{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T02:07:10Z","timestamp":1783130830274,"version":"3.54.6"},"reference-count":36,"publisher":"Public Library of Science (PLoS)","issue":"4","license":[{"start":{"date-parts":[[2022,4,4]],"date-time":"2022-04-04T00:00:00Z","timestamp":1649030400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"\nBackground<\/jats:title>\nAnemia is a condition in which the number of red blood cells is inadequate to meet the physiologic needs of the human body oxygen and it is highly prevalent among individuals with metabolic syndromes as a complication in turn speed up the progression and the number of adverse outcomes unless the proper measure is undertaken. Determination of anemia may play a major role in the management and early aversion of complications in an admitted patient with metabolic syndromes. Therefore, this study aimed to determine anemia and its associated factors among patients with admitted metabolic syndromes at Worabe Comprehensive Specialized hospital, Southern Ethiopia from March 1 to May 30, 2021.<\/jats:p>\n<\/jats:sec>\n\nMethods and materials<\/jats:title>\nAn institutional-based cross-sectional study design was conducted on 324 adult patients admitted with metabolic syndromes. Structured questionnaires through face-to-face interviews and participants\u2019 medical records were used to collect information on determinants related to anemia. A blood sample was collected to determine hematological parameters, biochemical profile, and blood film preparation. Data were analyzed by SPSS version 22. Binary logistic regression analyses were done to identify factors associated with anemia. The p-value was set at <0.05 with a 95% confidence interval of the adjusted odds ratio.<\/jats:p>\n<\/jats:sec>\n\nResults<\/jats:title>\nA total of 324 admitted adult patients with metabolic syndromes were involved. The overall prevalence of anemia among study participants was 25.3% (95%CI: 20.7, 30.2), of which 52.4% had moderate anemia and 56% had microcytic types of anemia. Being alcoholic (AOR = 6.25, 95% CI: (3.05, 12.82)), obese (AOR = 3.34, 95% CI: (1.02, 11.21)), dyslipidemic (AOR = 2.06, 95% CI: (1.02, 4.17)), and diabetic (AOR = 2.61, 95%CI: (1.31, 5.21)) were significantly associated with anemia.<\/jats:p>\n<\/jats:sec>\n\nConclusion<\/jats:title>\nThe prevalence of anemia among patients admitted with metabolic syndrome observed in this study was a moderate public health problem. Taking alcohol, being dyslipidemic, obese and diabetic was significantly associated with anemia. The finding of this study should be taken into consideration to implement preventive interventions on identified factors in study percipients. Taking fruit and vegetable, and promoting physical exercise, routine determination of fasting blood glucose and hemoglobin level in adult admitted metabolic syndromes patients were recommended to minimize the emergence of anemia.<\/jats:p>\n<\/jats:sec>","DOI":"10.1371\/journal.pone.0266089","type":"journal-article","created":{"date-parts":[[2022,4,4]],"date-time":"2022-04-04T17:25:31Z","timestamp":1649093131000},"page":"e0266089","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":13,"title":["Anemia and associated factors among patients admitted with metabolic syndromes at Worabe Comprehensive Specialized Hospital, Southern Ethiopia: A cross-sectional study"],"prefix":"10.1371","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2606-2918","authenticated-orcid":true,"given":"Abebe","family":"Timerga","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2520-9244","authenticated-orcid":true,"given":"Kassahun","family":"Haile","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9800-1076","authenticated-orcid":true,"given":"Samuel","family":"Dessu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2022,4,4]]},"reference":[{"issue":"3","key":"pone.0266089.ref001","doi-asserted-by":"crossref","first-page":"167","DOI":"10.7326\/0003-4819-140-3-200402030-00007","article-title":"The Metabolic Syndrome and Chronic Kidney Disease in U.S. Adults","volume":"140","year":"2004","journal-title":"Ann Intern Med"},{"issue":"6","key":"pone.0266089.ref002","doi-asserted-by":"crossref","DOI":"10.22159\/ajpcr.2018.v11i6.24658","article-title":"Metabolic syndromes\u2014an emerging risk factor for chronic kidney disease","volume":"11","author":"A Shenai","year":"2018","journal-title":"Asian J Pharm Clin Res"},{"issue":"76","key":"pone.0266089.ref003","first-page":"1","article-title":"Hyperuricemia and metabolic syndrome in type 2 diabetes mellitus patients at Hawassa university comprehensive specialized hospital, South West Ethiopia","volume":"17","author":"SB Woyesa","year":"2017","journal-title":"BMC Endocr Disord"},{"issue":"3","key":"pone.0266089.ref004","first-page":"1223","article-title":"Prevalence of Anemia Types Among Overweight and Obese Patients Attending The Obesity Research and Therapy Unit at AL-Kindy College of Medicine","volume":"24","author":"Z Al-attar","year":"2020","journal-title":"J Immunol"},{"issue":"12","key":"pone.0266089.ref005","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.pone.0225725","article-title":"Anemia and associated factors among type-2 diabetes mellitus patients attending public hospitals in Harari Region, Eastern Ethiopia","volume":"14","author":"A Bekele","year":"2019","journal-title":"PLoS One"},{"issue":"11","key":"pone.0266089.ref006","first-page":"1","article-title":"Prevalence of Anemia, Overweight \/ Obesity, and Undiagnosed Hypertension and Diabetes among Residents of Selected Communities in Ghana","volume":"17","author":"AK Anderson","year":"2017","journal-title":"Hindawi"},{"issue":"10","key":"pone.0266089.ref007","first-page":"1","article-title":"Association of Body Mass Index with Hemoglobin Concentration and Iron Parameters in Iranian Population","volume":"14","author":"A Ghadiri-anari","year":"2014","journal-title":"Hindawi"},{"issue":"2","key":"pone.0266089.ref008","doi-asserted-by":"crossref","first-page":"57","DOI":"10.14740\/jh411w","article-title":"Prevalence of Anemia in Type 2 Diabetic Patients","volume":"7","author":"SM Aldallal","year":"2018","journal-title":"J Hematol"},{"issue":"21","key":"pone.0266089.ref009","article-title":"Obesity and iron deficiency: A quantitative meta-analysis","volume":"15","author":"L Zhao","year":"2015","journal-title":"World Obes"},{"issue":"10","key":"pone.0266089.ref010","doi-asserted-by":"crossref","first-page":"2356","DOI":"10.1038\/oby.2008.353","article-title":"Is Obesity Associated With Anemia of Chronic Disease? 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