{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T22:31:38Z","timestamp":1782253898247,"version":"3.54.5"},"reference-count":57,"publisher":"Public Library of Science (PLoS)","issue":"8","license":[{"start":{"date-parts":[[2021,8,19]],"date-time":"2021-08-19T00:00:00Z","timestamp":1629331200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:p>Inclusion body hepatitis (IBH) is, in some cases, a fatal disease affecting fowl by adenovirus strains which are subdivided into 5 species (A-E). In the current study, we investigated sequences from the Loop L1 region of the hexon gene of sequences of adenovirus field stains 1\/A and 11\/D isolated from a poultry flock co-infected with IBH and avian reoviruses ARVs. In early 2021, an epidemiologic survey highlighted the coinfection adenoviruses with other viruses (orthoreovirus infection) as being particularly deleterious within the poultry industry. Here, we investigated the Loop L1 HVR1-4 region of the hexon gene with relative synonymous codon usage (RSCU) designation and RSCU inclusive of all the mutations. These are the first results that have been presented on fowl adenovirus species A and D with simultaneous reovirus infection in 38-days old broiler chickens in Poland.<\/jats:p>","DOI":"10.1371\/journal.pone.0256137","type":"journal-article","created":{"date-parts":[[2021,8,19]],"date-time":"2021-08-19T18:40:54Z","timestamp":1629398454000},"page":"e0256137","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":11,"title":["Fowl adenovirus strains 1\/A and 11\/D isolated from birds with reovirus infection"],"prefix":"10.1371","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3714-0552","authenticated-orcid":true,"given":"Jowita Samanta","family":"Niczyporuk","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wojciech","family":"Kozdrun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanna","family":"Czekaj","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalia","family":"Stys-Fijol","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2021,8,19]]},"reference":[{"key":"pone.0256137.ref001","first-page":"251","volume-title":"Diseases of poultry","author":"SD Fitzgerald","year":"2008","edition":"12"},{"key":"pone.0256137.ref002","doi-asserted-by":"crossref","first-page":"421","DOI":"10.2478\/jvetres-2018-0079","article-title":"Occurrence of reovirus (ARV) infections in poultry flocks in Poland in 2010\u20132017.","volume":"62","author":"H Czekaj","year":"2018","journal-title":"J Vet Res"},{"key":"pone.0256137.ref003","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1007\/BF00569038","article-title":"LF Lee.Marek\u2019s disease virus gene clones encoding virus-specific phosphorylated polypeptides and serological characterization of fusion proteins","volume":"3","author":"ZZ Cui","year":"1990","journal-title":"Virus Genes"},{"key":"pone.0256137.ref004","doi-asserted-by":"crossref","first-page":"435","DOI":"10.2478\/v10213-012-0077-2","article-title":"Occurrence of Adenovirus Field Strains in Birds Infected with Marek\u2019S Disease Virus","volume":"56","author":"JS Niczyporuk","year":"2012","journal-title":"Bull Vet Inst Pulawy"},{"key":"pone.0256137.ref005","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1637\/8478-100808-Reg.1","article-title":"Molecular characterization ofchicken infectious anemia virus circulating in Argentina during 2007","volume":"53","author":"MI Craig","year":"2009","journal-title":"Avian Dis"},{"key":"pone.0256137.ref006","doi-asserted-by":"crossref","first-page":"2426","DOI":"10.3382\/ps.2010-00911","article-title":"Molecular characterization of chicken infectious anemia virusesdetected from breeder and broiler chickens in South Korea","volume":"89","author":"HR Kim","year":"2010","journal-title":"Poult. 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