{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T19:53:38Z","timestamp":1780084418727,"version":"3.54.0"},"reference-count":35,"publisher":"Public Library of Science (PLoS)","issue":"5","license":[{"start":{"date-parts":[[2021,5,3]],"date-time":"2021-05-03T00:00:00Z","timestamp":1620000000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"\nBackground<\/jats:title>\nHigh-degree atrioventricular block (HAVB) is a prognostic factor for survival in patients with inferior ST-segment elevation myocardial infarction (STEMI). However, there is little information about factors associated with temporary pacing (TP). The aim of this study was to find factors associated with TP in patients with inferior STEMI.<\/jats:p>\n<\/jats:sec>\n\nMethods<\/jats:title>\nWe included 232 inferior STEMI patients, and divided those into the TP group (n = 46) and the non-TP group (n = 186). Factors associated with TP were retrospectively investigated using multivariate logistic regression model.<\/jats:p>\n<\/jats:sec>\n\nResults<\/jats:title>\nThe incidence of right ventricular (RV) infarction was significantly higher in the TP group (19.6%) than in the non-TP group (7.5%) (p = 0.024), but the incidence of in-hospital death was similar between the 2 groups (4.3% vs. 4.8%, p = 1.000). Long-term major adverse cardiovascular events (MACE), which were defined as a composite of all-cause death, non-fatal myocardial infarction (MI), target vessel revascularization (TVR) and readmission for heart failure, were not different between the 2 groups (p = 0.100). In the multivariate logistic regression analysis, statin at admission [odds ratio (OR) 0.230, 95% confidence interval (CI) 0.062\u20130.860, p = 0.029], HAVB at admission (OR 9.950, 95% CI 4.099\u201324.152, p<0.001), and TIMI-thrombus grade \u22653 (OR 10.762, 95% CI 1.385\u201383.635, p = 0.023) were significantly associated with TP.<\/jats:p>\n<\/jats:sec>\n\nConclusion<\/jats:title>\nStatin at admission, HAVB at admission, and TIMI-thrombus grade \u22653 were associated with TP in patients with inferior STEMI. Although the patients with TP had the higher incidence of RV infarction, the incidence of in-hospital death and long-term MACE was not different between patients with TP and those without.<\/jats:p>\n<\/jats:sec>","DOI":"10.1371\/journal.pone.0251124","type":"journal-article","created":{"date-parts":[[2021,5,3]],"date-time":"2021-05-03T17:43:36Z","timestamp":1620063816000},"page":"e0251124","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":7,"title":["Factors associated with temporary pacing insertion in patients with inferior ST-segment elevation myocardial infarction"],"prefix":"10.1371","volume":"16","author":[{"given":"Tomonobu","family":"Yanase","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3566-0394","authenticated-orcid":true,"given":"Kenichi","family":"Sakakura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroyuki","family":"Jinnouchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yousuke","family":"Taniguchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kei","family":"Yamamoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takunori","family":"Tsukui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masaru","family":"Seguchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Wada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4901-3502","authenticated-orcid":true,"given":"Hideo","family":"Fujita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2021,5,3]]},"reference":[{"key":"pone.0251124.ref001","first-page":"699","article-title":"French Registry on Acute ST-elevation and non ST-elevation Myocardial Infarction 2010","volume":"98","author":"M Hanssen","year":"2012","journal-title":"FAST-MI 2010. Heart"},{"key":"pone.0251124.ref002","doi-asserted-by":"crossref","first-page":"8104939","DOI":"10.1155\/2020\/8104939","article-title":"In-Stent Restenosis and a Drug-Coated Balloon: Insights from a Clinical Therapeutic Strategy on Coronary Artery Diseases","volume":"2020","author":"DM Zhang","year":"2020","journal-title":"Cardiol Res Pract"},{"key":"pone.0251124.ref003","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.ahj.2008.03.011","article-title":"Thirty-year trends (1975\u20132005) in the magnitude and hospital death rates associated with complete heart block in patients with acute myocardial infarction: a population-based perspective","volume":"156","author":"HL Nguyen","year":"2008","journal-title":"Am Heart J"},{"key":"pone.0251124.ref004","doi-asserted-by":"crossref","first-page":"1639","DOI":"10.1093\/europace\/eus161","article-title":"High-degree atrioventricular block complicating ST-segment elevation myocardial infarction in the era of primary percutaneous coronary intervention","volume":"14","author":"UJ Gang","year":"2012","journal-title":"Europace"},{"key":"pone.0251124.ref005","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3109\/17482941.2013.869343","article-title":"Prognostic implications of atrio-ventricular block in patients undergoing primary coronary angioplasty in the stent era","volume":"16","author":"S G\u00f3mez-Talavera","year":"2014","journal-title":"Acute Card Care"},{"key":"pone.0251124.ref006","doi-asserted-by":"crossref","first-page":"1658","DOI":"10.1016\/j.amjcard.2014.08.038","article-title":"Influence