{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T18:24:42Z","timestamp":1793816682899,"version":"4.6.1"},"reference-count":53,"publisher":"Public Library of Science (PLoS)","issue":"2","license":[{"start":{"date-parts":[[2022,2,7]],"date-time":"2022-02-07T00:00:00Z","timestamp":1644192000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100010663","name":"H2020 European Research Council","doi-asserted-by":"publisher","award":["Marie Skoldowska-Curie grant agreement No 713606"],"award-info":[{"award-number":["Marie Skoldowska-Curie grant agreement No 713606"]}],"id":[{"id":"10.13039\/100010663","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\">\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>The incidence of acetabular fractures due to low-energy falls is increasing among the geriatric population. Studies have shown that several biomechanical factors such as body configuration, impact velocity, and trochanteric soft-tissue thickness contribute to the severity and type of acetabular fracture. The effect of reduction in apparent density and elastic modulus of bone as well as other bone mechanical properties due to osteoporosis on low-energy acetabular fractures has not been investigated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec002\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The current comprehensive finite element study aimed to study the effect of reduction in bone mechanical properties (trabecular, cortical, and trabecular + cortical) on the risk and type of acetabular fracture. Also, the effect of reduction in the mechanical properties of bone on the load-transferring mechanism within the pelvic girdle was examined.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec003\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We observed that while the reduction in the mechanical properties of trabecular bone considerably affects the severity and area of trabecular bone failure, reduction in mechanical properties of cortical bone moderately influences both cortical and trabecular bone failure. The results also indicated that by reducing bone mechanical properties, the type of acetabular fracture turns from elementary to associated, which requires a more extensive intervention and rehabilitation period. Finally, we observed that the cortical bone plays a substantial role in load transfer, and by increasing reduction in the mechanical properties of cortical bone, a greater share of load is transmitted toward the pubic symphysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec004\">\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This study increases our understanding of the effect of osteoporosis progression on the incidence of low-energy acetabular fractures. The osteoporosis-related reduction in the mechanical properties of cortical bone appears to affect both the cortical and trabecular bones. Also, during the extreme reduction in the mechanical properties of bone, the acetabular fracture type will be more complicated. Finally, during the final stages of osteoporosis (high reduction in mechanical properties of bone) a smaller share of impact load is transferred by impact-side hemipelvis to the sacrum, therefore, an osteoporotic pelvis might mitigate the risk of sacral fracture.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1371\/journal.pone.0263458","type":"journal-article","created":{"date-parts":[[2022,2,7]],"date-time":"2022-02-07T13:26:52Z","timestamp":1644240412000},"page":"e0263458","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":13,"title":["Effect of osteoporosis-related reduction in the mechanical properties of bone on the acetabular fracture during a sideways fall: A parametric finite element approach"],"prefix":"10.1371","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1795-4404","authenticated-orcid":true,"given":"Shahab","family":"Khakpour","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amir","family":"Esrafilian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9684-6902","authenticated-orcid":true,"given":"Petri","family":"Tanska","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mika E.","family":"Mononen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rami K.","family":"Korhonen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timo","family":"J\u00e4ms\u00e4","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2022,2,7]]},"reference":[{"issue":"2 A","key":"pone.0263458.ref001","article-title":"The crippling consequences of fractures and their impact on quality of life","volume":"103","author":"C Cooper","year":"1997","journal-title":"Am J Med"},{"issue":"6","key":"pone.0263458.ref002","doi-asserted-by":"crossref","first-page":"298","DOI":"10.5694\/j.1326-5377.2004.tb05931.x","article-title":"7: Treatment of osteoporosis: Why, whom, when and how to treat","volume":"180","author":"E Seeman","year":"2004","journal-title":"Med J Aust"},{"issue":"SUPPL. 7","key":"pone.0263458.ref003","first-page":"181","article-title":"Importance of early diagnosis and treatment of osteoporosis to prevent fractures","volume":"12","author":"JR Tucci","year":"2006","journal-title":"Am J Manag Care"},{"key":"pone.0263458.ref004","author":"DW Dempster","year":"2014","journal-title":"Osteoporosis and the Burden of Osteoporosis-Related Fractures"},{"issue":"6","key":"pone.0263458.ref005","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1007\/s00223-015-0056-8","article-title":"Low-Trauma Pelvic Fractures in Elderly Finns in 1970\u20132013","volume":"97","author":"P Kannus","year":"2015","journal-title":"Calcif Tissue Int"},{"issue":"March","key":"pone.0263458.ref006","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1016\/j.bone.2019.07.004","article-title":"Structural risk factors for low-energy acetabular fractures","volume":"127","author":"RK Gebre","year":"2019","journal-title":"Bone"},{"issue":"2","key":"pone.0263458.ref007","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1302\/0301-620X.92B2.22488","article-title":"Fractures of the acetabulum in patients aged 60 years and older: An epidemiological and radiological study","volume":"92","author":"TA Ferguson","year":"2010","journal-title":"J Bone Jt Surg\u2014Ser B"},{"issue":"6","key":"pone.0263458.ref008","doi-asserted-by":"crossref","first-page":"1410","DOI":"10.1016\/j.injury.2021.03.013","article-title":"Increasing incidence of pelvic and acetabular fractures. 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