{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T17:12:27Z","timestamp":1788541947968,"version":"build-2803163510"},"reference-count":34,"publisher":"Public Library of Science (PLoS)","issue":"3","license":[{"start":{"date-parts":[[2022,3,4]],"date-time":"2022-03-04T00:00:00Z","timestamp":1646352000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\">\n<jats:title>Introduction<\/jats:title>\n<jats:p>Birth asphyxia is a prominent and avoidable cause of infant illness and death worldwide, particularly in underdeveloped countries such as Ethiopia. Early identification and control of the underlying contributory factors would help to alleviate the situation. As a result, the goal of this study was to assess the magnitude and determinants of neonatal asphyxia among live newborns at the northern Gondar public Hospitals in northwest Ethiopia.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec002\">\n<jats:title>Materials and methods<\/jats:title>\n<jats:p>From April 1 to May 2, 2020, 357 newborns were studied in an institution-based cross-sectional study. The sample size was proportionally distributed among three public hospitals, namely Gondar referral teaching hospital, Debark general hospital, and Kola-Diba District Hospital, which was chosen at random. The number of deliveries given at each hospital six months prior to the data collecting period was used to allocate the hospitals. To get all participants, a systematic random sampling approach was adopted based on hospital delivery registration. The physicians\u2019 evaluation of an APGAR score of 7 in the first and fifth minutes of birth was used as the confirmation of birth asphyxia. Data was collected using a standardized and pretested questionnaire. Variables having p-values less than 0.25 were entered into a multivariable logistic regression analysis in the bivariable analysis. At a p-value of 0.05, a statistically significant level was reported.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec003\">\n<jats:title>Results<\/jats:title>\n<jats:p>As per the study, the total prevalence of neonatal asphyxia was found to be 27.1 (95% CI: 21.4, 32.7). In a multivariable logistic regression analysis, neonates born to rural mothers (AOR = 2.441, 95% CI: 1.137, 5.241), primiparity (AOR = 5.521 95%CI: 1.691, 8.026), premature rupture of membrane, (AOR = 3.202, 95% CI: 1.484, 6.909) and low birth weight (&lt; 2.5kg) (AOR = 3.706, 95%CI: 3.307, 4.152) were all found to be independent predictors of birth asphyxia.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec004\">\n<jats:title>Conclusion<\/jats:title>\n<jats:p>This study identified that rural residence, primiparity, premature rupture of membrane, and birth weight were found to be the independent predictors of birth asphyxia. The majority of variables that cause birth asphyxia can be controlled.<\/jats:p>\n<\/jats:sec>","DOI":"10.1371\/journal.pone.0264816","type":"journal-article","created":{"date-parts":[[2022,3,4]],"date-time":"2022-03-04T18:25:12Z","timestamp":1646418312000},"page":"e0264816","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":19,"title":["The magnitude of neonatal asphyxia and its associated factors among newborns in public hospitals of North Gondar Zone, Northwest Ethiopia: A cross-sectional study"],"prefix":"10.1371","volume":"17","author":[{"given":"Fitalew Tadele","family":"Admasu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Biruk Demssie","family":"Melese","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tadeg Jemere","family":"Amare","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edget Abebe","family":"Zewude","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chalachew Yenew","family":"Denku","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2033-6113","authenticated-orcid":true,"given":"Tadesse Asmamaw","family":"Dejenie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2022,3,4]]},"reference":[{"key":"pone.0264816.ref001","unstructured":"Organization WH. Newborn death and illness. 2015."},{"key":"pone.0264816.ref002","unstructured":"Organization WH. Guidelines on Basic Newborn Resuscitation. World Heal Organ. 2012."},{"key":"pone.0264816.ref003","unstructured":"Fund UNCs. Level and Trends in Child Mortality. 2017."},{"key":"pone.0264816.ref004","unstructured":"Lincetto O. Birth Asphyxia\u2014Summary of the Previous Meeting and Protocol Overview. 2007."},{"key":"pone.0264816.ref005","unstructured":"UNICEF. Committing to Child Survival: A Promise. 2015."},{"key":"pone.0264816.ref006","article-title":"Maternal and Newborn Health\/Safe Motherhood Unit. Division of Reproductive Health (Technical Support)","volume":"4","author":"Organization WH","year":"1997","journal-title":"Basic Newborn Resuscitation: A Practical Guide"},{"key":"pone.0264816.ref007","unstructured":"Shaun Odell M. Global Burden Of Neonatal Disease: Caring For The World\u2019s Most Vulnerable Patients, newborn pediatric critical care conference. 2017."},{"key":"pone.0264816.ref008","unstructured":"Organization WH. Maternal and Child Epidemiology Estimation Group (MCEE). Estimates for child causes of death 2000\u20132016. 2018."