{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T04:18:48Z","timestamp":1791346728722,"version":"4.3.1"},"reference-count":51,"publisher":"Public Library of Science (PLoS)","issue":"1","license":[{"start":{"date-parts":[[2022,1,21]],"date-time":"2022-01-21T00:00:00Z","timestamp":1642723200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Ministry of Foreign Affairs of Denmark, administered by Danida Fellowship Centre, Denmark","award":["16-PO1-TAN"],"award-info":[{"award-number":["16-PO1-TAN"]}]},{"name":"Centre of Physical activity Research, TrygFonden, Denmark","award":["101390 and 20045"],"award-info":[{"award-number":["101390 and 20045"]}]},{"name":"UK Medical Research and NIHR Biomedical Research Centre, UK","award":["IS-BRC-1215-20014"],"award-info":[{"award-number":["IS-BRC-1215-20014"]}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01HL160332"],"award-info":[{"award-number":["R01HL160332"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Ministry of Foreign Affairs of Denmark, administered by Danida Fellowship Centre, Denmark","award":["16-P01-TAN"],"award-info":[{"award-number":["16-P01-TAN"]}]},{"name":"Ministry of Foreign Affairs of Denmark, administered by Danida Fellowship Centre, Denmark","award":["16-P01-TAN"],"award-info":[{"award-number":["16-P01-TAN"]}]},{"name":"Ministry of Foreign Affairs of Denmark, administered by Danida Fellowship Centre, Denmark","award":["16-P01-TAN"],"award-info":[{"award-number":["16-P01-TAN"]}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\">\n<jats:title>Introduction<\/jats:title>\n<jats:p>In the HIV-infected individuals, physical activity improves physical strength, quality of life and reduces the risk of developing non-communicable diseases. In Sub-Saharan Africa, HIV-infected patients report being less active compared to HIV-uninfected individuals. We assessed the levels and correlates of objectively measured physical activity and capacity among HIV-infected antiretroviral therapy (ART)-naive individuals compared to HIV-uninfected individuals in Mwanza, Tanzania.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec002\">\n<jats:title>Method<\/jats:title>\n<jats:p>We conducted a cross-sectional study among newly diagnosed HIV-infected ART-naive individuals and HIV-uninfected individuals frequency-matched for age and sex. Socio-demographic data, anthropometrics, CD4 counts, haemoglobin level, and C-reactive protein (CRP) were collected. Physical activity energy expenditure (PAEE) was assessed as measure of physical activity whereas sleeping heart rate (SHR) and grip strength were assessed as measures of physical capacity. Multivariable linear regression was used to assess the correlates associated with physical activity and capacity.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec003\">\n<jats:title>Results<\/jats:title>\n<jats:p>A total of 272 HIV-infected and 119 HIV-uninfected individuals, mean age 39 years and 60% women participated in the study. Compared to HIV-uninfected individuals, HIV-infected had poorer physical activity and capacity: lower PAEE (-7.3 kj\/kg\/day, 95% CI: -11.2, -3.3), elevated SHR (7.7 beats\/min, 95%CI: 10.1, 5.3) and reduced grip strength (-4.7 kg, 95%CI: -6.8, -2.8). In HIV-infected individuals, low body mass index, moderate-severe anaemia, low CD4 counts and high CRP were associated with lower physical activity and capacity. In HIV-uninfected individuals, abdominal obesity and moderate anaemia were associated with lower physical activity and capacity.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec004\">\n<jats:title>Conclusion<\/jats:title>\n<jats:p>HIV-infected participants had lower levels of physical activity and capacity than HIV-uninfected participants. Correlates of physical activity and capacity differed by HIV status. Management of HIV and related conditions needs to be provided effectively in health care facilities. Interventions promoting physical activity in these populations will be of importance to improve their health and reduce the risk of non-communicable diseases.