{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T01:30:08Z","timestamp":1792114208597,"version":"4.4.0"},"reference-count":61,"publisher":"Public Library of Science (PLoS)","issue":"10","license":[{"start":{"date-parts":[[2021,10,11]],"date-time":"2021-10-11T00:00:00Z","timestamp":1633910400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Agencia Nacional de Investigaci\u00f3n y Desarrollo (ANID) - Fondecyt Regular","award":["1181724"],"award-info":[{"award-number":["1181724"]}]},{"name":"Agencia Nacional de Investigaci\u00f3n y Desarrollo (ANID) \u2013 Millennium Science Initiative Program","award":["NCS17_035"],"award-info":[{"award-number":["NCS17_035"]}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\">\n<jats:title>Background<\/jats:title>\n<jats:p>Substance use is highly prevalent among Chilean adolescents, and the damage it causes at the neurobiological, psychological, and social levels is known. However, there are no validated screening instruments that also assess risk and protective factors for this population in Chile, which is essential for evaluating future prevention interventions.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec002\">\n<jats:title>Objective<\/jats:title>\n<jats:p>To determine the psychometric properties of the European Drug Addiction Prevention Trial Questionnaire (EU-Dap) questionnaire.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec003\">\n<jats:title>Methods<\/jats:title>\n<jats:p>A cross-sectional study was carried out in 13 schools in the city of Santiago de Chile. The sample included 2261 adolescents ranging from 10 to 14 years old. Linguistic and cultural adaptation was assessed using focus groups with adolescents, the construct validity was evaluated using confirmatory factor analysis, and measures of its reliability were also determined. Furthermore, the associations regarding risk and protective factors with substance use were explored.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec004\">\n<jats:title>Results<\/jats:title>\n<jats:p>Substance use questions were well understood and seemed to adequately capture the consumption of different drugs. Regarding the subscales of risk and protective factors, the analyses showed that most subscales had good psychometric properties, and few needed some degree of improvement (e.g., some items were removed). After the changes, most final subscales had good or adequate goodness of fit adjustments and good or acceptable internal consistency. Finally, the main associated factors with the substance use outcomes were: future substance use and school bonding for tobacco use; negative beliefs about alcohol, future substance use, school bonding and refusal skills for alcohol use; and negative beliefs about marihuana, positive attitudes towards drugs, risk perception, and substance abuse index for marihuana use. Normative beliefs increased the risk for all substances use.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec005\">\n<jats:title>Conclusions<\/jats:title>\n<jats:p>The current findings suggest that the EU-Dap is a valid and reliable instrument, and it may help to evaluate the effectiveness of drug use prevention interventions.<\/jats:p>\n<\/jats:sec>","DOI":"10.1371\/journal.pone.0258288","type":"journal-article","created":{"date-parts":[[2021,10,11]],"date-time":"2021-10-11T19:52:39Z","timestamp":1633981959000},"page":"e0258288","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":15,"title":["Validation of the European Drug Addiction Prevention Trial Questionnaire (EU-Dap) for substance use screening and to assess risk and protective factors among early adolescents in Chile"],"prefix":"10.1371","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8367-2229","authenticated-orcid":true,"given":"Saray","family":"Ram\u00edrez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5249-0505","authenticated-orcid":true,"given":"Sof\u00eda","family":"Gana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda In\u00e9s","family":"Godoy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Valenzuela","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ricardo","family":"Araya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6650-6018","authenticated-orcid":true,"given":"Jorge","family":"Gaete","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2021,10,11]]},"reference":[{"issue":"3","key":"pone.0258288.ref001","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/S2215-0366(15)00508-8","article-title":"The increasing global health priority of substance use in young people","volume":"3","author":"L Degenhardt","year":"2016","journal-title":"Lancet Psychiatry"},{"issue":"2","key":"pone.0258288.ref002","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1080\/10826084.2018.1517797","article-title":"Early Adolescent Patterns of Alcohol and Tobacco Use in Eight Association of South-East Asian Nations (ASEAN) Member States.","volume":"54","author":"SA Hong","year":"2019","journal-title":"Subst Use Misuse."