{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,26]],"date-time":"2025-12-26T07:08:20Z","timestamp":1766732900715,"version":"3.37.3"},"reference-count":37,"publisher":"Public Library of Science (PLoS)","issue":"2","license":[{"start":{"date-parts":[[2022,2,17]],"date-time":"2022-02-17T00:00:00Z","timestamp":1645056000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Grants-in-Aid for Scientific Research (KAKENHI) Research C","award":["20k09439"],"award-info":[{"award-number":["20k09439"]}]},{"name":"Japanese Orthopaedics and Traumatology Foundation, Inc","award":["287"],"award-info":[{"award-number":["287"]}]},{"name":"H-25-Choujyu-007"},{"name":"H25-Nanchitou (Men)-005"},{"DOI":"10.13039\/501100003478","name":"Ministry of Health, Labour and Welfare","doi-asserted-by":"publisher","award":["201417014A"],"award-info":[{"award-number":["201417014A"]}],"id":[{"id":"10.13039\/501100003478","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Grant-in-Aid for Scientific Research","award":["C 26861206"],"award-info":[{"award-number":["C 26861206"]}]},{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology in Japan","doi-asserted-by":"crossref","award":["NSF 08033011\u201300262"],"award-info":[{"award-number":["NSF 08033011\u201300262"]}],"id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Japan Osteoporosis Society"},{"DOI":"10.13039\/100004427","name":"Center for Global Partnership","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004427","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Japan Osteoporosis Society"},{"DOI":"10.13039\/100018590","name":"JA Kyosai Research Institute","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100018590","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Grants-in-Aid for Scientific Research (KAKENHI) Research C","award":["17K10937"],"award-info":[{"award-number":["17K10937"]}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\">\n<jats:title>Objectives<\/jats:title>\n<jats:p>This prospective study aimed to determine the association between radiographic lumbar spinal stenosis (LSS) and the quality of life (QOL) in the general Japanese population.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec002\">\n<jats:title>Methods<\/jats:title>\n<jats:p>The severity of radiographic LSS was qualitatively graded on axial magnetic resonance images as follows: no stenosis, mild stenosis with \u22641\/3 narrowing, moderate stenosis with a narrowing between 1\/3 and 2\/3, and severe stenosis with &gt; 2\/3 narrowing. Patients less than 40 years of age and those who had undergone previous lumbar spine surgery were excluded from the study. The Oswestry Disability Index (ODI), which includes 10 sections, was used to assess the QOL. One-way analysis of variance was performed to determine the statistical relationship between radiographic LSS and ODI. Further, logistic regression analysis adjusted for gender, age, and body mass index was performed to detect the relationship.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec003\">\n<jats:title>Results<\/jats:title>\n<jats:p>Complete data were available for 907 patients (300 men and 607 women; mean age, 67.3\u00b112.4 years). The prevalence of severe, moderate, and non-mild\/non-radiographic were 30%, 48%, and 22%, respectively. In addition, the mean values of ODI in each group were 12.9%, 13.1%, and 11.7%, respectively, and there was no statistically significant difference between the three groups in logistic analysis (P = 0.55). In addition, no significant differences in any section of the ODI were observed among the groups. However, severe radiographic LSS was associated with low back pain in the \"severe\" group as determined by logistic analysis adjusted for gender, age, and body mass index (odds ratio: 1.53, confidence interval: 1.13\u20132.07) compared with the non-severe group.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec004\">\n<jats:title>Conclusion<\/jats:title>\n<jats:p>In this general population study, severe radiographic LSS was associated with low back pain (LBP), but did not affect ODI.<\/jats:p>\n<\/jats:sec>","DOI":"10.1371\/journal.pone.0263930","type":"journal-article","created":{"date-parts":[[2022,2,17]],"date-time":"2022-02-17T18:39:36Z","timestamp":1645123176000},"page":"e0263930","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":6,"title":["Is radiographic lumbar spinal stenosis associated with the quality of life?: The Wakayama Spine Study"],"prefix":"10.1371","volume":"17","author":[{"given":"Satoshi","family":"Arita","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuyu","family":"Ishimoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Hashizume","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keiji","family":"Nagata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shigeyuki","family":"Muraki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroyuki","family":"Oka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masanari","family":"Takami","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shunji","family":"Tsutsui","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Iwasaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasutsugu","family":"Yukawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toru","family":"Akune","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Kawaguchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sakae","family":"Tanaka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kozo","family":"Nakamura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Munehito","family":"Yoshida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noriko","family":"Yoshimura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Yamada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Consortium","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2022,2,17]]},"reference":[{"key":"pone.0263930.ref001","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1016\/j.spinee.2010.10.019","article-title":"Walking assessment in people with lumbar spinal stenosis: capacity, performance, and self-report measures","volume":"11","author":"J Conway","year":"2011","journal-title":"Spine J"},{"key":"pone.0263930.ref002","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1186\/1471-2474-11-233","article-title":"Walking ability during daily life in patients with osteoarthritis of the knee or the hip and lumbar spinal stenosis: a cross sectional study","volume":"11","author":"CC Winter","year":"2010","journal-title":"BMC Musculoskelet Disord"},{"key":"pone.0263930.ref003","doi-asserted-by":"crossref","first-page":"1855","DOI":"10.1007\/s00586-010-1324-y","article-title":"Step activity monitoring in lumbar stenosis patients undergoing decompressive surgery","volume":"19","author":"TL Schulte","year":"2010","journal-title":"Eur Spine J"},{"key":"pone.0263930.ref004","doi-asserted-by":"crossref","first-page":"1178","DOI":"10.1097\/00007632-199505150-00013","article-title":"Lumbar spinal stenosis. 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