<\/jats:p>\n<\/jats:sec>","DOI":"10.1371\/journal.pone.0262298","type":"journal-article","created":{"date-parts":[[2022,1,21]],"date-time":"2022-01-21T18:42:22Z","timestamp":1642790542000},"page":"e0262298","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":21,"title":["Levels and correlates of physical activity and capacity among HIV-infected compared to HIV-uninfected individuals"],"prefix":"10.1371","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0734-5944","authenticated-orcid":true,"given":"Brenda","family":"Kitilya","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George","family":"PrayGod","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Peck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Changalucha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kidola","family":"Jeremiah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4839-4590","authenticated-orcid":true,"given":"Bazil Baltazar","family":"Kavishe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henrik","family":"Friis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suzanne","family":"Filteau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Faurholt-Jepsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rikke","family":"Krogh-Madsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1265-7355","authenticated-orcid":true,"given":"Soren","family":"Brage","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5742-6403","authenticated-orcid":true,"given":"Mette F.","family":"Olsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2022,1,21]]},"reference":[{"issue":"10113","key":"pone.0262298.ref001","doi-asserted-by":"crossref","first-page":"2643","DOI":"10.1016\/S0140-6736(17)31634-3","article-title":"The effect of physical activity on mortality and cardiovascular disease in 130 000 people from 17 high-income, middle-income, and low-income countries: the PURE study","volume":"390","author":"SA Lear","year":"2017","journal-title":"Lancet (London, England)"},{"issue":"2","key":"pone.0262298.ref002","first-page":"CD001796","article-title":"Aerobic exercise interventions for adults living with HIV\/AIDS","author":"S Nixon","year":"2005","journal-title":"The Cochrane database of systematic reviews"},{"key":"pone.0262298.ref003","doi-asserted-by":"crossref","first-page":"80","DOI":"10.2174\/1874613601509010080","article-title":"Effects of a 2-Year Supervised Exercise Program Upon the Body Composition and Muscular Performance of HIV-Infected Patients","volume":"9","author":"S Paes Lda","year":"2015","journal-title":"The open AIDS journal"},{"issue":"4","key":"pone.0262298.ref004","first-page":"CD004248","article-title":"Progressive resistive exercise interventions for adults living with HIV\/AIDS","author":"K O\u2019Brien","year":"2004","journal-title":"The Cochrane database of systematic reviews"},{"issue":"5","key":"pone.0262298.ref005","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1111\/tmi.12852","article-title":"Physical function, grip strength and frailty in people living with HIV in sub-Saharan Africa: systematic review","volume":"22","author":"C Bernard","year":"2017","journal-title":"Trop Med Int Health"},{"issue":"9","key":"pone.0262298.ref006","first-page":"1013","article-title":"Physical impairment in HIV infections and AIDS: responses to resistance and aerobic training","volume":"55","author":"RJ Shephard","year":"2015","journal-title":"The Journal of sports medicine and physical fitness"},{"issue":"8","key":"pone.0262298.ref007","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.1080\/09540121.2016.1274016","article-title":"High prevalence of physical inactivity among patients from the Swiss HIV Cohort Study","volume":"29","author":"J Schafer","year":"2017","journal-title":"AIDS care"},{"issue":"6","key":"pone.0262298.ref008","doi-asserted-by":"crossref","first-page":"487","DOI":"10.2174\/157016212802429794","article-title":"Physical activity: do patients infected with HIV practice? How much? A systematic review","volume":"10","author":"F Schuelter-Trevisol","year":"2012","journal-title":"Current HIV research"},{"issue":"1","key":"pone.0262298.ref009","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1186\/s12879-017-2209-z","article-title":"Dysglycemia associations with adipose tissue among HIV-infected patients after 2 years of antiretroviral therapy in Mwanza: a follow-up cross-sectional study","volume":"17","author":"G PrayGod","year":"2017","journal-title":"BMC infectious diseases"},{"issue":"3\u20134","key":"pone.0262298.ref010","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1080\/17290376.2014.886081","article-title":"The physical activity levels among people living with human immunodeficiency virus\/acquired immunodeficiency syndrome receiving high active antiretroviral therapy in Rwanda","volume":"10","author":"JM Frantz","year":"2013","journal-title":"SAHARA J: journal of Social Aspects of HIV\/AIDS Research Alliance"},{"issue":"1","key":"pone.0262298.ref011","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1186\/s12889-017-4512-4","article-title":"Physical activity and associated factors from a cross-sectional survey among adults in northern