{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T20:53:52Z","timestamp":1782939232352,"version":"3.54.5"},"reference-count":59,"publisher":"Public Library of Science (PLoS)","issue":"8","license":[{"start":{"date-parts":[[2022,8,4]],"date-time":"2022-08-04T00:00:00Z","timestamp":1659571200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:p>The COVID-19 pandemic is alarmingly a global health catastrophe that has created an unprecedented mental health decline especially in young adults, who have been noted to be a vulnerable population. In this study, we investigated the prevalence of depression and anxiety in university students in China and Africa during the COVID-19 pandemic, the significant factors contributing to the prevalence of anxiety and depression, the differences in factors affecting the different groups being investigated and to emphasize that psychological intervention are as important as the physical interventions during and after the pandemic. The study was conducted through online surveys, with 684 participants using Patient Health Questionnaire-9 and Generalized Anxiety Disorder-7 standardized scales. Comparing all groups combined, of the 636 participants, 361 (56.8%) had depression and 227 (35.7%) had anxiety. Chi squared tests at significance level (P&lt;0.05) showed that country of citizenship, religion, parents\u2019 educational background, household monthly income and, having family members with COVID-19 variables were strongly associated with depression and anxiety. In contrast, age, gender, educational background, and major showed no significant association. Comparing the individual groups separately using chi square (P&lt;0.05), the Chinese students in China group had 35.6% with depression and 13.1% with anxiety. The variable associated with both depression and anxiety was education major, with depression only was parent\u2019s educational background and with anxiety only was gender. The African students in China group had 70.3% with depression and 45.0% with anxiety. Gender was strongly associated with both depression and anxiety, and religion and having family members with COVID-19 with anxiety only. Africans in Africa had 66.0% with depression and 50.5% with anxiety. Educational background was strongly associated with depression. There was no statistically significant variable for anxiety. Chi square test showed a statistically significant difference in depression and anxiety levels with the Chinese group compared to both African groups, and no significant difference between both African groups. Our findings demonstrated that COVID-19 had a negative psychological impact on university students. Therefore, more attention should be put on youth\u2019s mental health during this pandemic.<\/jats:p>","DOI":"10.1371\/journal.pone.0270824","type":"journal-article","created":{"date-parts":[[2022,8,4]],"date-time":"2022-08-04T17:34:36Z","timestamp":1659634476000},"page":"e0270824","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":14,"title":["The psychological impact of COVID-19 on university students in China and Africa"],"prefix":"10.1371","volume":"17","author":[{"given":"Pamela","family":"Marahwa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Panashe","family":"Makota","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donald Tafadzwa","family":"Chikomo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tawanda","family":"Chakanyuka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tsitsi","family":"Ruvai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelvin Stefan","family":"Osafo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tianwen","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1554-4951","authenticated-orcid":true,"given":"Limin","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2022,8,4]]},"reference":[{"key":"pone.0270824.ref001","unstructured":"Naming the coronavirus disease (COVID-19) and the virus that causes it [Internet]. Who.int. [cited 2022 Jun 25]. Available from: https:\/\/www.who.int\/emergencies\/diseases\/novel-coronavirus-2019\/technical-guidance\/naming-the-coronavirus-disease-(covid-2019)-and-the-virus-that-causes-it"},{"issue":"4","key":"pone.0270824.ref002","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1002\/jmv.25693","article-title":"Potential of large \u201cfirst generation\u201d human\u2010to\u2010human transmission of 2019\u2010nCoV.","volume":"92","author":"X Li","year":"2020","journal-title":"J Med Virol [Internet]."},{"issue":"13","key":"pone.0270824.ref003","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.1056\/NEJMoa2001316","article-title":"Early transmission dynamics in Wuhan, China, of novel Coronavirus-infected pneumonia","volume":"382","author":"Q Li","year":"2020","journal-title":"N Engl J Med [Internet]."