{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T09:41:17Z","timestamp":1777023677896,"version":"3.51.4"},"reference-count":39,"publisher":"Public Library of Science (PLoS)","issue":"7","license":[{"start":{"date-parts":[[2022,7,19]],"date-time":"2022-07-19T00:00:00Z","timestamp":1658188800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100010731","name":"Faculty of Medicine, Chiang Mai University","doi-asserted-by":"publisher","award":["010-2562"],"award-info":[{"award-number":["010-2562"]}],"id":[{"id":"10.13039\/501100010731","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:p>Dry eye disease (DED) is a common and growing eye problem worldwide. Chronic DED symptoms can, subsequently, affect the patients\u2019 quality of life (QOL). This prospective cross-sectional study aimed to assess the reliability, validity, and responsiveness of the Thai version of the Dry Eye-Related Quality-of-Life Score (DEQS-Th) questionnaire and to evaluate its accuracy in DED screening. Psychometric validation was conducted on DED participants. All participants completed the DEQS-Th and other measurements including the Ocular Surface Disease Index (OSDI) and the 5-level EQ-5D (EQ-5D-5L). Internal consistency, concurrent validity, convergent, and discriminant validity were evaluated. The standardized response mean (SRM) was used to evaluate the responsiveness of the DEQS-Th. The optimal cut-off score of DEQS-Th for DED screening was assessed. Among 100 participants with a mean age of 50.9 \u00b1 14.4 years, and 89.0% female, the internal consistency of the DEQS-Th was excellent (Cronbach\u2019s alpha: 0.80\u20130.92). The test-retest intraclass correlation was 0.82\u20130.92. It showed concurrent validity with the OSDI (r = 0.694, p &lt; .001) and EQ-5D-5L index scores (r = -0.578, p &lt; .001). DED is suspected if the DEQS-Th score \u2265 18.33 (AUC = 0.897, sensitivity 90.0%, specificity 76.7%) or its Short Form score \u2265 3 (AUC 0.857, sensitivity 93.0%, specificity 63.3%). The SRM of the symptom subscale of DEQS-Th was 0.82, indicating relatively large responsiveness, whereas the impact on daily life subscale and the summary score was small. In conclusion, the DEQS-Th is valid and reliable for evaluating the multifaceted effects of DED on a patient\u2019s QOL. It can be useful for primary assessment and monitoring of DED in routine clinical practice.<\/jats:p>","DOI":"10.1371\/journal.pone.0271228","type":"journal-article","created":{"date-parts":[[2022,7,19]],"date-time":"2022-07-19T17:29:33Z","timestamp":1658251773000},"page":"e0271228","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":11,"title":["Reliability, validity, and responsiveness of the Thai version of the Dry Eye-Related Quality-of-Life Score 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