthesia"],"prefix":"10.1371","volume":"16","author":[{"given":"Hirofumi","family":"Hirano","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanayo","family":"Masaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teppei","family":"Kamada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshie","family":"Taniguchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6543-6433","authenticated-orcid":true,"given":"Eiji","family":"Masaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2021,4,29]]},"reference":[{"key":"pone.0250258.ref001","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1001\/archinte.1989.00390010156022","article-title":"Pneumothorax due to nasogastric feeding tubes: Report of four cases, review of the literature, and recommendations for prevention","volume":"149","author":"R Roubenoff","year":"1989","journal-title":"Arch Intern Med"},{"key":"pone.0250258.ref002","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1007\/s001340050348","article-title":"Radiographic detection of intrabronchial malpositions of nasogastric tubes and subsequent complications in intensive care unit patients","volume":"23","author":"AA Bankier","year":"1997","journal-title":"Intensive Care Med"},{"key":"pone.0250258.ref003","doi-asserted-by":"crossref","first-page":"2055","DOI":"10.1097\/00003246-199712000-00026","article-title":"Nonradiographic assessment of enteral feeding tube position","volume":"25","author":"AM Harrison","year":"1997","journal-title":"Crit Care Med"},{"key":"pone.0250258.ref004","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/j.ijnurstu.2016.06.011","article-title":"Confirming nasogastric tube placement: Is the colorimeter as sensitive and specific as X-ray? 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