},{"key":"pone.0270824.ref004","author":"R. 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Solano","year":"2016","journal-title":"Psychiatry Research"},{"key":"pone.0270824.ref016","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.jad.2016.12.003","article-title":"Differential associations of affective temperaments and diagnosis of major affective disorders with suicidal behavior","volume":"210","author":"RJ Baldessarini","year":"2017","journal-title":"J Affect Disord [Internet]."},{"issue":"3","key":"pone.0270824.ref017","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1037\/abn0000410","article-title":"Age, period, and cohort trends in mood disorder indicators and suicide-related outcomes in a nationally representative dataset, 2005\u20132017","volume":"128","author":"J. M. 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Gelaye","year":"2013","journal-title":"Psychiatry Research"},{"key":"pone.0270824.ref025","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.psychres.2018.12.004","article-title":"Psychometric properties of the 7-item Generalized Anxiety Disorder Scale (GAD-7) in a large representative sample of Finnish adolescents.","volume":"272","author":"K Tiirikainen","year":"2019","journal-title":"Psychiatry Res [Internet]"},{"issue":"1","key":"pone.0270824.ref026","doi-asserted-by":"crossref","first-page":"e0245327","DOI":"10.1371\/journal.pone.0245327","article-title":"Psychological impacts from COVID-19 among university students: Risk factors across seven states in the United States","volume":"16","author":"M. H. E. M. Browning","year":"2021","journal-title":"PloS One"},{"issue":"105107","key":"pone.0270824.ref027","doi-asserted-by":"crossref","first-page":"105107","DOI":"10.1016\/j.worlddev.2020.105107","article-title":"Psychological stress responses to COVID-19 and adaptive strategies in China.","volume":"136","author":"M. Song","year":"2020","journal-title":"World Dev [Internet]"},{"issue":"112934","key":"pone.0270824.ref028","doi-asserted-by":"crossref","first-page":"112934","DOI":"10.1016\/j.psychres.2020.112934","article-title":"The psychological impact of the COVID-19 epidemic on college students in China.","volume":"287","author":"W. Cao","year":"2020","journal-title":"Psychiatry Research"},{"key":"pone.0270824.ref029","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.12688\/f1000research.25557.1","article-title":"Coping strategies of students for anxiety during the COVID-19 pandemic in China: a cross-sectional study","volume":"9","author":"M. Nurunnabi","year":"2020","journal-title":"F1000Research"},{"key":"pone.0270824.ref030","first-page":"1","article-title":"Information overload and infodemic in the COVID-19 pandemic","volume":"0","author":"F. Rathore","year":"2020","journal-title":"JPMA. The Journal of the Pakistan Medical Association"},{"key":"pone.0270824.ref031","unstructured":"(N.d.). Who.Int. Retrieved June 25, 2022, from https:\/\/www.afro.who.int\/sites\/default\/files\/2017-06\/english\u2014health_systems_in_africa\u20142012.pdf"},{"key":"pone.0270824.ref032"},{"key":"pone.0270824.ref033","doi-asserted-by":"crossref","first-page":"395","DOI":"10.2147\/IJGM.S223882","article-title":"Identifying key challenges facing healthcare systems in Africa and potential solutions.","volume":"12","author":"OO Oleribe","year":"2019","journal-title":"Int J Gen Med [Internet]"},{"issue":"6","key":"pone.0270824.ref034","doi-asserted-by":"crossref","first-page":"2035","DOI":"10.1002\/hpm.3296","article-title":"COVID\u201019 calls for health systems strengthening in Africa: A case of Nigeria.","volume":"36","author":"E. E. Elebesunu","year":"2021","journal-title":"The International Journal of Health Planning and Management"},{"issue":"4","key":"pone.0270824.ref035","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1007\/BF00896502","article-title":"The epidemiology of economic stress","volume":"12","author":"D. Dooley","year":"1984","journal-title":"American Journal of Community Psychology"},{"key":"pone.0270824.ref036","unstructured":"(N.d.). Unfpa.Org. Retrieved June 25, 2022, from https:\/\/sierraleone.unfpa.org\/sites\/default\/files\/pub-pdf\/EVD%20report.pdf"},{"issue":"1","key":"pone.0270824.ref037","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1186\/s12875-021-01442-8","article-title":"The mental health crises of the families of COVID-19 victims: a qualitative study","volume":"22","author":"F. Mohammadi","year":"2021","journal-title":"BMC Family Practice"},{"key":"pone.0270824.ref038","doi-asserted-by":"crossref","DOI":"10.3389\/fpubh.2021.603331","article-title":"Factors