},{"key":"pone.0264816.ref009","article-title":"Risk Factors for Neonatal Mortality Due to Birth Asphyxia in Southern Nepal: A Prospective, Community-Based Cohort Study","author":"AC Lee","year":"2008","journal-title":"American Academy of Pediatrics"},{"key":"pone.0264816.ref010","article-title":"Risk Factors Associated with Birth Asphyxia in Rural District Matiari, Pakistan: A Case-Control Study","volume":"21","author":"F Tabassum","year":"2014","journal-title":"International Journal of Clinical Medicine"},{"key":"pone.0264816.ref011","author":"DT Hibstu","year":"2013","journal-title":"Determinants of Neonatal Mortality in Ethiopia: A Case-Control Study"},{"key":"pone.0264816.ref012","author":"L Wosenu","year":"2018","journal-title":"Determinants of birth asphyxia among live birth newborns in University of Gondar referral hospital, northwest Ethiopia: A case-control study"},{"key":"pone.0264816.ref013","author":"MI Herrera","year":"2017","journal-title":"Could Perinatal Asphyxia Induce a Synaptopathy? New Highlights from an Experimental Model"},{"key":"pone.0264816.ref014","author":"J Lawn","year":"2005","journal-title":"4 million neonatal deaths: when? Where? Why?"},{"key":"pone.0264816.ref015","author":"J Lawn","year":"2009","journal-title":"Two million intrapartum-related stillbirths and neonatal deaths: where, why, and what can be done?"},{"key":"pone.0264816.ref016","author":"H Uzel","year":"2012","journal-title":"Neonatal Asphyxia a Study Of 210 Cases J Clinical Experiment"},{"key":"pone.0264816.ref017","doi-asserted-by":"crossref","unstructured":"American Academy of Pediatrics CoFaNACoOaGaCoOP. The Apgar score. 2006 117.","DOI":"10.1542\/peds.2006-0325"},{"key":"pone.0264816.ref018","article-title":"Birth asphyxia and associated factors among newborns delivered in Jimma zone public hospitals, Southwest Ethiopia: A cross-sectional study","author":"Z Wayessa","year":"2018","journal-title":"Journal of Midwifery and Reproductive Health"},{"key":"pone.0264816.ref019","author":"A Alemu","year":"2017","journal-title":"Prevalence and associated factors of perinatal asphyxia among newborns in Dilla University referral hospital, Southern Ethiopia Pediatric Health, Medicine and Therapeutics"},{"key":"pone.0264816.ref020","unstructured":"WHO. Global health observatory data repository world health organization. 2015."},{"key":"pone.0264816.ref021","article-title":"Perinatal risk factors for neonatal asphyxia in Vali-e-Asr hospital, Tehran-Iran","author":"F Nayeri","year":"2012","journal-title":"Iran J Reprod Med"},{"key":"pone.0264816.ref022","article-title":"perinatal mortality and associated risk factors: a case-control study","author":"Getachew","year":"2012","journal-title":"Ethiopia Journal of Health Science"},{"key":"pone.0264816.ref023","article-title":"Risk Factors for Birth Asphyxia Mortality in a Community-Based Setting in Southern Nepal","author":"A Lee","year":"2007","journal-title":"MPH Baltimore: Capstone Johns Hopkins School of Public Health"},{"key":"pone.0264816.ref024","author":"K Zenebe","year":"2014","journal-title":"Low birth weight and associated factors among newborns in Gondar Town, North West Ethiopia: Institutional based cross-sectional study"},{"key":"pone.0264816.ref025","author":"A Eshete","year":"2013","journal-title":"Birth outcomes among laboring mothers in selected health facilities of North Wollo Zone, Northeast Ethiopia: A facility-based cross-sectional study"},{"key":"pone.0264816.ref026","unstructured":"Roba A, Diro D. Morbidities, Rate and Time Trends of Neonatal Mortality in Dilchora Referral Hospital, Dire Dawa, Ethiopia. 2019."},{"key":"pone.0264816.ref027","author":"C Onyearugha","year":"2010","journal-title":"Severe birth asphyxia: risk factors as seen in a tertiary institution in the niger delta area of Nigeria"},{"key":"pone.0264816.ref028","author":"B Gane","year":"2013","journal-title":"Antenatal and intrapartum risk factors for perinatal asphyxia: a case-control study"},{"key":"pone.0264816.ref029","article-title":"Maternal associated factors of low birth weight: A hospital-based cross-sectional mixed study in Tigray, Northern Ethiopia","author":"M Gebremedhin","year":"2015","journal-title":"Maternal associated factors of low birth weight: A hospital-based cross-sectional mixed study in Tigray, Northern Ethiopia"},{"key":"pone.0264816.ref030","unstructured":"Jagkaew B. Factors associated with birth asphyxia in Fang Hospital. Mahasarakham Hospital. 2014."},{"key":"pone.0264816.ref031","article-title":"Risk factors for birth asphyxia in an urban health facility in Cameroon","author":"A Chiabi","year":"2013","journal-title":"Iran J Child Neurol"},{"key":"pone.0264816.ref032","article-title":"Antenatal and intrapartum risk factors for birth asphyxia among emergency obstetric referrals in Mulago Hospital, Kampala, Uganda","author":"D Kaye","year":"2003","journal-title":"East Afr Med J"},{"key":"pone.0264816.ref033","article-title":"Risk factors of perinatal asphyxia: a study at Al-Diwaniya maternity and children teaching hospital","author":"H. Sahib","year":"2015","journal-title":"Risk"},{"key":"pone.0264816.ref034","author":"A Chiabi","year":"2013","journal-title":"Risk Factors for Birth Asphyxia in an Urban Health Facility in Cameroon"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0264816","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,4]],"date-time":"2022-03-04T18:25:33Z","timestamp":1646418333000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0264816"}},"subtitle":[],"editor":[{"given":"Francesca","family":"Crovetto","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2022,3,4]]},"references-count":34,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2022,3,4]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0264816","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,3,4]]}}}