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This study aims to fill the gap in risk modeling of COVID-19 outbreaks in facilities like offices and warehouses. We propose a simulation-based stochastic contact network model to assess the cumulative incidence in workplaces. First-generation cases are introduced as a Bernoulli random variable using the local daily new case rate as the success rate. Contact networks are established through randomly sampled daily contacts for each of the first-generation cases and successful transmissions are established based on a randomized secondary attack rate (SAR). Modification factors are provided for SAR based on changes in airflow, speaking volume, and speaking activity within a facility. Control measures such as mask wearing are incorporated through modifications in SAR. We validated the model by comparing the distribution of cumulative incidence in model simulations against real-world outbreaks in workplaces and nursing homes. The comparisons support the model\u2019s validity for estimating cumulative incidences for short forecasting periods of up to 15 days. We believe that the current study presents an effective tool for providing short-term forecasts of COVID-19 cases for workplaces and for quantifying the effectiveness of various control measures. The open source model code is made available at github.com\/abhineetgupta\/covid-workplace-risk.<\/jats:p>","DOI":"10.1371\/journal.pone.0262316","type":"journal-article","created":{"date-parts":[[2022,1,14]],"date-time":"2022-01-14T19:33:26Z","timestamp":1642188806000},"page":"e0262316","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":4,"title":["A stochastic contact network model for assessing outbreak risk of COVID-19 in workplaces"],"prefix":"10.1371","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1925-3142","authenticated-orcid":true,"given":"Xi","family":"Guo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abhineet","family":"Gupta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3409-6827","authenticated-orcid":true,"given":"Anand","family":"Sampat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8508-9838","authenticated-orcid":true,"given":"Chengwei","family":"Zhai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2022,1,14]]},"reference":[{"key":"pone.0262316.ref001","unstructured":"Ritchie H, Ortiz-Ospina E, Beltekian D, Mathieu E, Hasell J, Macdonald B, et al. Coronavirus Pandemic (COVID-19); 2021. Available from: https:\/\/ourworldindata.org\/coronavirus."},{"issue":"9","key":"pone.0262316.ref002","doi-asserted-by":"crossref","first-page":"e238","DOI":"10.1016\/S1473-3099(20)30484-9","article-title":"Comparing SARS-CoV-2 with SARS-CoV and influenza pandemics","volume":"20","author":"E Petersen","year":"2020","journal-title":"The Lancet Infectious Diseases"},{"key":"pone.0262316.ref003","unstructured":"Sternlicht A. Over 10,000 Tyson Employees Reportedly Test Positive For Covid. Forbes. 2020;."},{"key":"pone.0262316.ref004","unstructured":"Bradbury S. How coronavirus spread through JBS\u2019s Greeley beef plant. The Denver Post. 2020;."},{"issue":"31","key":"pone.0262316.ref005","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.15585\/mmwr.mm6931a2","article-title":"COVID-19 Outbreak Among Employees at a Meat Processing Facility\u2014South Dakota, March-April 2020","volume":"69","author":"J Steinberg","year":"2020","journal-title":"MMWR Morbidity and Mortality Weekly Report"},{"key":"pone.0262316.ref006","unstructured":"Lerman R. Amazon says nearly 20,000 employees have caught the coronavirus. 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Available from: https:\/\/www.microcovid.org\/."},{"issue":"12","key":"pone.0262316.ref027","doi-asserted-by":"crossref","first-page":"1313","DOI":"10.1038\/s41562-020-01000-9","article-title":"Real-time, interactive website for US-county-level COVID-19 event risk assessment","volume":"4","author":"A Chande","year":"2020","journal-title":"Nature Human Behaviour"},{"issue":"1","key":"pone.0262316.ref028","doi-asserted-by":"crossref","first-page":"2547","DOI":"10.1038\/s41598-021-81814-3","article-title":"The effect of the definition of \u201cpandemic\u201d on quantitative assessments of infectious disease outbreak risk","volume":"11","author":"BJ Singer","year":"2021","journal-title":"Scientific Reports"},{"issue":"4","key":"pone.0262316.ref029","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1007\/s10682-011-9526-2","article-title":"Community structure and the spread of infectious disease in primate social networks","volume":"26","author":"RH Griffin","year":"2012","journal-title":"Evolutionary Ecology"},{"issue":"15","key":"pone.0262316.ref030","doi-asserted-by":"crossref","first-page":"1297","DOI":"10.1016\/j.scib.2020.04.043","article-title":"Using the contact network model and Metropolis-Hastings sampling to reconstruct the COVID-19 spread on the \u201cDiamond Princess\u201d","volume":"65","author":"F Liu","year":"2020","journal-title":"Science Bulletin"},{"key":"pone.0262316.ref031","doi-asserted-by":"crossref","unstructured":"Mentus C, Romeo M, DiPaola C. 