{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T22:11:48Z","timestamp":1771539108817,"version":"3.50.1"},"reference-count":31,"publisher":"Public Library of Science (PLoS)","issue":"4","license":[{"start":{"date-parts":[[2022,4,13]],"date-time":"2022-04-13T00:00:00Z","timestamp":1649808000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Charley's Fund"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\"><jats:title>Background<\/jats:title><jats:p>Patients with Duchenne muscular dystrophy (DMD) adopt compensatory movement patterns as muscles weaken. The Duchenne Video Assessment (DVA) measures patient ease of movement through identification of compensatory movement patterns. The DVA directs caregivers to video record patients performing specific movement tasks at home using a secure mobile application, and DVA-certified physical therapists (PTs) score the videos using scorecards with prespecified compensatory movement criteria. The goal of this study was to develop and refine the DVA scorecards.<\/jats:p><\/jats:sec><jats:sec id=\"sec002\"><jats:title>Methods<\/jats:title><jats:p>To develop the initial scorecards, 4 PTs collaboratively created compensatory movement lists for each task, and researchers structured the lists into scorecards. A 2-round modified Delphi process was used to gather expert opinion on the understandability, comprehensiveness, and clinical meaningfulness of the compensatory movements on the scorecards. Eight PTs who had evaluated \u226550 patients with DMD and participated in \u226510 DMD clinical trials were recruited for the panel. In Round 1, panelists evaluated compensatory movement criteria understandability via questionnaire and tested the scorecards. In Round 2, panelists participated in an in-person meeting to discuss areas of disagreement from Round 1 and reach consensus (\u226575% agreement) on all revisions to the scorecards.<\/jats:p><\/jats:sec><jats:sec id=\"sec003\"><jats:title>Results<\/jats:title><jats:p>During the Round 1 revisions to the scorecards, there were 67 changes (44%) to the wording of 153 original compensatory movement criteria and 3 criteria were removed. During the Round 2 revisions to the scorecards, there were 47 changes (31%) to the wording of 150 compensatory movement criteria, 20 criteria were added, and 30 criteria were removed. The panel reached 100% agreement on all changes made to scorecards during Round 2.<\/jats:p><\/jats:sec><jats:sec id=\"sec004\"><jats:title>Conclusion<\/jats:title><jats:p>PTs with extensive experience evaluating patients with DMD confirmed that the compensatory movement criteria included in the DVA scorecards were understandable, comprehensive, and clinically meaningful.<\/jats:p><\/jats:sec>","DOI":"10.1371\/journal.pone.0266845","type":"journal-article","created":{"date-parts":[[2022,4,13]],"date-time":"2022-04-13T17:46:18Z","timestamp":1649871978000},"page":"e0266845","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":11,"title":["Development of Duchenne Video Assessment scorecards to evaluate ease of movement among those with Duchenne muscular dystrophy"],"prefix":"10.1371","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4769-1617","authenticated-orcid":true,"given":"Marielle G.","family":"Contesse","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4206-0557","authenticated-orcid":true,"given":"Linda P.","family":"Lowes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michelle K.","family":"White","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Dalle Pazze","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christine","family":"McSherry","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lindsay N.","family":"Alfano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2800-3855","authenticated-orcid":true,"given":"Megan","family":"Iammarino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natalie","family":"Reash","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kelly","family":"Bonarrigo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0891-2592","authenticated-orcid":true,"given":"Michael","family":"Kiefer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katie","family":"Laubscher","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melissa","family":"McIntyre","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shelley","family":"Mockler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3606-5757","authenticated-orcid":true,"given":"Leslie","family":"Nelson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leslie","family":"Vogel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mindy G.","family":"Leffler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2022,4,13]]},"reference":[{"key":"pone.0266845.ref001","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1186\/s13023-017-0631-3","article-title":"The burden, epidemiology, costs and