{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T07:55:05Z","timestamp":1770882905738,"version":"3.50.1"},"reference-count":34,"publisher":"Public Library of Science (PLoS)","issue":"7","license":[{"start":{"date-parts":[[2021,7,2]],"date-time":"2021-07-02T00:00:00Z","timestamp":1625184000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"JSPS KAKENHI","award":["21K17501"],"award-info":[{"award-number":["21K17501"]}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\">\n<jats:title>Background<\/jats:title>\n<jats:p>Limitation of instrumental activity of daily living (IADL) is independently associated with an adverse prognosis in older heart failure (HF) patients.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec002\">\n<jats:title>Aims<\/jats:title>\n<jats:p>This multicenter study aims to examine the relationship between average daily rehabilitation time (ADRT) and risk of IADL decline during acute hospitalization in older patients with HF.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec003\">\n<jats:title>Methods<\/jats:title>\n<jats:p>Four hundred eleven older patients who were hospitalized due to acute HF and underwent rehabilitation were divided into three groups based on the tertile of the ADRT: short, intermediate, and long groups. IADL was assessed by the National Center for Geriatrics and Gerontology Activities of Daily Living (NCGG-ADL) scale. Change in NCGG-ADL (\u0394 NCGG-ADL) was calculated by subtracting the pre-hospitalization score from the at-discharge score and IADL decline was defined as \u0394 NCGG-ADL &lt; = \u22121 point. Logistic regression analysis was carried out examining the association between ADRT and occurrence of IADL decline.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec004\">\n<jats:title>Results<\/jats:title>\n<jats:p>The ADRT was 23.9, 32.0, and 38.6 minutes in short, intermediate, and long group, respectively. The proportion of patients with IADL decline during hospitalization was 21% among all subjects and short group had the highest proportion of IADL decline (33%) and long group had the lowest proportion (14%). The long group had significantly lower odds of IADL decline compared with the short group (OR:0.475, 95% CI:0.231\u20130.975, P = 0.042). Among the items of NCGG-ADL scale, significant decreases in the \u201cgo out by oneself\u201d, \u201ctravel using a bus or train\u201d, \u201cshop for necessities\u201d, \u201cvacuum\u201d, and \u201cmanage medication\u201d were observed at discharge compared to pre-hospitalization in the short group (p&lt;0.01, p&lt;0.01, p&lt;0.01, p&lt;0.05, and p&lt;0.05).<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec005\">\n<jats:title>Conclusions<\/jats:title>\n<jats:p>The present study demonstrated that short of ADRT may be associated with the risk of IADL decline during hospitalization in older patients with HF.<\/jats:p>\n<\/jats:sec>","DOI":"10.1371\/journal.pone.0254128","type":"journal-article","created":{"date-parts":[[2021,7,2]],"date-time":"2021-07-02T18:12:28Z","timestamp":1625249548000},"page":"e0254128","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":23,"title":["Relationship between average daily rehabilitation time and decline in instrumental activity of daily living among older patients with heart failure: A preliminary analysis of a multicenter cohort study, SURUGA-CARE"],"prefix":"10.1371","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1777-7660","authenticated-orcid":true,"given":"Michitaka","family":"Kato","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuji","family":"Mori","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daisuke","family":"Watanabe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshige","family":"Onoda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keita","family":"Fujiyama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masahiro","family":"Toda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuya","family":"Kito","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2021,7,2]]},"reference":[{"key":"pone.0254128.ref001","first-page":"489","article-title":"Impending epidemic: future projection of heart failure in Japan to the year 2055.","volume":"72","author":"Y Okura","year":"2008","journal-title":"Circ J"},{"key":"pone.0254128.ref002","doi-asserted-by":"crossref","first-page":"2327","DOI":"10.1253\/circj.CJ-16-0196","article-title":"The Current Status of Cardiovascular Medicine in Japan\u2014Analysis of a Large Number of Health Records From a Nationwide Claim-Based Database, JROAD-DPC.","volume":"80","author":"S Yasuda","year":"2016","journal-title":"Circ J"},{"key":"pone.0254128.ref003","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1177\/2047487319887835","article-title":"Improvement in VO2peak predicts readmissions for cardiovascular disease and mortality in patients undergoing cardiac rehabilitation.","volume":"27","author":"N Mikkelsen","year":"2020","journal-title":"Eur J Prev Cardiol"},{"key":"pone.0254128.ref004","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1016\/j.acvd.2019.07.003","article-title":"Physical activity for patients with heart failure: Position paper from the heart failure (GICC) and cardiac rehabilitation (GERS-P) Working Groups of the French Society of Cardiology.","volume":"112","author":"F Zores","year":"2019","journal-title":"Arch Cardiovasc Dis"},{"key":"pone.0254128.ref005","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1161\/CIRCHEARTFAILURE.114.001542","article-title":"Activities of daily living and outcomes in heart failure","volume":"8","author":"SM Dunlay","year":"2015","journal-title":"Circ Heart Fail"},{"key":"pone.0254128.ref006","unstructured":"Guo HJ, Sapra A. 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