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Analysis of SARS-CoV-2 transmission in different settings, among cases and close contacts from the Tablighi cluster in Brunei Darussalam. medRxiv. 2020; p. 2020.05.04.20090043.","DOI":"10.1101\/2020.05.04.20090043"},{"key":"pone.0262316.ref052","doi-asserted-by":"crossref","unstructured":"Cheng HY, Jian SW, Liu DP, Ng TC, Huang WT, Team fTCoi, et al. High transmissibility of COVID-19 near symptom onset. medRxiv. 2020; p. 2020.03.18.20034561.","DOI":"10.1101\/2020.03.18.20034561"},{"key":"pone.0262316.ref053","doi-asserted-by":"crossref","unstructured":"Klepac P, Kucharski AJ, Conlan AJ, Kissler S, Tang ML, Fry H, et al. 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COVID-19 Nursing Home Dataset; 2021. Available from: https:\/\/data.cms.gov\/Special-Programs-Initiatives-COVID-19-Nursing-Home\/COVID-19-Nursing-Home-Dataset\/s2uc-8wxp."},{"issue":"311","key":"pone.0262316.ref063","first-page":"12","article-title":"An Overview of Nursing Home Facilities: Data from the 1997 National Nursing Home Survey","author":"CS Gabrel","year":"2000","journal-title":"Advance Data"},{"key":"pone.0262316.ref064","article-title":"COVID-19 testing problems started early, U.S. still playing from behind","author":"K Ketchum","year":"2020","journal-title":"Modern Healthcare"},{"key":"pone.0262316.ref065","unstructured":"American Society of Microbiology (ASM). Supply Shortages Impacting COVID-19 and Non-COVID Testing; 2021. Available from: https:\/\/asm.org\/Articles\/2020\/September\/Clinical-Microbiology-Supply-Shortage-Collecti-1."},{"issue":"7809","key":"pone.0262316.ref066","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1038\/s41586-020-2196-x","article-title":"Virological assessment of hospitalized patients with COVID-2019","volume":"581","author":"R W\u00f6lfel","year":"2020","journal-title":"Nature"},{"key":"pone.0262316.ref067","doi-asserted-by":"crossref","unstructured":"Ferretti L, Ledda A, Wymant C, Zhao L, Ledda V, Abeler L, et al. The timing of COVID-19 transmission. medRxiv. 2020; p. 20.","DOI":"10.1101\/2020.09.04.20188516"},{"issue":"4","key":"pone.0262316.ref068","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/S1473-3099(20)30113-4","article-title":"Viral load of SARS-CoV-2 in clinical samples","volume":"20","author":"Y Pan","year":"2020","journal-title":"The Lancet Infectious Diseases"},{"issue":"5","key":"pone.0262316.ref069","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1038\/s41591-020-0869-5","article-title":"Temporal dynamics in viral shedding and transmissibility of COVID-19","volume":"26","author":"X He","year":"2020","journal-title":"Nature Medicine"},{"key":"pone.0262316.ref070","first-page":"7889","article-title":"Transmission mode associated with coronavirus disease 2019: A review","volume":"24","author":"F Vella","year":"2020","journal-title":"European review for medical and pharmacological sciences"},{"issue":"10","key":"pone.0262316.ref071","doi-asserted-by":"crossref","first-page":"1798","DOI":"10.1007\/s42399-020-00498-4","article-title":"COVID-19 and its Modes of Transmission","volume":"2","author":"R Karia","year":"2020","journal-title":"SN Comprehensive Clinical Medicine"},{"issue":"1","key":"pone.0262316.ref072","doi-asserted-by":"crossref","first-page":"19589","DOI":"10.1038\/s41598-020-76442-2","article-title":"Long-distance airborne dispersal of SARS-CoV-2 in COVID-19 wards","volume":"10","author":"K Nissen","year":"2020","journal-title":"Scientific Reports"},{"issue":"8","key":"pone.0262316.ref073","doi-asserted-by":"crossref","first-page":"2932","DOI":"10.3390\/ijerph17082932","article-title":"Airborne Transmission Route of COVID-19: Why 2 Meters\/6 Feet of Inter-Personal Distance Could Not Be Enough","volume":"17","author":"L Setti","year":"2020","journal-title":"International Journal of Environmental Research and Public Health"},{"key":"pone.0262316.ref074","doi-asserted-by":"crossref","first-page":"105730","DOI":"10.1016\/j.envint.2020.105730","article-title":"Airborne transmission of SARS-CoV-2: The world should face the reality","volume":"139","author":"L Morawska","year":"2020","journal-title":"Environment International"},{"key":"pone.0262316.ref075","doi-asserted-by":"crossref","DOI":"10.1111\/INA.12766\/v2\/response1","article-title":"Indoor transmission of SARS-CoV-2","author":"H Qian","year":"2020","journal-title":"Indoor Air"},{"key":"pone.0262316.ref076","doi-asserted-by":"crossref","first-page":"110612","DOI":"10.1016\/j.envres.2020.110612","article-title":"A systematic review of possible airborne transmission of the COVID-19 virus (SARS-CoV-2) in the indoor air