of second- and third-degree heart block on 30-day outcome following acute myocardial infarction in the drug-eluting stent era","volume":"114","author":"HL Kim","year":"2014","journal-title":"Am J Cardiol"},{"key":"pone.0251124.ref007","first-page":"2027","article-title":"Primary percutaneous coronary intervention ameliorates complete atrioventricular block complicating acute inferior myocardial infarction","volume":"9","author":"SN Lee","year":"2014","journal-title":"Clin Interv Aging"},{"key":"pone.0251124.ref008","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1016\/j.jacc.2018.10.045","article-title":"Impact of Physiologic Pacing Versus Right Ventricular Pacing Among Patients With Left Ventricular Ejection Fraction Greater Than 35%: A Systematic Review for the 2018 ACC\/AHA\/HRS Guideline on the Evaluation and Management of Patients With Bradycardia and Cardiac Conduction Delay: A Report of the American College of Cardiology\/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society","volume":"74","author":"DJ Slotwiner","year":"2019","journal-title":"J Am Coll Cardiol"},{"key":"pone.0251124.ref009","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1001\/jama.286.6.700","article-title":"Complications of femoral and subclavian venous catheterization in critically ill patients: a randomized controlled trial","volume":"286","author":"J Merrer","year":"2001","journal-title":"Jama"},{"key":"pone.0251124.ref010","doi-asserted-by":"crossref","first-page":"287","DOI":"10.2147\/CIA.S99698","article-title":"Periprocedural temporary pacing in primary percutaneous coronary intervention for patients with acute inferior myocardial infarction","volume":"11","author":"YM Hwang","year":"2016","journal-title":"Clin Interv Aging"},{"key":"pone.0251124.ref011","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1007\/s12471-019-01307-x","article-title":"A comprehensive scoping review on transvenous temporary pacing therapy","volume":"27","author":"FVY Tjong","year":"2019","journal-title":"Neth Heart J"},{"key":"pone.0251124.ref012","first-page":"1","article-title":"Temporary Transvenous Cardiac Pacing in Patients With Acute Myocardial Infarction Predicts Increased Mortality","volume":"3","author":"Y Yaqub","year":"2012","journal-title":"Cardiol Res"},{"key":"pone.0251124.ref013","doi-asserted-by":"crossref","first-page":"2231","DOI":"10.1016\/j.jacc.2018.08.1038","article-title":"Fourth Universal Definition of Myocardial Infarction (2018)","volume":"72","author":"K Thygesen","year":"2018","journal-title":"J Am Coll Cardiol"},{"key":"pone.0251124.ref014","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1007\/s00380-017-1089-x","article-title":"Determinants of short and long door-to-balloon time in current primary percutaneous coronary interventions","volume":"33","author":"T Tsukui","year":"2018","journal-title":"Heart Vessels"},{"key":"pone.0251124.ref015","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1067\/mhj.2001.112404","article-title":"Rationale and design of the GRACE (Global Registry of Acute Coronary Events) Project: a multinational registry of patients hospitalized with acute coronary syndromes","volume":"141","author":"GRACE investigators","year":"2001","journal-title":"Am Heart J"},{"key":"pone.0251124.ref016","first-page":"691","article-title":"Sick sinus syndrome: a review","volume":"87","author":"M Semelka","year":"2013","journal-title":"Am Fam Physician"},{"key":"pone.0251124.ref017","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1016\/0002-8703(92)91012-P","article-title":"Normal sinus heart rate: sinus tachycardia and sinus bradycardia redefined","volume":"124","author":"DH Spodick","year":"1992","journal-title":"Am Heart J"},{"key":"pone.0251124.ref018","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.jjcc.2019.06.008","article-title":"Association of slow flow with clinical factors in intravascular ultrasound-guided percutaneous coronary intervention for patients with left main trunk-acute myocardial infarction","volume":"75","author":"K Yamamoto","year":"2020","journal-title":"J Cardiol"},{"key":"pone.0251124.ref019","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1536\/ihj.20-165","article-title":"Determinants of In-Hospital Death Among the Very Elderly with Acute Myocardial Infarction","volume":"61","author":"M Seguchi","year":"2020","journal-title":"Int Heart J"},{"key":"pone.0251124.ref020","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1536\/ihj.18-515","article-title":"The Comparison of Clinical Outcomes Between Inferior ST-Elevation Myocardial Infarction with Right Ventricular Infarction Versus Without Right Ventricular Infarction","volume":"60","author":"M Noguchi","year":"2019","journal-title":"Int Heart J"},{"key":"pone.0251124.ref021","doi-asserted-by":"crossref","first-page":"982","DOI":"10.1053\/j.ajkd.2008.12.034","article-title":"Revised equations for estimated GFR from serum creatinine in Japan","volume":"53","author":"S Matsuo","year":"2009","journal-title":"Am J Kidney Dis"},{"key":"pone.0251124.ref022","doi-asserted-by":"crossref","first-page":"2550","DOI":"10.1161\/01.CIR.103.21.2550","article-title":"Combination therapy with abciximab reduces angiographically evident