{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T03:01:30Z","timestamp":1787022090730,"version":"build-2736575974"},"reference-count":41,"publisher":"Public Library of Science (PLoS)","issue":"10","license":[{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\">\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>\n                      <jats:italic>Taenia solium<\/jats:italic>\n                      (Ts) cysticercosis is a neglected zoonotic disease particularly prevalent in Madagascar. Few data are available for children, current data mainly rely on antibody prevalence. We sought to determine the Ts-antigen seroprevalence\u2013determining active cysticercosis\u2014amongst school children from various cities in Madagascar (excluding the capital) and evaluated associated risk factors.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec002\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In seven cities in Madagascar, the presence of cysticercosis in school children (n = 1751) was investigated in 2007 using the B158\/B60 antigen (Ag)-ELISA.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec003\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The overall prevalence based on Ag detection was 27.7% [95%CI: 10\u201337%]. Risk factors associated with Ag positivity were age, biotope, altitude and annual average rainfall.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec004\">\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>These results highlight the high prevalence of active cysticercosis in Madagascar among school children in an urban setting. This high prevalence as well as the risk factors unraveled point to the emergency to implement appropriate Public Health measure son a national scale.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1371\/journal.pone.0258035","type":"journal-article","created":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T15:08:14Z","timestamp":1633100894000},"page":"e0258035","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":3,"title":["Hyperendemicity of cysticercosis in Madagascar: Novel insights from school children population-based antigen prevalence study"],"prefix":"10.1371","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7472-7160","authenticated-orcid":true,"given":"Jean-Fran\u00e7ois","family":"Carod","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fr\u00e9d\u00e9ric","family":"Mauny","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne Laure","family":"Parmentier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3801-5297","authenticated-orcid":true,"given":"Maxime","family":"Desmarets","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahenintsoa","family":"Rakotondrazaka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alice","family":"Brembilla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V\u00e9ronique","family":"Dermauw","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6540-2746","authenticated-orcid":true,"given":"Julien","family":"Razafimahefa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rondro Mamitiana","family":"Ramahefarisoa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcellin","family":"Andriantseheno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Bailly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1357-4495","authenticated-orcid":true,"given":"Didier","family":"M\u00e9nard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5381-7987","authenticated-orcid":true,"given":"Pierre","family":"Dorny","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2021,10,1]]},"reference":[{"issue":"10","key":"pone.0258035.ref001","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1111\/j.1528-1157.1998.tb01287.x","article-title":"Cysticercosis and epilepsy: a critical review","volume":"39","author":"A Carpio","year":"1998","journal-title":"Epilepsia"},{"issue":"11","key":"pone.0258035.ref002","doi-asserted-by":"crossref","first-page":"e870","DOI":"10.1371\/journal.pntd.0000870","article-title":"A Systematic Review of the Frequency of Neurocyticercosis with a Focus on People with Epilepsy","volume":"4","author":"PC Ndimubanzi","year":"2010","journal-title":"PLoS Negl Trop Dis"},{"key":"pone.0258035.ref003","doi-asserted-by":"crossref","first-page":"159821","DOI":"10.1100\/2012\/159821","article-title":"Neurocysticercosis: a review","volume":"2012","author":"OH Del Brutto","year":"2012","journal-title":"ScientificWorldJournal"},{"issue":"6","key":"pone.0258035.ref004","first-page":"423","article-title":"Current situation of the most frequent zoonosis in the world","volume":"146","author":"R. 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