{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T11:07:56Z","timestamp":1767956876845,"version":"3.49.0"},"reference-count":35,"publisher":"Public Library of Science (PLoS)","issue":"8","license":[{"start":{"date-parts":[[2021,8,20]],"date-time":"2021-08-20T00:00:00Z","timestamp":1629417600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\">\n<jats:title>Introduction<\/jats:title>\n<jats:p>Corneal transplantation is the only treatment option for corneal blindness to restore sight. However, there is a disproportionate imbalance between the demand and supply of corneal tissue in Ethiopia. This is because accessing corneal tissue is reliant on people who are willing to donate corneas after death.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec002\">\n<jats:title>Objective<\/jats:title>\n<jats:p>This study aimed to assess the proportion of willingness to donate cornea and associated factors among adult patients attending at University of Gondar comprehensive and specialized hospital.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec003\">\n<jats:title>Method<\/jats:title>\n<jats:p>Institutional based cross-sectional study was conducted from July 13 to July 28, 2020, through a face-to-face interview. A total of 451 samples were selected using systematic random sampling. The data were entered into Epidemiological information version 7 and exported to statistical package for social science version 20 for formal analysis. Variables with a P-value of &lt; 0.20 in a bi-variable logistic regression were entered into the multivariable logistic regression and those variables with a p-value of &lt; 0.05 were taken as statistically significant. The strength of association was shown using the odds ratio with a 95% confidence interval.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec004\">\n<jats:title>Result<\/jats:title>\n<jats:p>A total of 408 adults participated in this study with a response rate of 90% and the proportion of willingness to donate cornea was 179(43.90%). Participants who had a religious belief in Christianity (AOR = 3.23 (95% CI: 1.09\u20139.57)) and good knowledge about corneal donation (AOR = 5.45(95%CI: 2.69\u201311.18)) were positively associated with the willingness of corneal donation. On the other side, the age group above 43 years (AOR = 0.31(95% CI: 0.11\u20130.89) was negatively associated with the willingness of corneal donation.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec005\">\n<jats:title>Conclusion<\/jats:title>\n<jats:p>The proportion of willingness to donate cornea 43.9% among participants attending Gondar University Comprehensive and Specialized Hospital. Age group greater than 43 years, religion of Christianity and good knowledge were associated with the willingness of corneal donation.<\/jats:p>\n<\/jats:sec>","DOI":"10.1371\/journal.pone.0256102","type":"journal-article","created":{"date-parts":[[2021,8,20]],"date-time":"2021-08-20T18:23:26Z","timestamp":1629483806000},"page":"e0256102","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":5,"title":["Willingness of corneal donation and its associated factors among adult patients attending Gondar University Comprehensive and Specialized Hospital"],"prefix":"10.1371","volume":"16","author":[{"given":"Eyerus","family":"Gesesse","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0707-4497","authenticated-orcid":true,"given":"Sofonias Addis","family":"Fekadu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gizachew Tilahun","family":"Belete","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2021,8,20]]},"reference":[{"issue":"11","key":"pone.0256102.ref001","doi-asserted-by":"crossref","first-page":"e003471","DOI":"10.1136\/bmjopen-2013-003471","article-title":"The economic burden of visual impairment and blindness: a systematic review","volume":"3","author":"J K\u00f6berlein","year":"2013","journal-title":"BMJ Open"},{"key":"pone.0256102.ref002","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1001\/archopht.125.4.544","article-title":"Economic impact of visual impairment and blindness in the United States","volume":"125","author":"KD Frick","journal-title":"Arch Ophthalmol"},{"key":"pone.0256102.ref003","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1007\/s11136-008-9336-3","article-title":"Health-related quality of life following blind rehabilitation","volume":"17","author":"T Kuyk","year":"2008","journal-title":"Qual Life Res"},{"key":"pone.0256102.ref004","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1167\/iovs.14-15848","article-title":"Major depressive and anxiety disorders in visually impaired older adults","volume":"56","author":"HP Van der Aa","year":"2015","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"12","key":"pone.0256102.ref005","doi-asserted-by":"crossref","DOI":"10.1016\/S2214-109X(17)30393-5","article-title":"Global causes of blindness and distance vision impairment 1990\u20132020: a systematic review and meta-analysis","volume":"5","author":"SR Flaxman","year":"2017","journal-title":"The Lancet Global Health"},{"key":"pone.0256102.ref006","first-page":"214","article-title":"Corneal blindness: a global perspective","volume":"79","author":"JP Whitcher","year":"2001","journal-title":"Bulletin of the world health organization"},{"key":"pone.0256102.ref007","volume-title":"Global Data on Visual Impairments","author":"World Organization","year":"2012"},{"issue":"3","key":"pone.0256102.ref008","first-page":"204","article-title":"Prevalence and causes of blindness and low vision in Ethiopia","volume":"21","author":"Y Berhane","year":"2007","journal-title":"Ethiopian Journal of Health Development"},{"issue":"5","key":"pone.0256102.ref009","doi-asserted-by":"crossref","first-page":"423","DOI":"10.4103\/0301-4738.100540","article-title":"Turning the tide of corneal blindness","volume":"60","author":"MS Oliva","year":"2012","journal-title":"Indian journal of ophthalmology"},{"key":"pone.0256102.ref010","unstructured":"World Organization. Action plan for the prevention of avoidable blindness and visual impairment, 2009\u20132013. 