{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T22:47:57Z","timestamp":1792277277592,"version":"4.4.0"},"reference-count":24,"publisher":"Public Library of Science (PLoS)","issue":"6","license":[{"start":{"date-parts":[[2021,6,4]],"date-time":"2021-06-04T00:00:00Z","timestamp":1622764800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\"><jats:title>Background<\/jats:title><jats:p>Regional analgesia is worth performing in the multimodal postoperative management of hip fracture (HF) because it reduces hospital morbidity and mortality. The aim of this study is to compare the efficacy and side effects of the recently described \u201cPericapsular Nerve Group (PENG) Block\u201d with those of the femoral block, which is considered the standard of care for postoperative pain control after femoral neck fracture.<\/jats:p><\/jats:sec><jats:sec id=\"sec002\"><jats:title>Materials and methods<\/jats:title><jats:p>We conducted a comparative observational study at a university hospital (Saint Antoine Hospital, Sorbonne University, Paris, France), where the PENG block was introduced in August 2019. We include all patients from June to October 2019, who were coming for femoral neck fractures and who had an analgesic femoral block or PENG block before their surgery. The primary outcome was the comparison of cumulative postoperative morphine consumption 48 hours after surgery.<\/jats:p><\/jats:sec><jats:sec id=\"sec003\"><jats:title>Results<\/jats:title><jats:p>Demographics, medical charts, and perioperative data of 42 patients were reviewed: 21 patients before (Femoral group) and 21 patients after the introduction of PENG block (PENG group) in clinical practice. Thirteen total hip arthroplasties (THA) and eight hemi arthroplasties (HA) were included in each group. Demographics were also comparable. The median, postoperative, morphine equivalent consumption at 48 hours was 10 [0\u201320] mg and 20 [0\u201350] mg in Femoral and PENG groups respectively (p = 0.458). No statistically significant differences were found in postoperative pain intensity, time to ambulation, incidence of morphine-related side effects, or length of hospital stay. The postoperative muscle strength of the quadriceps was greater in the PENG group than in the Femoral group (5\/5 vs. 2\/5, p = 0.001).<\/jats:p><\/jats:sec><jats:sec id=\"sec004\"><jats:title>Conclusion<\/jats:title><jats:p>In the management of hip fractures, PENG block is not associated in our study with a significant change in postoperative morphine consumption, compared to femoral block. However, it does significantly improve the immediate mobility of the operated limb, making it appropriate for inclusion in enhanced recovery programs after surgery.<\/jats:p><\/jats:sec>","DOI":"10.1371\/journal.pone.0252716","type":"journal-article","created":{"date-parts":[[2021,6,4]],"date-time":"2021-06-04T17:48:15Z","timestamp":1622828895000},"page":"e0252716","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":58,"title":["Comparison between femoral block and PENG block in femoral neck fractures: A cohort study"],"prefix":"10.1371","volume":"16","author":[{"given":"C\u00e9line","family":"Allard","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6326-3834","authenticated-orcid":true,"given":"Emmanuel","family":"Pardo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christophe","family":"de la Jonqui\u00e8re","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Wyniecki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Soulier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6513-4937","authenticated-orcid":true,"given":"Annibal","family":"Faddoul","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eileen S.","family":"Tsai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francis","family":"Bonnet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7061-5594","authenticated-orcid":true,"given":"Franck","family":"Verdonk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2021,6,4]]},"reference":[{"issue":"14","key":"pone.0252716.ref001","doi-asserted-by":"crossref","first-page":"1573","DOI":"10.1001\/jama.2009.1462","article-title":"Incidence and Mortality of Hip Fractures in the United States","volume":"302","author":"CA Brauer","year":"2009","journal-title":"JAMA"},{"issue":"1","key":"pone.0252716.ref002","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1177\/2151458510378105","article-title":"The 1-Year Mortality of Patients Treated in a Hip Fracture Program for Elders","volume":"1","author":"S Schnell","year":"2010","journal-title":"Geriatr Orthop Surg Rehabil"},{"issue":"4","key":"pone.0252716.ref003","doi-asserted-by":"crossref","first-page":"298","DOI":"10.5144\/0256-4947.2020.298","article-title":"One-year postoperative mortality rate among the elderly with hip fractures at a single tertiary care center","volume":"40","author":"KA Alsheikh","year":"2020","journal-title":"Ann Saudi Med"},{"issue":"7529","key":"pone.0252716.ref004","doi-asserted-by":"crossref","first-page":"1374","DOI":"10.1136\/bmj.38643.663843.55","article-title":"Effect of comorbidities and postoperative complications on mortality after hip fracture in elderly people: prospective observational cohort study","volume":"331","author":"JJW Roche","year":"2005","journal-title":"BMJ"},{"issue":"7369","key":"pone.0252716.ref005","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1136\/bmj.325.7369.868","article-title":"Mortality after admission to hospital with fractured neck of femur: database study","volume":"325","author":"MJ Goldacre","year":"2002","journal-title":"BMJ"},{"issue":"5","key":"pone.0252716.ref006","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1136\/qshc.2005.017095","article-title":"Reduced morbidity for elderly patients with a hip fracture after implementation of a perioperative