},{"issue":"30","key":"pone.0258288.ref003","doi-asserted-by":"crossref","first-page":"10937","DOI":"10.1523\/JNEUROSCI.5302-10.2011","article-title":"Longitudinal development of human brain wiring continues from childhood into adulthood","volume":"31","author":"C Lebel","year":"2011","journal-title":"J Neurosci"},{"issue":"Pt A","key":"pone.0258288.ref004","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.bbr.2017.02.025","article-title":"Cannabis and alcohol use, and the developing brain","volume":"325","author":"AD Meruelo","year":"2017","journal-title":"Behav Brain Res"},{"issue":"5","key":"pone.0258288.ref005","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1007\/s11920-016-0689-y","article-title":"Alcohol and Drug Use and the Developing Brain.","volume":"18","author":"LM Squeglia","year":"2016","journal-title":"Curr Psychiatry Rep"},{"issue":"2","key":"pone.0258288.ref006","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1037\/a0029111","article-title":"Adolescent brain development, substance use, and psychotherapeutic change.","volume":"27","author":"R Wetherill","year":"2013","journal-title":"Psychol Addict Behav."},{"key":"pone.0258288.ref007","volume":"2019","author":"M Hynes","year":"2019","journal-title":"Informe sobre el consumo de drogas en las Am\u00e9ricas"},{"key":"pone.0258288.ref008","volume":"2017","author":"E Pizarro","year":"2019","journal-title":"D\u00e9cimo Segundo Estudio Nacional de drogas en poblaci\u00f3n escolar de Chile"},{"key":"pone.0258288.ref009","doi-asserted-by":"crossref","first-page":"3241","DOI":"10.2147\/NDT.S187419","article-title":"The association between depression, anxiety and substance use among Canadian post-secondary students.","volume":"14","author":"S Esmaeelzadeh","year":"2018","journal-title":"Neuropsychiatr Dis Treat"},{"issue":"3","key":"pone.0258288.ref010","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S2215-0366(16)00013-4","article-title":"Why young people\u2019s substance use matters for global health","volume":"3","author":"WD Hall","year":"2016","journal-title":"Lancet Psychiatry"},{"issue":"7578","key":"pone.0258288.ref011","doi-asserted-by":"crossref","first-page":"S161","DOI":"10.1038\/nature16030","article-title":"A focus on adolescence to reduce neurological, mental health and substance-use disability","volume":"527","author":"LL Davidson","year":"2015","journal-title":"Nature"},{"key":"pone.0258288.ref012","unstructured":"Superintendencia de Salud. Casos GES (AUGE) acumulados a diciembre de 2019 2020 [cited 2020 17 Jun]. Available from: http:\/\/www.supersalud.gob.cl\/documentacion\/666\/w3-article-19244.html."},{"key":"pone.0258288.ref013","unstructured":"Fondo Nacional de Salud. Aranceles Modalidad Atenci\u00f3n Institucional 2020 [cited 2020 17 Jun]. Available from: https:\/\/www.fonasa.cl\/sites\/fonasa\/prestadores\/modalidad-atencion-institucional."},{"key":"pone.0258288.ref014","unstructured":"Egresos Hospitalarios [Internet]. 2017 [cited 19 Dic]. Available from: http:\/\/www.deis.cl\/estadisticas-egresoshospitalarios\/."},{"issue":"1","key":"pone.0258288.ref015","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1007\/s11121-016-0723-7","article-title":"A Meta-analysis of the Effectiveness of Interactive Middle School Cannabis Prevention Programs.","volume":"18","author":"SE Lize","year":"2017","journal-title":"Prev Sci."},{"issue":"Suppl 1 M6","key":"pone.0258288.ref016","doi-asserted-by":"crossref","first-page":"102","DOI":"10.2174\/1745017901511010102","article-title":"A Systematic Review of School-Based Alcohol and other Drug Prevention Programs.","volume":"11","author":"R Agabio","year":"2015","journal-title":"Clin Pract Epidemiol Ment Health"},{"issue":"5","key":"pone.0258288.ref017","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1016\/j.ypmed.2008.06.018","article-title":"The effectiveness of a school-based substance abuse prevention program: EU-Dap cluster randomised controlled trial.","volume":"47","author":"F Faggiano","year":"2008","journal-title":"Prev Med"},{"issue":"1\u20132","key":"pone.0258288.ref018","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.drugalcdep.2009.11.018","article-title":"The effectiveness of a school-based substance abuse prevention program: 18-month