{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,28]],"date-time":"2025-12-28T10:52:19Z","timestamp":1766919139610,"version":"3.37.3"},"reference-count":17,"publisher":"Public Library of Science (PLoS)","issue":"4","license":[{"start":{"date-parts":[[2021,4,30]],"date-time":"2021-04-30T00:00:00Z","timestamp":1619740800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003661","name":"Korea Institute for Advancement of Technology","doi-asserted-by":"publisher","award":["P0008805"],"award-info":[{"award-number":["P0008805"]}],"id":[{"id":"10.13039\/501100003661","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\">\n<jats:title>Purpose<\/jats:title>\n<jats:p>To evaluate the osseous anatomy of the proximal femur extracted from a 3D-MRI volumetric interpolated breath-hold (VIBE) sequence using either a Dixon or water excitation (WE) fat suppression method, and to measure the overall difference using CT as a reference standard.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec002\">\n<jats:title>Material and methods<\/jats:title>\n<jats:p>This retrospective study reviewed imaging of adult patients with hip pain who underwent 3D hip MRI and CT. A semi-automatically segmented CT model served as the reference standard, and MRI segmentation was performed manually for each unilateral hip joint. The differences between Dixon-VIBE-3D-MRI vs. CT, and WE-VIBE-3D-MRI vs. CT, were measured. Equivalence tests between Dixon-VIBE and WE-VIBE models were performed with a threshold of 0.1 mm. Bland\u2013Altman plots and Lin\u2019s concordance-correlation coefficient were used to analyze the agreement between WE and Dixon sequences. Subgroup analyses were performed for the femoral head\/neck, intertrochanteric, and femoral shaft areas.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec003\">\n<jats:title>Results<\/jats:title>\n<jats:p>The mean and maximum differences between Dixon-VIBE-3D-MRI vs. CT were 0.2917 and 3.4908 mm, respectively, whereas for WE-VIBE-3D-MRI vs. CT they were 0.3162 and 3.1599 mm. The mean differences of the WE and Dixon methods were equivalent (<jats:italic>P<\/jats:italic> = 0.0292). However, the maximum difference was not equivalent between the two methods and it was higher in WE method. Lin\u2019s concordance-correlation coefficient showed poor agreement between Dixon and WE methods. The mean differences between the CT and 3D-MRI models were significantly higher in the femoral shaft area (<jats:italic>P<\/jats:italic> = 0.0004 for WE and <jats:italic>P<\/jats:italic> = 0.0015 for Dixon) than in the other areas. The maximum difference was greatest in the intertrochanteric area for both techniques.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec004\">\n<jats:title>Conclusion<\/jats:title>\n<jats:p>The difference between 3D-MR and CT models were acceptable with a maximal difference below 3.5mm. WE and Dixon fat suppression methods were equivalent. The mean difference was highest at the femoral shaft area, which was off-center from the magnetization field.<\/jats:p>\n<\/jats:sec>","DOI":"10.1371\/journal.pone.0250334","type":"journal-article","created":{"date-parts":[[2021,4,30]],"date-time":"2021-04-30T17:38:44Z","timestamp":1619804324000},"page":"e0250334","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":4,"title":["Differences between 3D isovoxel fat suppression VIBE MRI and CT models of proximal femur osseous anatomy: A preliminary study for bone tumor resection planning"],"prefix":"10.1371","volume":"16","author":[{"given":"Choong Guen","family":"Chee","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5597-8143","authenticated-orcid":true,"given":"Hye Won","family":"Chung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wanlim","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Min A.","family":"Yoon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"So Myoung","family":"Shin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guk Bae","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2021,4,30]]},"reference":[{"key":"pone.0250334.ref001","doi-asserted-by":"crossref","first-page":"20160407","DOI":"10.1259\/dmfr.20160407","article-title":"\"Black Bone\" MRI: a novel imaging technique for 3D printing","volume":"46","author":"KA Eley","year":"2017","journal-title":"Dentomaxillofac