evidence-based clinical pathway","volume":"15","author":"LA Beaupre","year":"2006","journal-title":"Qual Saf Health Care"},{"key":"pone.0252716.ref007","article-title":"Peripheral nerve blocks for hip fractures. Cochrane Anaesthesia Group, \u00e9diteur","author":"J Guay","year":"2017","journal-title":"Cochrane Database Syst Rev"},{"issue":"8","key":"pone.0252716.ref008","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1016\/j.jclinane.2015.07.001","article-title":"Local anesthetic injection deep to the fascia iliaca at the level of the inguinal ligament: the pattern of distribution and effects on the obturator nerve","volume":"27","author":"JD Swenson","year":"2015","journal-title":"J Clin Anesth"},{"issue":"1","key":"pone.0252716.ref009","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1186\/s12245-018-0173-z","article-title":"Emergency physician-performed ultrasound-guided nerve blocks in proximal femoral fractures provide safe and effective pain relief: a prospective observational study in The Netherlands","volume":"11","author":"R Ketelaars","year":"2018","journal-title":"Int J Emerg Med. d\u00e9c"},{"key":"pone.0252716.ref010","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/AAP.0000000000000701","article-title":"Anatomic Study of Innervation of the Anterior Hip Capsule: Implication for Image-Guided Intervention","author":"AJ Short","year":"2017","journal-title":"Reg Anesth Pain Med"},{"key":"pone.0252716.ref011","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/AAP.0000000000000847","article-title":"Pericapsular Nerve Group (PENG) Block for Hip Fracture","author":"L Gir\u00f3n-Arango","year":"2018","journal-title":"Reg Anesth Pain Med"},{"key":"pone.0252716.ref012","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.jclinane.2019.06.021","article-title":"Pericapsular nerve group (PENG) block for surgical anesthesia of medial thigh","volume":"59","author":"A Ahiskalioglu","year":"2020","journal-title":"J Clin Anesth"},{"issue":"5","key":"pone.0252716.ref013","article-title":"A Retrospective Case Series of Pericapsular Nerve Group (PENG) Block for Primary Versus Revision Total Hip Arthroplasty Analgesia","volume":"12","author":"P Kukreja","journal-title":"Cureus"},{"key":"pone.0252716.ref014","first-page":"60","article-title":"block for hip surgery","volume":"51","author":"H Ueshima","year":"2018","journal-title":"J Clin Anesth"},{"issue":"9","key":"pone.0252716.ref015","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1111\/anae.12321","article-title":"A comparison of pre-operative nerve stimulator-guided femoral nerve block and fascia iliaca compartment block in patients with a femoral neck fracture","volume":"68","author":"B Newman","year":"2013","journal-title":"Anaesthesia"},{"issue":"1","key":"pone.0252716.ref016","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1017\/cem.2015.75","article-title":"Regional Nerve Blocks For Hip and Femoral Neck Fractures in the Emergency Department: A Systematic Review","volume":"18","author":"B Ritcey","year":"2016","journal-title":"CJEM"},{"key":"pone.0252716.ref017","volume-title":"Aids to the examination of the peripheral nervous system","author":"Medical Research Council","year":"1976"},{"key":"pone.0252716.ref018","first-page":"11","author":"GM Orosz","year":"2006","journal-title":"The Timing of Surgery for Hip Fracture and its Effects on Outcomes"},{"issue":"38 Suppl 1","key":"pone.0252716.ref019","doi-asserted-by":"crossref","first-page":"S67","DOI":"10.1097\/EJA.0000000000001271","article-title":"Impact of delayed patient flow on surgical outcomes after hip fracture: An observational study","author":"I Da Costa","year":"2021","journal-title":"Eur J Anaesthesiol"},{"key":"pone.0252716.ref020","unstructured":"RCP London. National Hip Fracture Database annual report 2016 [Internet]. 2016. Disponible sur: https:\/\/www.rcplondon.ac.uk\/projects\/outputs\/national-hip-fracture-database-annual-report-2016"},{"issue":"7","key":"pone.0252716.ref021","doi-asserted-by":"crossref","first-page":"1542","DOI":"10.1016\/j.injury.2017.04.043","article-title":"Femoral nerve block in a representative sample of elderly people with hip fracture: A randomised controlled trial","volume":"48","author":"A Unneby","year":"2017","journal-title":"Injury"},{"issue":"1","key":"pone.0252716.ref022","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1186\/s12877-017-0446-z","article-title":"Drug-based pain management for people with dementia after hip or pelvic fractures: a systematic review","volume":"17","author":"K Moschinski","year":"2017","journal-title":"BMC Geriatr"},{"issue":"2","key":"pone.0252716.ref023","doi-asserted-by":"crossref","first-page":"242","DOI":"10.4103\/joacp.JOACP_172_17","article-title":"Ultrasound-guided adductor canal block versus femoral nerve block for arthroscopic anterior cruciate ligament repair under general anesthesia","volume":"34","author":"PS Ghodki","year":"2018","journal-title":"J Anaesthesiol Clin Pharmacol"},{"key":"pone.0252716.ref024","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.jclinane.2019.07.006","article-title":"Gray zone of pericapsular nerve group (PENG) block","volume":"58","author":"T Mistry","year":"2019","journal-title":"J Clin Anesth"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0252716","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,12,29]],"date-time":"2022-12-29T23:02:00Z","timestamp":1672354920000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0252716"}},"subtitle":[],"editor":[{"given":"Robert Jeenchen","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2021,6,4]]},"references-count":24,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2021,6,4]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0252716","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,6,4]]}}}