{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T20:49:54Z","timestamp":1792788594543,"version":"4.5.0"},"reference-count":26,"publisher":"Public Library of Science (PLoS)","issue":"7","license":[{"start":{"date-parts":[[2021,7,23]],"date-time":"2021-07-23T00:00:00Z","timestamp":1626998400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Center for International Reproductive Health Training"},{"name":"Center for International Reproductive Health Training"},{"name":"Center for International Reproductive Health Training"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Over the past two decades non-communicable diseases (NCDs) have steadily increased as a cause of worldwide disability and mortality with a concomitant decrease in disease burden from communicable, maternal, neonatal and nutritional conditions. Congenital anomalies, the most common NCD affecting children, have recently become the fifth leading cause of under-five mortality worldwide, ahead of other conditions such as malaria, neonatal sepsis and malnutrition. Genetic counseling has been shown to be an effective method to decrease the impact of congenital anomalies and genetic conditions but is absent in almost all sub-Saharan Africa countries. To address this need for counseling services we designed and implemented the first broad-based genetic counseling curriculum in Ethiopia, launching it at St. Paul\u2019s Millennium Medical College (SPHMMC) in Addis Ababa, Ethiopia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec002\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The curriculum, created by Michigan Medicine and SPHMMC specialists, consisted of medical knowledge and genetic counseling content and was delivered to two cohorts of nurses. Curriculum evaluation consisted of satisfaction surveys and pre- and post-assessments covering medical knowledge and genetic counseling content. Following Cohort 1 training, the curriculum was modified to increase the medical knowledge material and decrease Western genetic counseling principles material.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec003\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Both cohorts reported high levels of satisfaction but felt the workshop was too short. No significant improvements in assessment scores were seen for Cohort 1 in terms of total scores and medical knowledge and genetic counseling-specific questions. Following curriculum modification, improvements were seen in Cohort 2 with an increase in total assessment scores from 63% to 73% (p = 0.043), with medical knowledge-specific questions increasing from 57% to 79% (p = 0.01) with no significant change in genetic counseling-specific scores. Multiple logistic, financial, cultural and systems-specific barriers were identified with recommendations for their consideration presented.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec004\">\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Genetics medical knowledge of Ethiopian nurses increased significantly following curriculum delivery though difficulty was encountered with Western genetic counseling material.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1371\/journal.pone.0255278","type":"journal-article","created":{"date-parts":[[2021,7,23]],"date-time":"2021-07-23T13:31:52Z","timestamp":1627047112000},"page":"e0255278","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":17,"title":["The introduction of genetic counseling in Ethiopia: Results of a training workshop and lessons learned"],"prefix":"10.1371","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8254-0216","authenticated-orcid":true,"given":"Shane C.","family":"Quinonez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bridget C.","family":"O\u2019Connor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0458-1952","authenticated-orcid":true,"given":"Michelle F.","family":"Jacobs","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atnafu","family":"Mekonnen Tekleab","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayalew","family":"Marye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Delayehu","family":"Bekele","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beverly M.","family":"Yashar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erika","family":"Hanson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abate","family":"Yeshidinber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Getahun","family":"Wedaje","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2021,7,23]]},"reference":[{"key":"pone.0255278.ref001","unstructured":"Christianson A, Howson C. 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Nature Publishing Group"},{"key":"pone.0255278.ref013","first-page":"1","article-title":"Ethical, social, and cultural issues related to clinical genetic testing and counseling in low- and middle-income countries: a systematic review","author":"A Zhong","year":"2018","journal-title":"Genetics in Medicine"},{"key":"pone.0255278.ref014","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1159\/000433518","article-title":"Translational Genomics in Low- and Middle-Income Countries: Opportunities and Challenges","volume":"18","author":"F Tekola-Ayele","year":"2015","journal-title":"Public Health Genomics"},{"key":"pone.0255278.ref015","article-title":"Prevalence of high bloodpressure, hyperglycemia, dyslipidemia, metabolic syndrome and their determinants in Ethiopia: Evidences from the National NCDs STEPS Survey, 2015","author":"YF Gebreyes","year":"2018","journal-title":"PLoS ONE. Public Library of Science"},{"key":"pone.0255278.ref016","article-title":"Patient preferences for prenatal testing and termination of pregnancy for congenital anomalies and genetic diseases in Ethiopia","author":"D Brooks","year":"2019","journal-title":"Prenatal Diagnosis"},{"key":"pone.0255278.ref017","article-title":"Introducing medical genetics services in Ethiopia using the MiGene Family History App","author":"SC Quinonez","year":"2019","journal-title":"Genetics in Medicine"},{"key":"pone.0255278.ref018","article-title":"Knowledge and Attitudes about Genetic Counseling in Patients at a Major Hospital in Addis Ababa, Ethiopia","author":"MF Jacobs","year":"2020","journal-title":"Journal of Genetic Counseling"},{"key":"pone.0255278.ref019","article-title":"Recommendations of core competencies in genetics essential for all health professionals","author":"J Jenkins","year":"2001","journal-title":"Genetics in Medicine"},{"key":"pone.0255278.ref020","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1002\/ajmg.c.31607","article-title":"Genetic counseling globally: Where are we now?","volume":"178","author":"KE Ormond","year":"2018","journal-title":"American Journal of Medical Genetics Part C: Seminars in Medical Genetics"},{"key":"pone.0255278.ref021","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1111\/j.1365-2923.2004.01747.x","article-title":"Acquisition of communication skills in postgraduate training for general practice","volume":"38","author":"AWM Kramer","year":"2004","journal-title":"Medical Education"},{"key":"pone.0255278.ref022","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1080\/01421590802402247","article-title":"Setting and maintaining standards in multiple choice examinations: AMEE Guide No. 37","volume":"30","author":"RC Bandaranayake","year":"2008","journal-title":"Medical Teacher"},{"key":"pone.0255278.ref023","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12939-016-0488-4","article-title":"\u201cThe way the country has been carved up by researchers\u201d: ethics and power in north-south public health research","volume":"15","author":"A Walsh","year":"2016","journal-title":"International Journal for Equity in Health"},{"key":"pone.0255278.ref024","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0230309","article-title":"Communicative challenges among physicians, patients, and family caregivers in cancer care: An exploratory qualitative study in Ethiopia","volume":"15","author":"BG Kebede","year":"2020","journal-title":"PLoS ONE"},{"key":"pone.0255278.ref025","article-title":"Knowledge and attitudes about genetic counseling in patients at a major hospital in Addis Ababa","author":"MF Jacobs","year":"2020","journal-title":"Ethiopia. Journal of Genetic Counseling"},{"key":"pone.0255278.ref026","doi-asserted-by":"crossref","first-page":"213","DOI":"10.2147\/IJWH.S131139","article-title":"Health care decision making autonomy of women from rural districts of Southern Ethiopia: A community based cross-sectional study","volume":"9","author":"M Alemayehu","year":"2017","journal-title":"International Journal of Women\u2019s Health"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0255278","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,1,5]],"date-time":"2023-01-05T04:47:16Z","timestamp":1672894036000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0255278"}},"subtitle":[],"editor":[{"given":"Vijayaprakash","family":"Suppiah","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2021,7,23]]},"references-count":26,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2021,7,23]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0255278","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,7,23]]}}}