{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,30]],"date-time":"2026-03-30T16:50:48Z","timestamp":1774889448294,"version":"3.50.1"},"reference-count":31,"publisher":"Public Library of Science (PLoS)","issue":"6","license":[{"start":{"date-parts":[[2022,6,6]],"date-time":"2022-06-06T00:00:00Z","timestamp":1654473600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002560","name":"Soonchunhyang University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002560","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002461","name":"Chungbuk National University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002461","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\">\n<jats:title>Background<\/jats:title>\n<jats:p>Intraoperative hypertension and blood pressure (BP) fluctuation are known to be associated with negative patient outcomes. During robotic lower abdominal surgery, the patient\u2019s abdominal cavity is filled with CO<jats:sub>2<\/jats:sub>, and the patient\u2019s head is steeply positioned toward the floor (Trendelenburg position). Pneumoperitoneum and the Trendelenburg position together with physiological alterations during anesthesia, interfere with predicting BP changes. Recently, deep learning using recurrent neural networks (RNN) was shown to be effective in predicting intraoperative BP. A model for predicting BP rise was designed using RNN under special scenarios during robotic laparoscopic surgery and its accuracy was tested.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec002\">\n<jats:title>Methods<\/jats:title>\n<jats:p>Databases that included adult patients (over 19 years old) undergoing low abdominal da Vinci robotic surgery (ovarian cystectomy, hysterectomy, myomectomy, prostatectomy, and salpingo-oophorectomy) at Soonchunhyang University Bucheon Hospital from October 2018 to March 2021 were used. An RNN-based model was designed using Python3 language with the PyTorch packages. The model was trained to predict whether hypertension (20% increase in the mean BP from baseline) would develop within 10 minutes after pneumoperitoneum.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec003\">\n<jats:title>Results<\/jats:title>\n<jats:p>Eight distinct datasets were generated and the predictive power was compared. The macro-average F1 scores of the datasets ranged from 68.18% to 72.33%. It took only 3.472 milliseconds to obtain 39 prediction outputs.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec004\">\n<jats:title>Conclusions<\/jats:title>\n<jats:p>A prediction model using the RNN may predict BP rises during robotic laparoscopic surgery.<\/jats:p>\n<\/jats:sec>","DOI":"10.1371\/journal.pone.0269468","type":"journal-article","created":{"date-parts":[[2022,6,6]],"date-time":"2022-06-06T17:28:17Z","timestamp":1654536497000},"page":"e0269468","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":3,"title":["Prediction of blood pressure changes associated with abdominal pressure changes during robotic laparoscopic low abdominal surgery using deep learning"],"prefix":"10.1371","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9823-9030","authenticated-orcid":true,"given":"Yang-Hoon","family":"Chung","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Young-Seob","family":"Jeong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gati Lother","family":"Martin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Min Seo","family":"Choi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"You Jin","family":"Kang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7470-0921","authenticated-orcid":true,"given":"Misoon","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana","family":"Cho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bon Sung","family":"Koo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sung Hwan","family":"Cho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6267-7365","authenticated-orcid":true,"given":"Sang Hyun","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2022,6,6]]},"reference":[{"issue":"2","key":"pone.0269468.ref001","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1213\/00000539-200208000-00003","article-title":"Intraoperative tachycardia and hypertension are independently associated with adverse outcome in noncardiac surgery of long duration","volume":"95","author":"DL Reich","year":"2002","journal-title":"Anesth Analg"},{"issue":"5","key":"pone.0269468.ref002","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1097\/00000539-200205000-00005","article-title":"Isolated systolic hypertension is associated with adverse outcomes from coronary artery bypass grafting surgery","volume":"94","author":"S Aronson","year":"2002","journal-title":"Anesth Analg"},{"issue":"2","key":"pone.0269468.ref003","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1097\/ALN.0000000000000756","article-title":"Association between Intraoperative Hypotension and Hypertension and 30-day Postoperative Mortality in Noncardiac Surgery","volume":"123","author":"TG Monk","year":"2015","journal-title":"Anesthesiology"},{"issue":"5","key":"pone.0269468.ref004","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1007\/s11906-012-0287-2","article-title":"Perioperative hypertension: defining at-risk patients and their management","volume":"14","author":"SF Lien","year":"2012","journal-title":"Curr Hypertens Rep"},{"issue":"1","key":"pone.0269468.ref005","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1097\/ALN.0000000000000686","article-title":"Intraoperative Mean Arterial Pressure Variability and 30-day Mortality in Patients Having Noncardiac Surgery","volume":"123","author":"EJ Mascha","year":"2015","journal-title":"Anesthesiology"},{"issue":"1","key":"pone.0269468.ref006","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1213\/ANE.0b013e31820f9231","article-title":"Does perioperative systolic blood pressure variability predict mortality after cardiac surgery? 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