follow-up of the EU-Dap cluster randomized controlled trial","volume":"108","author":"F Faggiano","year":"2010","journal-title":"Drug Alcohol Depend"},{"issue":"141","key":"pone.0258288.ref019","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1002\/yd.20087","article-title":"\u201cUnplugged,\u201d a European school-based program for substance use prevention among adolescents: overview of results from the EU-Dap trial.","volume":"2014","author":"FD Vigna-Taglianti","year":"2014","journal-title":"New Dir Youth Dev"},{"issue":"12","key":"pone.0258288.ref020","first-page":"Cd003020","article-title":"Universal school-based prevention for illicit drug use.","volume":"2014","author":"F Faggiano","year":"2014","journal-title":"Cochrane Database Syst Rev."},{"issue":"6","key":"pone.0258288.ref021","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1001\/archpedi.153.6.591","article-title":"A new brief screen for adolescent substance abuse.","volume":"153","author":"JR Knight","year":"1999","journal-title":"Arch Pediatr Adolesc Med"},{"issue":"6","key":"pone.0258288.ref022","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1111\/j.1360-0443.1993.tb02093.x","article-title":"Development of the Alcohol Use Disorders Identification Test (AUDIT): WHO Collaborative Project on Early Detection of Persons with Harmful Alcohol Consumption\u2014II.","volume":"88","author":"JB Saunders","year":"1993","journal-title":"Addiction"},{"issue":"4","key":"pone.0258288.ref023","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1111\/j.1360-0443.2009.02859.x","article-title":"The Cannabis Use Problems Identification Test (CUPIT): development, reliability, concurrent and predictive validity among adolescents and adults.","volume":"105","author":"J Bashford","year":"2010","journal-title":"Addiction"},{"issue":"3","key":"pone.0258288.ref024","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.drugalcdep.2009.01.017","article-title":"The Alcohol Use Disorders Identification Test (AUDIT) as a screening instrument for adolescents.","volume":"103","author":"R Santis","year":"2009","journal-title":"Drug Alcohol Depend."},{"issue":"5","key":"pone.0258288.ref025","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1016\/j.jadohealth.2013.10.009","article-title":"Short-term mediating factors of a school-based intervention to prevent youth substance use in Europe.","volume":"54","author":"F Giannotta","year":"2014","journal-title":"J Adolesc Health"},{"issue":"2","key":"pone.0258288.ref026","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.ypmed.2006.09.010","article-title":"A cluster randomized controlled trial of school-based prevention of tobacco, alcohol and drug use: the EU-Dap design and study population","volume":"44","author":"F Faggiano","year":"2007","journal-title":"Prev Med"},{"issue":"4","key":"pone.0258288.ref027","doi-asserted-by":"crossref","first-page":"449","DOI":"10.3109\/10826084.2015.1117108","article-title":"Transcultural Adaptation of Questionnaire to Evaluate Drug Use Among Students: The Use of the EU-Dap European Questionnaire in Brazil.","volume":"51","author":"MC Prado","year":"2016","journal-title":"Subst Use Misuse."},{"issue":"7","key":"pone.0258288.ref028","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1007\/s11121-017-0770-8","article-title":"The #Tamojunto Drug Prevention Program in Brazilian Schools: a Randomized Controlled Trial.","volume":"18","author":"ZM Sanchez","year":"2017","journal-title":"Prev Sci."},{"issue":"1","key":"pone.0258288.ref029","first-page":"63","article-title":"[How is an instrument for measuring health to be validated?].","volume":"34","author":"A Carvajal","year":"2011","journal-title":"An Sist Sanit Navar"},{"issue":"4","key":"pone.0258288.ref030","doi-asserted-by":"crossref","first-page":"195","DOI":"10.4103\/1117-1936.173959","article-title":"Principles and methods of validity and reliability testing of questionnaires used in social and health science researches","volume":"22","author":"OA Bolarinwa","year":"2015","journal-title":"Niger Postgrad Med J"},{"key":"pone.0258288.ref031","volume-title":"Bases de la investigaci\u00f3n cualitativa: t\u00e9cnicas y procedimientos para desarrollar la teor\u00eda fundamentada:","author":"A Strauss","year":"2016"},{"key":"pone.0258288.ref032","volume-title":"Confirmatory factor analysis","author":"D. Harrington","year":"2009"},{"key":"pone.0258288.ref033","volume-title":"Surveys in social research:","author":"D De Vaus","year":"2013"},{"key":"pone.0258288.ref034","first-page":"2","article-title":"Growing up unequal: gender and socioeconomic differences in young people\u2019s health and well-being.","volume":"2014","author":"J Inchley","year":"2013","journal-title":"Health Behaviour in School-aged Children (HBSC) study: international report from the."