{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T21:23:14Z","timestamp":1783632194852,"version":"3.55.0"},"reference-count":27,"publisher":"Public Library of Science (PLoS)","issue":"11","license":[{"start":{"date-parts":[[2021,11,4]],"date-time":"2021-11-04T00:00:00Z","timestamp":1635984000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\">\n<jats:title>Study objective<\/jats:title>\n<jats:p>The main objective of this study is to test the feasibility of the local anesthetic (LA) Mepivacaine 1% and sedation with Remifentanil as the primary anesthetic technique for the insertion of a peritoneal dialysis (PD) catheter, without the need to convert to general anesthesia.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec002\">\n<jats:title>Methods<\/jats:title>\n<jats:p>We analyzed 27 consecutive end-stage renal disease (ESRD) patients who underwent the placement of a peritoneal catheter at our center between March 2015 and January 2019. The procedures were all performed by a general or vascular surgeon, and the postoperative care and follow-up were all conducted by the same peritoneal dialysis team.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec003\">\n<jats:title>Results<\/jats:title>\n<jats:p>All of the 27 subjects successfully underwent the procedure without the need of conversion to general anesthesia. The catheter was deemed prone to usage in all patients and was found to be leak-proof in 100% of the patients.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec004\">\n<jats:title>Conclusion<\/jats:title>\n<jats:p>This study describes a safe and successful approach for insertion of a PD catheter by combined infiltration of the local anesthetic Mepivacaine 1% and sedation with Remifentanil. Hereby, ESRD patients can be treated without general anesthesia, while ensuring functionality of the PD catheter.<\/jats:p>\n<\/jats:sec>","DOI":"10.1371\/journal.pone.0259351","type":"journal-article","created":{"date-parts":[[2021,11,4]],"date-time":"2021-11-04T17:33:22Z","timestamp":1636047202000},"page":"e0259351","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":4,"title":["Implantation of a peritoneal dialysis catheter in patients with ESRD using local anesthesia and Remifentanil"],"prefix":"10.1371","volume":"16","author":[{"given":"Elizabeth","family":"Jabbour","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carsten","family":"F\u00fctterer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebastian","family":"Zach","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna-Isabelle","family":"K\u00e4lsch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Keese","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nuh N.","family":"Rahbari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernhard K.","family":"Kr\u00e4mer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4242-3602","authenticated-orcid":true,"given":"Kay G.","family":"Schwenke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2021,11,4]]},"reference":[{"key":"pone.0259351.ref001","article-title":"Global Trends in Rates of Peritoneal Dialysis","author":"A. 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Selby","year":"2019","journal-title":"Semin. Dial."},{"key":"pone.0259351.ref005","first-page":"2000","article-title":"G, Peritoneal dialysis: Its indications and contraindications","volume":"77","author":"A Shetty","journal-title":"Dialysis and Transplantation. 29. 71"},{"issue":"3","key":"pone.0259351.ref006","first-page":"334","article-title":"Hemodialysis Versus Peritoneal Dialysis: A Comparison","volume":"30","author":"S. S. a Fenton","year":"1997"},{"issue":"4","key":"pone.0259351.ref007","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1159\/000182882","article-title":"The Tenckhoff catheter for peritoneal dialysis\u2013an appraisal","volume":"32","author":"J Rubin","year":"1982","journal-title":"Nephron"},{"issue":"5","key":"pone.0259351.ref008","doi-asserted-by":"crossref","first-page":"513","DOI":"10.3747\/pdi.2009.00033","article-title":"Mini-laparotomy implantation of peritoneal dialysis catheters: Outcome and rescue","volume":"30","author":"P. J. 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