{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T07:20:49Z","timestamp":1772781649511,"version":"3.50.1"},"reference-count":67,"publisher":"Public Library of Science (PLoS)","issue":"9","license":[{"start":{"date-parts":[[2021,9,29]],"date-time":"2021-09-29T00:00:00Z","timestamp":1632873600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:p>This study aimed to assess potential feeding effect of camel milk curd mass and its mixes to experimental rat\u2019s blood serum biochemical parameters, enzymatic activity and the peptide toxicity. Fifty healthy male Sprague-Dawley rats were divided into five groups (n = 10 each). Each group was fed with camel milk pure curd mass and its mixes for 16 days. At the end of the experiment, rats were sacrificed to collect the samples from the blood serum. Blood serum biochemical parameters total protein, cholesterol, glucose, albumin, triglycerides; the enzymatic activities of alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase were determined on the A25 automatic analyser, and peptide toxicity analysed by the reference method. The statistical data have shown no significant differences in body weight gain in all groups. Total protein decreased in group II, IV, and V; however, it increased in group III compared to the control group. Cholesterol grew up in group II and it slightly increased in group V, dropped in groups III and IV compared to group I result. Glucose increased in groups II, III, IV compared to group I; still, group V results show a slight decrease. Albumin decreased in group IV, yet in group V it increased than the group I result. Simultaneously, groups II and III results were changed with less percentage. Triglyceride grew up in groups II, V, and it dropped significantly in groups III, IV compared to the control group. De Ritis ratio of enzymes in groups II, III, and IV fluctuated between 1.31 and 0.98 IU\/L; however, group V demonstrated significant data versus group I. Diets peptide toxicity in all groups was lower than control group data. The experimental results indicated that curd mass from camel milk could be used as a pure or with additives and it did not discover the observed side effects.<\/jats:p>","DOI":"10.1371\/journal.pone.0256661","type":"journal-article","created":{"date-parts":[[2021,9,29]],"date-time":"2021-09-29T18:20:28Z","timestamp":1632939628000},"page":"e0256661","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":11,"title":["The effect of camel milk curd masses on rats blood serum biochemical parameters: Preliminary study"],"prefix":"10.1371","volume":"16","author":[{"given":"Fatima","family":"Dikhanbayeva","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0383-4946","authenticated-orcid":true,"given":"Elmira","family":"Zhaxybayeva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhuldyz","family":"Smailova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arman","family":"Issimov","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6945-4025","authenticated-orcid":true,"given":"Zhechko","family":"Dimitrov","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Unzira","family":"Kapysheva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nidhi","family":"Bansal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2021,9,29]]},"reference":[{"issue":"4","key":"pone.0256661.ref001","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1016\/j.clnu.2011.01.009","article-title":"Body composition changes over 9 years in healthy elderly subjects and impact of physical activity","volume":"30","author":"L Genton","year":"2011","journal-title":"Clin Nutr"},{"issue":"7","key":"pone.0256661.ref002","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1016\/S0047-6374(01)00426-2","article-title":"Ageing of the brain","volume":"123","author":"BH Anderton","year":"2002","journal-title":"Mech Ageing Dev"},{"issue":"8","key":"pone.0256661.ref003","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1161\/CIRCRESAHA.111.246876","article-title":"The intersection between aging and cardiovascular disease","volume":"110","author":"BJ North","year":"2012","journal-title":"Circ Res"},{"issue":"24","key":"pone.0256661.ref004","doi-asserted-by":"crossref","first-page":"2604","DOI":"10.1200\/JCO.2014.55.1432","article-title":"Biology of cancer and aging: a complex association with cellular senescence","volume":"32","author":"C Falandry","year":"2014","journal-title":"J Clin Oncol"},{"issue":"12","key":"pone.0256661.ref005","doi-asserted-by":"crossref","first-page":"2650","DOI":"10.2337\/dc12-1801","article-title":"Diabetes in older adults","volume":"35","author":"MS Kirkman","year":"2012","journal-title":"Diabetes Care"},{"key":"pone.0256661.ref006","first-page":"43","article-title":"Aging and dyslipidemia: a review of potential mechanisms. 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