},{"key":"pone.0258288.ref035","unstructured":"Ministerio de Educaci\u00f3n. Estad\u00edsticas de la Educaci\u00f3n 2019 [cited 2021 6 Jun]. Available from: https:\/\/centroestudios.mineduc.cl\/wp-content\/uploads\/sites\/100\/2019\/11\/ANUARIO-2018-PDF-WEB-FINALr.pdf."},{"issue":"2","key":"pone.0258288.ref036","doi-asserted-by":"crossref","first-page":"379","DOI":"10.4067\/S0718-07052016000200022","article-title":"Composici\u00f3n de g\u00e9nero en establecimientos escolares chilenos:\u00bf Afecta el rendimiento acad\u00e9mico y el ambiente escolar?","volume":"42","author":"C Villalobos Dintrans","year":"2016","journal-title":"Estudios pedag\u00f3gicos (Valdivia)."},{"key":"pone.0258288.ref037","unstructured":"Agencia de Calidad de la Educaci\u00f3n. Metodolog\u00eda de construcci\u00f3n de grupos socioecon\u00f3micos pruebas SIMCE 2013 2013 [cited 2020 18 Jun]. Available from: http:\/\/archivos.agenciaeducacion.cl\/Metodologia_de_Construccion_de_Grupos_Socioeconomicos_Simce_2013.pdf."},{"issue":"3","key":"pone.0258288.ref038","first-page":"1151","article-title":"Exploratory item factor analysis: A practical guide revised and updated.","volume":"30","author":"S Lloret-Segura","year":"2014","journal-title":"Anales de Psicolog\u00eda."},{"issue":"1","key":"pone.0258288.ref039","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1207\/s15327906mbr1201_3","article-title":"A Study Of A Measure Of Sampling Adequacy For Factor-Analytic Correlation Matrices.","volume":"12","author":"BA Cerny","year":"1977","journal-title":"Multivariate Behav Res."},{"issue":"1","key":"pone.0258288.ref040","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1007\/s11135-008-9190-y","article-title":"Polychoric versus Pearson correlations in exploratory and confirmatory factor analysis of ordinal variables.","volume":"44","author":"FP Holgado\u2013Tello","year":"2010","journal-title":"Quality & Quantity."},{"key":"pone.0258288.ref041","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1007\/BF02289447","article-title":"A RATIONALE AND TEST FOR THE NUMBER OF FACTORS IN FACTOR ANALYSIS.","volume":"30","author":"JL Horn","year":"1965","journal-title":"Psychometrika"},{"issue":"1","key":"pone.0258288.ref042","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1111\/j.2044-8317.1964.tb00244.x","article-title":"Promax: A quick method for rotation to oblique simple structure.","volume":"17","author":"AE Hendrickson","year":"1964","journal-title":"British journal of statistical psychology"},{"key":"pone.0258288.ref043","doi-asserted-by":"crossref","DOI":"10.4324\/9781410601087","volume-title":"Test Theory New York:","author":"R. McDonald","year":"2013"},{"issue":"2","key":"pone.0258288.ref044","first-page":"23","article-title":"Evaluating the fit of structural equation models: Tests of significance and descriptive goodness-of-fit measures.","volume":"8","author":"K Schermelleh-Engel","year":"2003","journal-title":"Methods of psychological research online."},{"issue":"4","key":"pone.0258288.ref045","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1177\/1757975915579800","article-title":"The theoretical model of the school-based prevention programme Unplugged.","volume":"23","author":"S Vadrucci","year":"2016","journal-title":"Glob Health Promot"},{"key":"pone.0258288.ref046","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.drugalcdep.2019.02.034","article-title":"Trends in binge drinking and alcohol abstention among adolescents in the US, 2002\u20132016.","volume":"200","author":"T Clark Goings","year":"2019","journal-title":"Drug Alcohol Depend."},{"key":"pone.0258288.ref047","doi-asserted-by":"crossref","DOI":"10.4324\/9780203771587","volume-title":"Statistical power analysis for the behavioral sciences","author":"J. Cohen","year":"2013"},{"issue":"3","key":"pone.0258288.ref048","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1037\/met0000144","article-title":"Thanks coefficient alpha, we\u2019ll take it from here.","volume":"23","author":"D. McNeish","year":"2018","journal-title":"Psychol Methods"},{"key":"pone.0258288.ref049","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/j.adolescence.2017.02.011","article-title":"Individual and contextual factors associated with tobacco, alcohol, and cannabis use among Chilean adolescents: A multilevel study.","volume":"56","author":"J Gaete","year":"2017","journal-title":"J Adolesc."