environment","volume":"193","author":"Z Noorimotlagh","year":"2021","journal-title":"Environmental Research"},{"issue":"8","key":"pone.0262316.ref077","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2015482118","article-title":"Mechanistic transmission modeling of COVID-19 on the Diamond Princess cruise ship demonstrates the importance of aerosol transmission","volume":"118","author":"P Azimi","year":"2021","journal-title":"Proceedings of the National Academy of Sciences"},{"issue":"2","key":"pone.0262316.ref078","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/j.pulmoe.2020.05.015","article-title":"Evaluating the massive underreporting and undertesting of COVID-19 cases in multiple global epicenters","volume":"27","author":"H Lau","year":"2021","journal-title":"Pulmonology"},{"key":"pone.0262316.ref079","doi-asserted-by":"crossref","first-page":"102378","DOI":"10.1016\/j.healthplace.2020.102378","article-title":"Longitudinal analyses of the relationship between development density and the COVID-19 morbidity and mortality rates: Early evidence from 1,165 metropolitan counties in the United States","volume":"64","author":"S Hamidi","year":"2020","journal-title":"Health & Place"},{"key":"pone.0262316.ref080","unstructured":"University of Colorado Health. Testing for COVID-19; 2020. Available from: https:\/\/www.uchealth.org\/services\/infectious-diseases\/coronavirus-covid-19\/covid-19-testing\/."},{"key":"pone.0262316.ref081","unstructured":"Labcorp. How to Get My COVID-19 Test Result; 2021. Available from: https:\/\/www.labcorp.com\/coronavirus-disease-covid-19\/individuals\/test-results."},{"key":"pone.0262316.ref082","article-title":"Estimating the extent of asymptomatic COVID-19 and its potential for community transmission: Systematic review and meta-analysis","author":"O Byambasuren","year":"2020","journal-title":"Official Journal of the Association of Medical Microbiology and Infectious Disease Canada"},{"key":"pone.0262316.ref083","doi-asserted-by":"crossref","first-page":"m4851","DOI":"10.1136\/bmj.m4851","article-title":"Asymptomatic transmission of covid-19","volume":"371","author":"AM Pollock","year":"2020","journal-title":"BMJ"},{"issue":"23","key":"pone.0262316.ref084","doi-asserted-by":"crossref","first-page":"10007","DOI":"10.1021\/acs.jpclett.0c02765","article-title":"Decoding Asymptomatic COVID-19 Infection and Transmission","volume":"11","author":"R Wang","year":"2020","journal-title":"The Journal of Physical Chemistry Letters"},{"issue":"3","key":"pone.0262316.ref085","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1016\/j.jmii.2020.02.012","article-title":"Asymptomatic carrier state, acute respiratory disease, and pneumonia due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2): Facts and myths","volume":"53","author":"CC Lai","year":"2020","journal-title":"Journal of Microbiology, Immunology, and Infection = Wei Mian Yu Gan Ran Za Zhi"},{"issue":"1","key":"pone.0262316.ref086","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.1080\/21505594.2020.1802194","article-title":"Characteristics of asymptomatic COVID-19 infection and progression: A multicenter, retrospective study","volume":"11","author":"C Yu","year":"2020","journal-title":"Virulence"},{"key":"pone.0262316.ref087","doi-asserted-by":"crossref","first-page":"100166","DOI":"10.1016\/j.onehlt.2020.100166","article-title":"The time serial distribution and influencing factors of asymptomatic COVID-19 cases in Hong Kong","volume":"10","author":"J Tao","year":"2020","journal-title":"One Health"},{"issue":"1","key":"pone.0262316.ref088","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.cell.2020.11.020","article-title":"Evaluating the Effects of SARS-CoV-2 Spike Mutation D614G on Transmissibility and Pathogenicity","volume":"184","author":"E Volz","year":"2021","journal-title":"Cell"},{"key":"pone.0262316.ref089","doi-asserted-by":"crossref","unstructured":"Tegally H, Wilkinson E, Giovanetti M, Iranzadeh A, Fonseca V, Giandhari J, et al. Emergence and rapid spread of a new severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) lineage with multiple spike mutations in South Africa. medRxiv. 2020; p. 2020.12.21.20248640.","DOI":"10.1101\/2020.12.21.20248640"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0262316","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,14]],"date-time":"2022-01-14T19:34:26Z","timestamp":1642188866000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0262316"}},"subtitle":[],"editor":[{"given":"Amitava","family":"Mukherjee","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2022,1,14]]},"references-count":89,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2022,1,14]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0262316","relation":{},"ISSN":["1932-6203"],"issn-type":[{"type":"electronic","value":"1932-6203"}],"subject":[],"published":{"date-parts":[[2022,1,14]]}}}