treatment for Duchenne muscular dystrophy: an evidence review","volume":"12","author":"S Ryder","year":"2017","journal-title":"Orphanet Journal of Rare Diseases"},{"key":"pone.0266845.ref002","volume-title":"Duchenne Muscular Dystrophy and Related Dystrophinopathies: Developing Drugs for Treatment.","author":"U.S. Food & Drug Administration","year":"2018"},{"key":"pone.0266845.ref003","doi-asserted-by":"crossref","first-page":"90","DOI":"10.33590\/emj\/10311993","article-title":"State-Of-The-Art Advances in Duchenne Muscular Dystrophy.","volume":"2","author":"H Van Ruiten","year":"2017","journal-title":"EMJ"},{"key":"pone.0266845.ref004","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/S1474-4422(18)30025-5","article-title":"Diagnosis and management of Duchenne muscular dystrophy, part 2: respiratory, cardiac, bone health, and orthopaedic management.","volume":"17","author":"DJ Birnkrant","year":"2018","journal-title":"Lancet Neurol."},{"key":"pone.0266845.ref005","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1111\/dmcn.14129","article-title":"A new era in the management of Duchenne muscular dystrophy.","volume":"61","author":"R. Korinthenberg","year":"2019","journal-title":"Developmental Medicine & Child Neurology."},{"key":"pone.0266845.ref006","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1002\/phar.1909","article-title":"Advances in the Treatment of Duchenne Muscular Dystrophy: New and Emerging Pharmacotherapies.","volume":"37","author":"AM Reinig","year":"2017","journal-title":"Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy."},{"key":"pone.0266845.ref007","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41572-021-00248-3","article-title":"Duchenne muscular dystrophy","volume":"7","author":"D Duan","year":"2021","journal-title":"Nature Reviews Disease Primers"},{"key":"pone.0266845.ref008","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1177\/0031512521998278","article-title":"Motor Compensation Strategies for Reduced Upper Limb Function Among Individuals With Duchenne Muscular Dystrophy.","volume":"128","author":"L Maciel FK de","year":"2021","journal-title":"Percept Mot Skills."},{"key":"pone.0266845.ref009","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1186\/s12984-019-0515-y","article-title":"Don\u2019t forget the trunk in Duchenne muscular dystrophy patients: more muscle weakness and compensation than expected","volume":"16","author":"LHC Peeters","year":"2019","journal-title":"Journal of NeuroEngineering and Rehabilitation"},{"key":"pone.0266845.ref010","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.gaitpost.2008.06.002","article-title":"Gait pattern in Duchenne muscular dystrophy.","volume":"29","author":"MG D\u2019Angelo","year":"2009","journal-title":"Gait & Posture."},{"key":"pone.0266845.ref011","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.clnu.2017.02.004","article-title":"Why Intensity is not a Bad Word: Optimizing Health Status at any Age.","volume":"37","author":"GR Hunter","year":"2018","journal-title":"Clin Nutr."},{"key":"pone.0266845.ref012","doi-asserted-by":"crossref","first-page":"329","DOI":"10.2165\/00007256-200434050-00005","article-title":"Effects of resistance training on older adults.","volume":"34","author":"GR Hunter","year":"2004","journal-title":"Sports Med."},{"key":"pone.0266845.ref013","doi-asserted-by":"crossref","first-page":"B443","DOI":"10.1093\/gerona\/56.10.B443","article-title":"The interrelationship among muscle mass, strength, and the ability to perform physical tasks of daily living in younger and older women","volume":"56","author":"KA Landers","year":"2001","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"pone.0266845.ref014","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1002\/pri.520","article-title":"Development of a functional assessment scale for ambulatory boys with Duchenne muscular dystrophy","volume":"17","author":"E Scott","year":"2012","journal-title":"Physiother Res Int"},{"key":"pone.0266845.ref015","doi-asserted-by":"crossref","first-page":"e0199223","DOI":"10.1371\/journal.pone.0199223","article-title":"Upper limb function in Duchenne muscular dystrophy: 24 month longitudinal data.","volume":"13","author":"M Pane","year":"2018","journal-title":"PLoS One."},{"key":"pone.0266845.ref016","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1186\/s12955-021-01813-w","article-title":"Development of a Clinical Global Impression of Change (CGI-C) and a Caregiver Global Impression of Change (CaGI-C) measure for ambulant individuals with Duchenne muscular dystrophy.","volume":"19","author":"H Staunton","year":"2021","journal-title":"Health and Quality of Life Outcomes."