Radiol"},{"key":"pone.0250334.ref002","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1259\/bjr\/95110289","article-title":"\"Black bone\" MRI: a partial flip angle technique for radiation reduction in craniofacial imaging","volume":"85","author":"KA Eley","year":"2012","journal-title":"Br J Radiol"},{"key":"pone.0250334.ref003","doi-asserted-by":"crossref","first-page":"1457","DOI":"10.1259\/bjr\/16830245","article-title":"\"Black bone\" MRI: a potential alternative to CT when imaging the head and neck: report of eight clinical cases and review of the Oxford experience","volume":"85","author":"KA Eley","year":"2012","journal-title":"Br J Radiol"},{"key":"pone.0250334.ref004","doi-asserted-by":"crossref","first-page":"2417","DOI":"10.1007\/s00330-014-3286-7","article-title":"\"Black Bone\" MRI: a potential alternative to CT with three-dimensional reconstruction of the craniofacial skeleton in the diagnosis of craniosynostosis","volume":"24","author":"KA Eley","year":"2014","journal-title":"Eur Radiol"},{"key":"pone.0250334.ref005","doi-asserted-by":"crossref","first-page":"20130236","DOI":"10.1259\/dmfr.20130236","article-title":"\"Black Bone\" MRI: a potential non-ionizing method for three-dimensional cephalometric analysis\u2014a preliminary feasibility study","volume":"42","author":"KA Eley","year":"2013","journal-title":"Dentomaxillofac Radiol"},{"key":"pone.0250334.ref006","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1007\/s00256-018-3049-7","article-title":"3D-MRI versus 3D-CT in the evaluation of osseous anatomy in femoroacetabular impingement using Dixon 3D FLASH sequence","volume":"48","author":"M Samim","year":"2019","journal-title":"Skeletal Radiol"},{"key":"pone.0250334.ref007","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1007\/s00256-013-1774-5","article-title":"Use of 3D MR reconstructions in the evaluation of glenoid bone loss: a clinical study","volume":"43","author":"S 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Wong","year":"2015","journal-title":"Comput Aided Surg"},{"key":"pone.0250334.ref011","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1007\/s11548-015-1250-x","article-title":"Patient-specific instrument can achieve same accuracy with less resection time than navigation assistance in periacetabular pelvic tumor surgery: a cadaveric study","volume":"11","author":"KC Wong","year":"2016","journal-title":"Int J Comput Assist Radiol Surg"},{"key":"pone.0250334.ref012","doi-asserted-by":"crossref","first-page":"1902","DOI":"10.1007\/s00586-016-4871-z","article-title":"One-step reconstruction with a 3D-printed, custom-made prosthesis after total en bloc sacrectomy: a technical note","volume":"26","author":"R Wei","year":"2017","journal-title":"Eur Spine J"},{"key":"pone.0250334.ref013","doi-asserted-by":"crossref","first-page":"898","DOI":"10.1002\/jso.25236","article-title":"Bone tumor resection guide using three-dimensional printing for limb salvage surgery","volume":"118","author":"JW Park","year":"2018","journal-title":"J Surg Oncol"},{"key":"pone.0250334.ref014","doi-asserted-by":"crossref","first-page":"28","DOI":"10.3390\/jimaging3030028","article-title":"Assessment of geometric distortion in six clinical scanners using a 3D-printed grid phantom","volume":"3","author":"M Jafar","year":"2017","journal-title":"J Imaging"},{"key":"pone.0250334.ref015","first-page":"247","volume":"56","author":"B Li","year":"1997","journal-title":"Mechanical and material properties of the subchondral bone plate from the femoral head of patients with osteoarthritis or osteoporosis"},{"key":"pone.0250334.ref016","first-page":"23","article-title":"imaging i","volume":"99","author":"T Kirchgesner","year":"2018","journal-title":"Fat suppression at three-dimensional T1-weighted MR imaging of the hands: Dixon method versus CHESS 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J.","family":"Cray","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2021,4,30]]},"references-count":17,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2021,4,30]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0250334","relation":{},"ISSN":["1932-6203"],"issn-type":[{"type":"electronic","value":"1932-6203"}],"subject":[],"published":{"date-parts":[[2021,4,30]]}}}