Tanzania","volume":"17","author":"B John","year":"2017","journal-title":"BMC public health"},{"issue":"9","key":"pone.0262298.ref012","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1123\/jpah.2015-0631","article-title":"Physical Activity Levels Among Adults in Uganda: Findings From a Countrywide Cross-Sectional Survey","volume":"13","author":"D Guwatudde","year":"2016","journal-title":"Journal of physical activity & health"},{"key":"pone.0262298.ref013","doi-asserted-by":"crossref","first-page":"5","DOI":"10.3389\/fnut.2014.00005","article-title":"Assessment of physical activity and energy expenditure: an overview of objective measures","volume":"1","author":"AP Hills","year":"2014","journal-title":"Frontiers in nutrition"},{"issue":"1","key":"pone.0262298.ref014","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1123\/jpah.8.1.62","article-title":"Self-report vs. objectively assessed physical activity: which is right for public health?","volume":"8","author":"T Loney","year":"2011","journal-title":"Journal of physical activity & health"},{"issue":"sup2","key":"pone.0262298.ref015","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1080\/02701367.2000.11082782","article-title":"Objective Monitoring of Physical Activity Using Motion Sensors and Heart Rate","volume":"71","author":"PS Freedson","year":"2000","journal-title":"Research Quarterly for Exercise and Sport"},{"issue":"1","key":"pone.0262298.ref016","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1152\/japplphysiol.00703.2003","article-title":"Branched equation modeling of simultaneous accelerometry and heart rate monitoring improves estimate of directly measured physical activity energy expenditure","volume":"96","author":"S Brage","year":"2004","journal-title":"Journal of applied physiology (Bethesda, Md: 1985)"},{"issue":"8","key":"pone.0262298.ref017","doi-asserted-by":"crossref","first-page":"7772","DOI":"10.3390\/s100807772","article-title":"A review of accelerometry-based wearable motion detectors for physical activity monitoring","volume":"10","author":"CC Yang","year":"2010","journal-title":"Sensors (Basel, Switzerland)"},{"issue":"1","key":"pone.0262298.ref018","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1186\/s12966-016-0351-4","article-title":"Should we reframe how we think about physical activity and sedentary behaviour measurement? Validity and reliability reconsidered","volume":"13","author":"P Kelly","year":"2016","journal-title":"International Journal of Behavioral Nutrition and Physical Activity"},{"issue":"1","key":"pone.0262298.ref019","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1093\/ije\/dyq098","article-title":"Accuracy and validity of a combined heart rate and motion sensor for the measurement of free-living physical activity energy expenditure in adults in Cameroon","volume":"40","author":"FK Assah","year":"2011","journal-title":"International journal of epidemiology"},{"issue":"5","key":"pone.0262298.ref020","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1097\/MCO.0000000000000202","article-title":"Muscle strength: clinical and prognostic value of hand-grip dynamometry","volume":"18","author":"RW Bohannon","year":"2015","journal-title":"Current Opinion in Clinical Nutrition & Metabolic Care"},{"key":"pone.0262298.ref021","article-title":"Resting heart rate as a biomarker for tracking change in cardiorespiratory fitness of UK adults: The Fenland Study","author":"TI Gonzales","year":"2020","journal-title":"medRxiv"},{"issue":"6","key":"pone.0262298.ref022","doi-asserted-by":"crossref","first-page":"1334","DOI":"10.1017\/S0950268813002070","article-title":"The use of combined heart rate response and accelerometry to assess the level and predictors of physical activity in tuberculosis patients in Tanzania","volume":"142","author":"M Faurholt-Jepsen","year":"2014","journal-title":"Epidemiology and infection"},{"issue":"2","key":"pone.0262298.ref023","doi-asserted-by":"crossref","first-page":"394","DOI":"10.4314\/ahs.v18i2.25","article-title":"Physical activity and HIV in sub-Saharan Africa: a systematic review of correlates and levels","volume":"18","author":"D Vancampfort","year":"2018","journal-title":"African health sciences"},{"issue":"5","key":"pone.0262298.ref024","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1017\/S0950268814001502","article-title":"Physical activity and capacity at initiation of antiretroviral treatment in HIV patients in Ethiopia","volume":"143","author":"MF Olsen","year":"2015","journal-title":"Epidemiology and infection"},{"key":"pone.0262298.ref025","unstructured":"Tanzania HIV Impact Survey report 2016\/2017. Tanzania Commission for AIDS; Dar-es-salaam, Tanzania: 2017."