{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T17:22:15Z","timestamp":1778865735567,"version":"3.51.4"},"reference-count":27,"publisher":"Public Library of Science (PLoS)","issue":"3","license":[{"start":{"date-parts":[[2022,3,17]],"date-time":"2022-03-17T00:00:00Z","timestamp":1647475200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Pr\u00f3-Reitoria de Pesquisa e Inovac\u00e3o da Universidade Federal de Pernambuco","award":["23076.019663\/2020-47"],"award-info":[{"award-number":["23076.019663\/2020-47"]}]},{"name":"Pr\u00f3-Reitoria de Pesquisa e Inovac\u00e3o da Universidade Federal de Pernambuco","award":["23076.019632\/2020-11"],"award-info":[{"award-number":["23076.019632\/2020-11"]}]},{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","award":["001"],"award-info":[{"award-number":["001"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["305696\/2018-1"],"award-info":[{"award-number":["305696\/2018-1"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["309617\/2019-7"],"award-info":[{"award-number":["309617\/2019-7"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:p>Serological databases represent an important source of information to perceive COVID-19 impact on health professionals involved in combating the disease. This paper describes<jats:italic>SerumCovid<\/jats:italic>, a COVID-19 serological database focused on the diagnosis of health professionals, providing a preliminary analysis to contribute to the understanding of the antibody response to the SARS-CoV-2. The study population comprises 321 samples from 236 healthcare and frontline workers fighting COVID-19 in Vit\u00f3ria de Santo Ant\u00e3o, Brazil. Samples were collected from at least six days of symptoms to more than 100 days. The used immunoenzymatic assays were Euroimmun Anti-SARS-CoV-2 ELISA IgG and IgA. The most common gender in<jats:italic>SerumCovid<\/jats:italic>is female, while the most common age group is between 30 and 39 years old. However, no statistical differences were observed in either genders or age categories. The most reported symptoms were fatigue, headaches, and myalgia. Still, some subjects presented positive results for IgA after 130 days. Based on a temporal analysis, we have not identified general patterns as subjects presented high and low values of IgA and IgG with different evolution trends. Unexpectedly, for subjects with both serological tests, the outcome of IgA and IgG tests were the same (either positive or negative) for more than 80% of the samples. Therefore,<jats:italic>SerumCovid<\/jats:italic>helps better understand how COVID-19 affected healthcare and frontline workers, which increases knowledge about the infection and enables direct prevention actions.<\/jats:p>","DOI":"10.1371\/journal.pone.0265016","type":"journal-article","created":{"date-parts":[[2022,3,17]],"date-time":"2022-03-17T18:20:37Z","timestamp":1647541237000},"page":"e0265016","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":3,"title":["SerumCovid database: Description and preliminary analysis of serological COVID-19 diagnosis in healthcare workers"],"prefix":"10.1371","volume":"17","author":[{"given":"Isis Didier","family":"Lins","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leonardo 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