thrombus in acute myocardial infarction: a TIMI 14 substudy","volume":"103","author":"CM Gibson","year":"2001","journal-title":"Circulation"},{"key":"pone.0251124.ref023","first-page":"40","article-title":"Pattern of coronary arterial distribution and its relation to coronary artery diameter","volume":"17","author":"ZA Kaimkhani","year":"2005","journal-title":"J Ayub Med Coll Abbottabad"},{"key":"pone.0251124.ref024","article-title":"Comparing the clinical and prognostic impact of proximal versus nonproximal lesions in dominant right coronary artery ST-elevation myocardial infarction","author":"G Femia","year":"2020","journal-title":"Catheter Cardiovasc Interv"},{"key":"pone.0251124.ref025","doi-asserted-by":"crossref","first-page":"1134","DOI":"10.1016\/S0002-9149(97)00628-0","article-title":"Admission clinical and electrocardiographic characteristics predicting in-hospital development of high-degree atrioventricular block in inferior wall acute myocardial infarction","volume":"80","author":"Y Birnbaum","year":"1997","journal-title":"Am J Cardiol"},{"key":"pone.0251124.ref026","doi-asserted-by":"crossref","first-page":"1622","DOI":"10.1016\/0002-8703(93)90750-4","article-title":"Complete atrioventricular block complicating inferior acute wall myocardial infarction: short- and long-term prognosis","volume":"125","author":"S Behar","year":"1993","journal-title":"Am Heart J"},{"key":"pone.0251124.ref027","first-page":"956","article-title":"Predictors of inhospital outcome after acute inferior wall myocardial infarction","volume":"50","author":"MH Jim","year":"2009","journal-title":"Singapore Med J"},{"key":"pone.0251124.ref028","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1136\/heartjnl-2015-308260","article-title":"High-degree atrioventricular block complicating ST segment elevation myocardial infarction in the contemporary era","volume":"102","author":"V Auffret","year":"2016","journal-title":"Heart"},{"key":"pone.0251124.ref029","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1177\/1076029613483169","article-title":"Determinants of angiographic thrombus burden in patients with ST-segment elevation myocardial infarction","volume":"20","author":"IH Tanboga","year":"2014","journal-title":"Clin Appl Thromb Hemost"},{"key":"pone.0251124.ref030","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/j.jacc.2009.04.033","article-title":"Effect of intensive statin therapy on regression of coronary atherosclerosis in patients with acute coronary syndrome: a multicenter randomized trial evaluated by volumetric intravascular ultrasound using pitavastatin versus atorvastatin (JAPAN-ACS [Japan assessment of pitavastatin and atorvastatin in acute coronary syndrome] study)","volume":"54","author":"T Hiro","year":"2009","journal-title":"J Am Coll Cardiol"},{"key":"pone.0251124.ref031","doi-asserted-by":"crossref","first-page":"1246","DOI":"10.1016\/j.amjcard.2013.01.265","article-title":"Evaluation of serial changes in tissue characteristics during statin-induced plaque regression using virtual histology-intravascular ultrasound studies","volume":"111","author":"I Taguchi","year":"2013","journal-title":"Am J Cardiol"},{"key":"pone.0251124.ref032","doi-asserted-by":"crossref","first-page":"1466","DOI":"10.1253\/circj.CJ-08-1051","article-title":"Early effect of lipid-lowering therapy with pitavastatin on regression of coronary atherosclerotic plaque. Comparison with atorvastatin","volume":"73","author":"T Toi","year":"2009","journal-title":"Circ J"},{"key":"pone.0251124.ref033","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1016\/j.amjcard.2013.11.054","article-title":"Effect of chronic statin treatment on vascular remodeling determined by intravascular ultrasound in patients with acute myocardial infarction","volume":"113","author":"H Jinnouchi","year":"2014","journal-title":"Am J Cardiol"},{"key":"pone.0251124.ref034","doi-asserted-by":"crossref","first-page":"1545","DOI":"10.1016\/j.jcin.2018.03.021","article-title":"A Randomized Study of Distal Filter Protection Versus Conventional Treatment During Percutaneous Coronary Intervention in Patients With Attenuated Plaque Identified by Intravascular Ultrasound","volume":"11","author":"K Hibi","year":"2018","journal-title":"JACC Cardiovasc Interv"},{"key":"pone.0251124.ref035","doi-asserted-by":"crossref","first-page":"e362","DOI":"10.1161\/CIR.0b013e3182742c84","article-title":"2013 ACCF\/AHA guideline for the management of ST-elevation myocardial infarction: a report of the American College of Cardiology Foundation\/American Heart Association Task Force on Practice Guidelines","volume":"127","author":"PT O\u2019Gara","year":"2013","journal-title":"Circulation"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0251124","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,3]],"date-time":"2021-05-03T17:44:28Z","timestamp":1620063868000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0251124"}},"subtitle":[],"editor":[{"given":"Corstiaan","family":"den Uil","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2021,5,3]]},"references-count":35,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2021,5,3]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0251124","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,5,3]]}}}