},{"issue":"4","key":"pone.0262298.ref026","doi-asserted-by":"crossref","first-page":"e0230723","DOI":"10.1371\/journal.pone.0230723","article-title":"Diabetes prevalence by HbA1c and oral glucose tolerance test among HIV-infected and uninfected Tanzanian adults","volume":"15","author":"K Jeremiah","year":"2020","journal-title":"PloS one"},{"issue":"5","key":"pone.0262298.ref027","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1017\/S0950268814001502","article-title":"Physical activity and capacity at initiation of antiretroviral treatment in HIV patients in Ethiopia","volume":"143","author":"MF Olsen","year":"2015","journal-title":"Epidemiology and infection"},{"key":"pone.0262298.ref028","unstructured":"Tanzania Multisectoral Strategic Framework for HIV and AIDS 2018\u20132023 p.80: Tanzania commision for AIDS(TACAIDS); Dar-es-salaam, Tanzania: 2018."},{"issue":"4","key":"pone.0262298.ref029","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1038\/sj.ejcn.1602118","article-title":"Reliability and validity of the combined heart rate and movement sensor Actiheart","volume":"59","author":"S Brage","year":"2005","journal-title":"Eur J Clin Nutr"},{"issue":"2","key":"pone.0262298.ref030","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1152\/japplphysiol.00092.2006","article-title":"Hierarchy of individual calibration levels for heart rate and accelerometry to measure physical activity","volume":"103","author":"S Brage","year":"2007","journal-title":"Journal of applied physiology (Bethesda, Md: 1985)"},{"issue":"9","key":"pone.0262298.ref031","doi-asserted-by":"crossref","first-page":"2143","DOI":"10.1109\/TBME.2008.923118","article-title":"Gaussian process robust regression for noisy heart rate data","volume":"55","author":"O Stegle","year":"2008","journal-title":"IEEE transactions on bio-medical engineering"},{"issue":"11","key":"pone.0262298.ref032","doi-asserted-by":"crossref","first-page":"3127","DOI":"10.1093\/jn\/134.11.3127","article-title":"Combined measurement of ferritin, soluble transferrin receptor, retinol binding protein, and C-reactive protein by an inexpensive, sensitive, and simple sandwich enzyme-linked immunosorbent assay technique","volume":"134","author":"JG Erhardt","year":"2004","journal-title":"The Journal of nutrition"},{"key":"pone.0262298.ref033","unstructured":"WHO. Haemoglobin concentrations fpr the diagnosis of anaemia and assessmentof severity, Vitamin and mineral nutrition information system Geneva, switzerland: 2011."},{"key":"pone.0262298.ref034","unstructured":"WHO. Waist circumference and Waist -Hip ratio, Report of WHO Expert consultation. Geneva, Switzerland: December, 2008."},{"issue":"2","key":"pone.0262298.ref035","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1056\/NEJM199507133330202","article-title":"Energy expenditure and wasting in human immunodeficiency virus infection","volume":"333","author":"DC Macallan","year":"1995","journal-title":"The New England journal of medicine"},{"issue":"6","key":"pone.0262298.ref036","doi-asserted-by":"crossref","first-page":"1677S","DOI":"10.3945\/ajcn.111.012625","article-title":"Energy expenditure in HIV infection","volume":"94","author":"L. Kosmiski","year":"2011","journal-title":"Am J Clin Nutr"},{"issue":"3","key":"pone.0262298.ref037","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1016\/j.jand.2017.12.007","article-title":"Practice Paper of the Academy of Nutrition and Dietetics: Nutrition Intervention and Human Immunodeficiency Virus Infection","volume":"118","author":"A Willig","year":"2018","journal-title":"Journal of the Academy of Nutrition and Dietetics"},{"issue":"1","key":"pone.0262298.ref038","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1186\/s12963-017-0128-2","article-title":"Prevalence and risk factors for anemia severity and type in Malawian men and women: urban and rural differences","volume":"15","author":"AL Adamu","year":"2017","journal-title":"Population Health Metrics"},{"issue":"1","key":"pone.0262298.ref039","doi-asserted-by":"crossref","first-page":"3860","DOI":"10.1186\/s12879-014-0702-1","article-title":"Resolution of anaemia in a cohort of HIV-infected patients with a high prevalence and incidence of tuberculosis receiving antiretroviral therapy in South Africa","volume":"14","author":"AD Kerkhoff","year":"2014","journal-title":"BMC infectious diseases"},{"issue":"4","key":"pone.0262298.ref040","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1139\/h2012-044","article-title":"Relationship between physical activity, physical performance, and