2010."},{"issue":"2","key":"pone.0256102.ref011","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1111\/xen.12082","article-title":"Corneal blindness and xenotransplantation","volume":"21","author":"V Lamm","year":"2014","journal-title":"Xenotransplantation"},{"issue":"2","key":"pone.0256102.ref012","doi-asserted-by":"crossref","first-page":"662","DOI":"10.5455\/2320-6012.ijrms20140554","article-title":"A study to assess awareness on eye donation and willingness to pledge eyes for donation in adult population in Gwalior district (MP), India","volume":"2","author":"R Tiwari","year":"2014","journal-title":"Int J Res Med Sci"},{"issue":"3","key":"pone.0256102.ref013","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1016\/j.ajo.2013.04.034","article-title":"Indications and outcomes of corneal transplantation in geriatric patients","volume":"156","author":"F Duman","year":"2013","journal-title":"American journal of ophthalmology"},{"issue":"2","key":"pone.0256102.ref014","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1136\/bjophthalmol-2014-305945","article-title":"Prevalence of corneal diseases in the rural Indian population: the Corneal Opacity Rural Epidemiological (CORE) study","volume":"99","author":"N Gupta","year":"2015","journal-title":"British Journal of Ophthalmology"},{"issue":"71","key":"pone.0256102.ref015","first-page":"46","article-title":"Eye banking: an introduction","volume":"22","author":"GN Rao","year":"2009","journal-title":"Community eye health"},{"issue":"2","key":"pone.0256102.ref016","article-title":"Status of eye donation awareness and its associated factors among adults in rural Pondicherry","volume":"9","author":"R Patil","year":"2015","journal-title":"Journal of clinical and diagnostic research: 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Gessesse","year":"2013","journal-title":"JOECSA"},{"issue":"1","key":"pone.0256102.ref020","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1186\/s12886-017-0577-1","article-title":"Willingness to donate eyes and its associated factors among adults in Gondar town, North West Ethiopia","volume":"17","author":"MS Hussen","year":"2017","journal-title":"BMC ophthalmology"},{"issue":"7","key":"pone.0256102.ref021","doi-asserted-by":"crossref","first-page":"1","DOI":"10.9790\/0853-1607010106","article-title":"Knowledge, attitude and willingness for eye donation in general population of Odisha in eastern India","volume":"16","author":"S Panigrahi","year":"2017","journal-title":"IOSR J Dent Med Sci"},{"issue":"4","key":"pone.0256102.ref022","first-page":"258","article-title":"Eye donation: awareness and willingness among patients attending a tertiary eye center in Ghana","volume":"33","author":"E Ackuaku-Dogbe","year":"2013","journal-title":"West Afr J 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BMC ophthalmology"},{"issue":"1","key":"pone.0256102.ref030","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/S1001-9294(13)60014-0","article-title":"Awareness of cornea donation of registered tissue donors in Nanjing","volume":"28","author":"T Chu","year":"2013","journal-title":"Chinese Medical Sciences Journal"},{"issue":"1","key":"pone.0256102.ref031","doi-asserted-by":"crossref","first-page":"43","DOI":"10.4103\/0976-6677.193867","article-title":"Concerns regarding eye donation among health seekers attending a reputed eye care institution in North Kerala","volume":"28","author":"P Prabhu","year":"2016","journal-title":"Kerala Journal of Ophthalmology"},{"issue":"3","key":"pone.0256102.ref032","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1111\/j.1600-6143.2009.02986.x","article-title":"Specific unwillingness to donate eyes: the impact of disfigurement, knowledge and procurement on corneal donation","volume":"10","author":"M Lawlor","year":"2010","journal-title":"American Journal of Transplantation"},{"issue":"1","key":"pone.0256102.ref033","doi-asserted-by":"crossref","first-page":"41","DOI":"10.4103\/0301-4738.73727","article-title":"Eye donation\u2013Awareness and willingness among attendants of patients at various clinics in Melaka, Malaysia","volume":"59","author":"S Bhandary","year":"2011","journal-title":"Indian journal of ophthalmology"},{"key":"pone.0256102.ref034","unstructured":"Alibrahim E, Al Jindan M. Knowledge and attitude about corneal donation and transplantation in Eastern province: a population-based study."},{"issue":"10","key":"pone.0256102.ref035","doi-asserted-by":"crossref","first-page":"1362","DOI":"10.1097\/ICO.0000000000000943","article-title":"Attitudes and Knowledge Concerning Corneal Donation in a Population-Based Sample of Urban Chinese Adults","volume":"35","author":"X Wang","year":"2016","journal-title":"Cornea"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0256102","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,20]],"date-time":"2021-08-20T18:24:08Z","timestamp":1629483848000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0256102"}},"subtitle":[],"editor":[{"given":"Asaf","family":"Achiron","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2021,8,20]]},"references-count":35,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2021,8,20]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0256102","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,8,20]]}}}