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Several structural and functional brain alterations have been revealed in this condition, but previous behavioral studies indicated that language systems may also be impaired. We used a silent word generation task to induce brain activation in Broca\u2019s area and other parts of the language system. Blood-oxygen-level-dependent activation analysis and psychophysiological interaction analysis were applied to assess functional brain changes. IUD was measured by the Problematic Internet Use Questionnaire and two additional questions concerning usage time and subjective rating of addiction. According to our key findings, areas strongly related to the default mode network were altered in IUD during the task. Moreover, Broca\u2019s area showed altered functional connectivity with other language network and occipital areas in IUD. These findings may address the neural background of decreased verbal fluency performance previously reported in the literature, and we emphasize that beside the brain\u2019s reward and inhibitory control systems, the language system is the next candidate to be involved in the pathogenesis of IUD.<\/jats:p>","DOI":"10.1371\/journal.pone.0269979","type":"journal-article","created":{"date-parts":[[2022,6,24]],"date-time":"2022-06-24T13:33:16Z","timestamp":1656077596000},"page":"e0269979","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":6,"title":["Language processing in Internet use disorder: Task-based fMRI study"],"prefix":"10.1371","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7042-8059","authenticated-orcid":true,"given":"Gergely","family":"Darnai","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G\u00e1bor","family":"Perlaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9388-2967","authenticated-orcid":true,"given":"Gergely","family":"Orsi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00c1kos","family":"Arat\u00f3","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Szente","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R\u00e9ka","family":"Horv\u00e1th","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eszter","family":"\u00c1fra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Szilvia Anett","family":"Nagy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norbert","family":"Kov\u00e1cs","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tam\u00e1s","family":"D\u00f3czi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00f3zsef","family":"Janszky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2022,6,24]]},"reference":[{"key":"pone.0269979.ref001","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1089\/cpb.1998.1.237","article-title":"Internet Addiction: The Emergence of a New Clinical Disorder.","volume":"1","author":"KS Young","year":"1998","journal-title":"CyberPsychology Behav"},{"key":"pone.0269979.ref002","doi-asserted-by":"crossref","first-page":"563","DOI":"10.3758\/BRM.40.2.563","article-title":"The three-factor model of Internet addiction: The development of the Problematic Internet Use Questionnaire","volume":"40","author":"Z Demetrovics","year":"2008","journal-title":"Behav Res Methods"},{"key":"pone.0269979.ref003","doi-asserted-by":"crossref","first-page":"143","DOI":"10.5498\/wjp.v6.i1.143","article-title":"Internet addiction and problematic Internet use: A systematic review of clinical research","volume":"6","author":"DJ Kuss","year":"2016","journal-title":"World J Psychiatry"},{"key":"pone.0269979.ref004","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1111\/appy.12122","article-title":"Is it meaningful to distinguish between generalized and specific Internet addiction? 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