iron status in adult women","volume":"37","author":"SE Crouter","year":"2012","journal-title":"Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme"},{"issue":"2","key":"pone.0262298.ref041","doi-asserted-by":"crossref","first-page":"594S","DOI":"10.1093\/ajcn\/72.2.594S","article-title":"Iron status and exercise","volume":"72","author":"J Beard","year":"2000","journal-title":"The American Journal of Clinical Nutrition"},{"issue":"1","key":"pone.0262298.ref042","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1186\/s13643-018-0927-y","article-title":"Prevalence of metabolic syndrome among HIV-positive and HIV-negative populations in sub-Saharan Africa-a systematic review and meta-analysis","volume":"8","author":"OO Todowede","year":"2019","journal-title":"Systematic reviews"},{"key":"pone.0262298.ref043","doi-asserted-by":"crossref","first-page":"6123156","DOI":"10.1155\/2018\/6123156","article-title":"The Prevalence of Abdominal Obesity and Its Correlates among the Adults in Dodoma Region, Tanzania: A Community-Based Cross-Sectional Study","volume":"2018","author":"MJ Munyogwa","year":"2018","journal-title":"Advances in Medicine"},{"issue":"4","key":"pone.0262298.ref044","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1345\/aph.17072","article-title":"HIV Wasting Syndrome: Treatment Update","volume":"32","author":"DL Balog","year":"1998","journal-title":"Annals of Pharmacotherapy"},{"issue":"4","key":"pone.0262298.ref045","doi-asserted-by":"crossref","first-page":"S313","DOI":"10.1177\/15648265100314S403","article-title":"Role of nutrition in HIV infection: review of evidence for more effective programming in resource-limited settings","volume":"31","author":"S de Pee","year":"2010","journal-title":"Food and nutrition bulletin"},{"issue":"3","key":"pone.0262298.ref046","first-page":"445","article-title":"Long-term impact of HIV wasting on physical function","volume":"30","author":"KM Erlandson","year":"2016","journal-title":"AIDS (London, England)"},{"issue":"14","key":"pone.0262298.ref047","doi-asserted-by":"crossref","first-page":"1618","DOI":"10.1080\/09638288.2017.1306587","article-title":"Physical activity correlates in people living with HIV\/AIDS: a systematic review of 45 studies","volume":"40","author":"D Vancampfort","year":"2018","journal-title":"Disability and rehabilitation"},{"issue":"3","key":"pone.0262298.ref048","doi-asserted-by":"crossref","first-page":"E53","DOI":"10.1503\/cmaj.150535","article-title":"Resting heart rate and all-cause and cardiovascular mortality in the general population: a meta-analysis","volume":"188","author":"D Zhang","year":"2016","journal-title":"CMAJ: Canadian Medical Association journal = journal de l\u2019Association medicale canadienne"},{"issue":"2","key":"pone.0262298.ref049","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1097\/HJR.0b013e32832ed875","article-title":"Assessment of physical activity\u2014a review of methodologies with reference to epidemiological research: a report of the exercise physiology section of the European Association of Cardiovascular Prevention and Rehabilitation","volume":"17","author":"JM Warren","year":"2010","journal-title":"European journal of cardiovascular prevention and rehabilitation: official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology"},{"issue":"1","key":"pone.0262298.ref050","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1186\/s12966-017-0636-2","article-title":"A systematic literature review of reviews on techniques for physical activity measurement in adults: a DEDIPAC study","volume":"15","author":"KP Dowd","year":"2018","journal-title":"The international journal of behavioral nutrition and physical activity"},{"issue":"9","key":"pone.0262298.ref051","doi-asserted-by":"crossref","first-page":"e0137206","DOI":"10.1371\/journal.pone.0137206","article-title":"Estimation of Free-Living Energy Expenditure by Heart Rate and Movement Sensing: A Doubly-Labelled Water Study","volume":"10","author":"S Brage","year":"2015","journal-title":"PloS one"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0262298","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,21]],"date-time":"2022-01-21T18:43:20Z","timestamp":1642790600000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0262298"}},"subtitle":[],"editor":[{"given":"Elizabeth S.","family":"Mayne","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2022,1,21]]},"references-count":51,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2022,1,21]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0262298","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,1,21]]}}}