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Limited knowledge exists on adolescent girls\u2019 aspirations and their determinants, particularly in low-income contexts.<\/jats:p><\/jats:sec><jats:sec id=\"sec002\"><jats:title>Methods and findings<\/jats:title><jats:p>Using cross-sectional data, collected in 2018 in Nepal, within the<jats:italic>Suaahara II<\/jats:italic>Adolescent Panel Survey, (n = 840), adolescent girls\u2019 aspirations in several domains\u2014education, occupation, marriage, fertility, health, and nutrition\u2013were described. Regression models were estimated to explore associations between individual, household and community characteristics and these aspirations for all adolescents and separately for younger (10\u201314 years) and older (15\u201319 years) girls. Age, school attendance, and self-efficacy, as well as household wealth, caste\/ethnicity, size, and agro-ecological zone of residence were significantly associated with aspirations, although effect sizes and significance varied by aspiration domain and age group.<\/jats:p><\/jats:sec><jats:sec id=\"sec003\"><jats:title>Conclusions<\/jats:title><jats:p>Findings underscore the curtailing effect of poverty on aspirations and the dynamic nature of aspirations. Initiatives to foster girls\u2019 aspirations must address both individual and contextual factors.<\/jats:p><\/jats:sec>","DOI":"10.1371\/journal.pone.0258416","type":"journal-article","created":{"date-parts":[[2021,11,12]],"date-time":"2021-11-12T18:23:07Z","timestamp":1636741387000},"page":"e0258416","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":9,"title":["Unravelling adolescent girls\u2019 aspirations in Nepal: Status and associations with individual-, household-, and community-level characteristics"],"prefix":"10.1371","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6137-1735","authenticated-orcid":true,"given":"D\u00f3nya S.","family":"Madjdian","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenda","family":"Cunningham","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hilde","family":"Bras","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria","family":"Koelen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lenneke","family":"Vaandrager","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ramesh P.","family":"Adhikari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elise F.","family":"Talsma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2021,11,12]]},"reference":[{"issue":"3","key":"pone.0258416.ref001","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/S2352-4642(18)30022-1","article-title":"The age of adolescence","volume":"2","author":"SM Sawyer","year":"2018","journal-title":"The Lancet Child & Adolescent Health"},{"key":"pone.0258416.ref002","unstructured":"United Nations, Department of Economic and Social Affairs, Population Division. 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