},{"issue":"4","key":"pone.0258288.ref050","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1111\/nhs.12565","article-title":"Role of social normative beliefs as a moderating factor in smoking intention among adolescent girls in Korea.","volume":"20","author":"JS Ra","year":"2018","journal-title":"Nurs Health Sci"},{"issue":"4","key":"pone.0258288.ref051","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1080\/17437199.2011.587961","article-title":"The effect of peer influence and selection processes on adolescent alcohol use: a systematic review of longitudinal studies","volume":"8","author":"RK Leung","year":"2014","journal-title":"Health Psychol Rev"},{"issue":"1","key":"pone.0258288.ref052","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1007\/s11121-013-0384-8","article-title":"Youth misperceptions of peer substance use norms: a hidden risk factor in state and community prevention.","volume":"15","author":"RA Wambeam","year":"2014","journal-title":"Prev Sci"},{"issue":"2","key":"pone.0258288.ref053","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1002\/hec.705","article-title":"How measures of perception from survey data lead to inconsistent regression results: evidence from adolescent and peer substance use.","volume":"12","author":"EC Norton","year":"2003","journal-title":"Health Econ"},{"key":"pone.0258288.ref054","doi-asserted-by":"crossref","first-page":"111","DOI":"10.4103\/ijpvm.IJPVM_493_17","article-title":"Effectiveness of a Peer-Led Behavioral Intervention Program on Tobacco Use-Related Knowledge, Attitude, Normative Beliefs, and Intention to Smoke among Adolescents at Iranian Public High Schools.","volume":"10","author":"M Mohammadi","year":"2019","journal-title":"Int J Prev Med."},{"key":"pone.0258288.ref055","doi-asserted-by":"crossref","first-page":"25","DOI":"10.3389\/fpsyt.2018.00025","article-title":"Association between School Membership and Substance Use among Adolescents.","volume":"9","author":"J Gaete","year":"2018","journal-title":"Front Psychiatry."},{"issue":"6","key":"pone.0258288.ref056","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1016\/j.jadohealth.2018.07.002","article-title":"The Protective Effects of School Connectedness on Substance Use and Physical Activity","volume":"63","author":"KA Weatherson","year":"2018","journal-title":"Journal of Adolescent Health"},{"key":"pone.0258288.ref057","doi-asserted-by":"crossref","first-page":"106197","DOI":"10.1016\/j.ypmed.2020.106197","article-title":"The mediating role of school connectedness in the associations between dating and sexual violence victimization and substance use among high school students.","volume":"139","author":"MM Mulla","year":"2020","journal-title":"Preventive Medicine"},{"key":"pone.0258288.ref058","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.adolescence.2017.12.003","article-title":"Violence in Brazilian schools: Analysis of the effect of the #Tamojunto prevention program for bullying and physical violence.","volume":"63","author":"JDSP Gusm\u00f5es","year":"2018","journal-title":"Journal of Adolescence"},{"issue":"1","key":"pone.0258288.ref059","doi-asserted-by":"crossref","first-page":"e0208072","DOI":"10.1371\/journal.pone.0208072","article-title":"The role of normative beliefs in the mediation of a school-based drug prevention program: A secondary analysis of the #Tamojunto cluster-randomized trial.","volume":"14","author":"ZM Sanchez","year":"2019","journal-title":"PLoS One."},{"issue":"7","key":"pone.0258288.ref060","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1177\/0017896915612227","article-title":"What works in school-based alcohol education: A systematic review","volume":"75","author":"NK Lee","year":"2016","journal-title":"Health Education Journal"},{"issue":"4","key":"pone.0258288.ref061","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1037\/0021-843X.112.4.558","article-title":"Testing mediational models with longitudinal data: questions and tips in the use of structural equation modeling.","volume":"112","author":"DA Cole","year":"2003","journal-title":"J Abnorm Psychol"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0258288","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,10,11]],"date-time":"2021-10-11T19:54:16Z","timestamp":1633982056000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0258288"}},"subtitle":[],"editor":[{"given":"Zila M.","family":"Sanchez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2021,10,11]]},"references-count":61,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2021,10,11]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0258288","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,10,11]]}}}