},{"key":"pone.0266845.ref017","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1002\/mus.21544","article-title":"The 6-minute walk test as a new outcome measure in Duchenne muscular dystrophy","volume":"41","author":"CM McDonald","year":"2010","journal-title":"Muscle Nerve"},{"key":"pone.0266845.ref018","doi-asserted-by":"crossref","first-page":"2979","DOI":"10.1007\/s11136-019-02245-2","article-title":"Adapting traditional content validation methods to fit purpose: an example with a novel video assessment and training materials in Duchenne muscular dystrophy (DMD).","volume":"28","author":"MK White","year":"2019","journal-title":"Qual Life Res"},{"key":"pone.0266845.ref019","unstructured":"Leffler MG, Contesse MG, Staunton H. Home-Based Video Assessment of the Quality of Movement of Patients with Duchenne: Interviews with Physical Therapists to Inform Task Selection. Abstract P.161 presented at: MDA Clinical and Scientific Conference; 2019 Apr 13; Orlando, Florida."},{"key":"pone.0266845.ref020","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1002\/mus.27335","article-title":"Reliability and construct validity of the Duchenne Video Assessment","volume":"64","author":"MG Contesse","year":"2021","journal-title":"Muscle Nerve"},{"key":"pone.0266845.ref021","volume-title":"The RAND\/UCLA Appropriateness Method User\u2019s Manual.","author":"K Fitch","year":"2001"},{"key":"pone.0266845.ref022","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1186\/s12874-016-0165-8","article-title":"Using the modified Delphi method to establish clinical consensus for the diagnosis and treatment of patients with rotator cuff pathology.","volume":"16","author":"BH Eubank","year":"2016","journal-title":"BMC Medical Research Methodology"},{"key":"pone.0266845.ref023","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1287\/mnsc.9.3.458","article-title":"An Experimental Application of the DELPHI Method to the Use of Experts.","volume":"9","author":"N Dalkey","year":"1963","journal-title":"Management Science"},{"key":"pone.0266845.ref024","doi-asserted-by":"crossref","first-page":"i","DOI":"10.3310\/hta2030","article-title":"Consensus development methods, and their use in clinical guideline development.","volume":"2","author":"MK Murphy","year":"1998","journal-title":"Health Technol Assess."},{"key":"pone.0266845.ref025","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1111\/j.2042-7174.1996.tb00844.x","article-title":"The Delphi and nominal group techniques in health services research","volume":"4","author":"JA Cantrill","year":"1996","journal-title":"International Journal of Pharmacy Practice"},{"key":"pone.0266845.ref026","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1016\/j.gaitpost.2006.04.009","article-title":"Compensatory strategies during normal walking in response to muscle weakness and increased hip joint stiffness.","volume":"25","author":"EJ Goldberg","year":"2007","journal-title":"Gait Posture"},{"key":"pone.0266845.ref027","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1097\/00003677-200304000-00009","article-title":"Toward a Better Understanding of Gait Changes With Age and Disablement: Neuromuscular Adaptation.","volume":"31","author":"CA McGibbon","year":"2003","journal-title":"Exercise and Sport Sciences Reviews."},{"key":"pone.0266845.ref028","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1111\/cts.12834","article-title":"Remote Monitoring in Clinical Trials During the COVID\u201019 Pandemic.","volume":"13","author":"ES Izmailova","year":"2020","journal-title":"Clin Transl Sci."},{"key":"pone.0266845.ref029","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1038\/d41573-020-00094-0","article-title":"Remote digital monitoring in clinical trials in the time of COVID-19","volume":"19","author":"JC Goldsack","year":"2020","journal-title":"Nature Reviews Drug Discovery"},{"key":"pone.0266845.ref030","doi-asserted-by":"crossref","first-page":"1935","DOI":"10.1001\/jama.2021.4609","article-title":"Remote Research and Clinical Trial Integrity During and After the Coronavirus Pandemic","volume":"325","author":"MM McDermott","year":"2021","journal-title":"JAMA"},{"key":"pone.0266845.ref031","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1177\/2168479018764650","article-title":"Unique Burdens of Pediatric Clinical Trials in Duchenne Muscular Dystrophy, April 20\u201321, 2017, Bethesda, Maryland, USA.","volume":"53","author":"T Franson","year":"2019","journal-title":"Ther Innov Regul Sci."}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0266845","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,19]],"date-time":"2023-11-19T23:50:01Z","timestamp":1700437801000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0266845"}},"subtitle":[],"editor":[{"given":"Tai-Heng","family":"Chen","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2022,4,13]]},"references-count":31,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2022,4,13]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0266845","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,4,13]]}}}