influencing mental health among Chinese medical and non-medical students in the early stage of the COVID-19 pandemic","volume":"9","author":"P. Xiong","year":"2021","journal-title":"Frontiers in Public Health"},{"issue":"8","key":"pone.0270824.ref039","doi-asserted-by":"crossref","first-page":"1445","DOI":"10.1007\/s00038-020-01475-3","article-title":"The immediate psychological effects of Coronavirus Disease 2019 on medical and non-medical students in China.","volume":"65","author":"L. Xie","year":"2020","journal-title":"International Journal of Public Health"},{"issue":"4","key":"pone.0270824.ref040","doi-asserted-by":"crossref","first-page":"965","DOI":"10.3390\/jcm9040965","article-title":"People with suspected COVID-19 symptoms were more likely depressed and had lower health-related quality of life: The potential benefit of health literacy","volume":"9","author":"H. C. Nguyen","year":"2020","journal-title":"Journal of Clinical Medicine"},{"issue":"11","key":"pone.0270824.ref041","doi-asserted-by":"crossref","first-page":"4164","DOI":"10.3390\/ijerph17114164","article-title":"Fear of COVID-19 scale\u2014associations of its scores with health literacy and health-related behaviors among medical students","volume":"17","author":"H. T. Nguyen","year":"2020","journal-title":"International Journal of Environmental Research and Public Health"},{"issue":"102092","key":"pone.0270824.ref042","doi-asserted-by":"crossref","first-page":"102092","DOI":"10.1016\/j.ajp.2020.102092","article-title":"Epidemic of COVID-19 in China and associated Psychological Problems","volume":"51","author":"M. Z. Ahmed","year":"2020","journal-title":"Asian Journal of Psychiatry"},{"issue":"1","key":"pone.0270824.ref043","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1080\/13548506.2020.1746817","article-title":"Study on the public psychological states and its related factors during the outbreak of coronavirus disease 2019 (COVID-19) in some regions of China.","volume":"26","author":"Y. Wang","year":"2021","journal-title":"Psychology, Health & Medicine"},{"key":"pone.0270824.ref044","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1016\/j.jad.2019.11.121","article-title":"Gender differences in depression, anxiety, and stress among college students: A longitudinal study from China","volume":"263","author":"W. Gao","year":"2020","journal-title":"Journal of Affective Disorders"},{"key":"pone.0270824.ref045","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.1002\/cphy.c130054","volume-title":"Comprehensive Physiology","author":"N. Goel","year":"2014"},{"key":"pone.0270824.ref046","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.pneurobio.2019.01.006","article-title":"Sex differences in depression: Insights from clinical and preclinical studies","volume":"176","author":"R. S. Eid","year":"2019","journal-title":"Progress in Neurobiology"},{"issue":"4","key":"pone.0270824.ref047","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1037\/a0020629","article-title":"Gender differences in life events prior to onset of major depressive disorder: the moderat- ing effect of age","volume":"119","author":"K. L. Harkness","year":"2010","journal-title":"J Abnorm Psychol"},{"issue":"7","key":"pone.0270824.ref048","doi-asserted-by":"crossref","first-page":"e019982","DOI":"10.1136\/bmjopen-2017-019982","article-title":"Gender, stressful life events and interactions with sleep: a systematic review of determinants of adiposity in young people","volume":"8","author":"A. I. Conklin","year":"2018","journal-title":"BMJ Open"},{"issue":"100311","key":"pone.0270824.ref049","doi-asserted-by":"crossref","first-page":"100311","DOI":"10.1016\/j.eclinm.2020.100311","article-title":"The impact of gender discrimination on a Woman\u2019s Mental Health","volume":"20","author":"S. N. Vigod","year":"2020","journal-title":"EClinicalMedicine"},{"issue":"10231","key":"pone.0270824.ref050","first-page":"1168","article-title":"The gendered dimensions of COVID-19","volume":"395","author":"The Lancet","year":"2020","journal-title":"Lancet"},{"issue":"11","key":"pone.0270824.ref051","doi-asserted-by":"crossref","first-page":"1140","DOI":"10.1001\/jama.2009.341","article-title":"Religious coping and use of intensive life-prolonging care near death in patients with advanced cancer.","volume":"301","author":"A. C. Phelps","year":"2009","journal-title":"JAMA: The Journal of the American Medical Association"},{"issue":"1","key":"pone.0270824.ref052","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/13674676.2020.1768725","article-title":"COVID-19, mental health and religion: an agenda for future research.","volume":"23","author":"S. 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