{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T02:36:05Z","timestamp":1792031765821,"version":"4.4.0"},"reference-count":31,"publisher":"Public Library of Science (PLoS)","issue":"7","license":[{"start":{"date-parts":[[2022,7,8]],"date-time":"2022-07-08T00:00:00Z","timestamp":1657238400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100010049","name":"Ethiopian Public Health Association","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010049","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\"><jats:title>Background<\/jats:title><jats:p>Adverse pregnancy outcomes are the main causes of maternal and neonatal morbidity and mortality and long-term physical and psychological sequels in low- and middle-income countries, particularly in Africa and Asia. In Ethiopia, maternal mortality remained high despite the country\u2019s maximum effort. This study aimed to assess adverse pregnancy outcomes and associated factors among deliveries at Debre Berhan Comprehensive Specialized Hospital, Northeast Ethiopia.<\/jats:p><\/jats:sec><jats:sec id=\"sec002\"><jats:title>Methods<\/jats:title><jats:p>A retrospective cross-sectional study was done among deliveries at Debre Berhan Comprehensive Specialized Hospital from January 1, 2017, to December 31, 2018. The data was collected using a structured and pre-tested questionnaire by reviewing labor and delivery service log books and admission or discharge registration books. The data were entered into a Microsoft Excel spreadsheet and analyzed using SPSS version 25. Logistic regression analysis was computed to identify independent predictors of pregnancy complications.<\/jats:p><\/jats:sec><jats:sec id=\"sec003\"><jats:title>Result<\/jats:title><jats:p>In this study, the magnitude of adverse pregnancy outcomes was 28.3%, 95% CI (25.7\u201330.9). The most frequently recorded obstetric complications were obstructed labor (7.4%), retained placenta (5.3%), and hypertensive disorders of pregnancy (2.4%). Whereas stillbirths (10%), malpresentation (3%), and prematurity (2.3%) frequently occurred fetal\/neonatal complications. There were 29 maternal deaths and the possible causes of death were obstructed labor (51.7%), hemorrhage (44.7%), eclampsia (24.1%), and sepsis (6.9%). Home delivery (AOR (CI = 4.12 (2.30\u20137.15) and low birth weight (AOR (CI = 1.63 (1.36\u20131.96) were significant associates of adverse pregnancy outcomes.<\/jats:p><\/jats:sec><jats:sec id=\"sec004\"><jats:title>Conclusion<\/jats:title><jats:p>The magnitude of adverse pregnancy outcomes was high. Obstructed labor, retained placenta, hypertension in pregnancy, malpresentation, prematurity, and stillbirth are the commonest adverse pregnancy outcomes. Place of delivery and birth weight were independent predictors of adverse pregnancy outcomes. Institutional delivery, early detection and management of complications, and adequate nutrition and weight gain during pregnancy should be encouraged to minimize the risk of adverse pregnancy outcomes.<\/jats:p><\/jats:sec>","DOI":"10.1371\/journal.pone.0271287","type":"journal-article","created":{"date-parts":[[2022,7,8]],"date-time":"2022-07-08T17:54:25Z","timestamp":1657302865000},"page":"e0271287","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":49,"title":["Assessment of the adverse pregnancy outcomes and its associated factors among deliveries at Debre Berhan Comprehensive Specialized Hospital, Northeast Ethiopia"],"prefix":"10.1371","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6288-9771","authenticated-orcid":true,"given":"Mesfin","family":"Tadese","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7272-6351","authenticated-orcid":true,"given":"Kefyalew","family":"Dagne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abate Dargie","family":"Wubetu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiferaw","family":"Abeway","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alemayehu","family":"Bekele","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Worku","family":"Misganaw Kebede","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Getaneh","family":"Baye Mulu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2022,7,8]]},"reference":[{"issue":"1","key":"pone.0271287.ref001","doi-asserted-by":"crossref","first-page":"10","DOI":"10.69614\/ejrh.v11i1.235","article-title":"Determinants of adverse pregnancy outcomes among mothers who gave birth from jan 1-dec 31\/2015 in jimma university specialized hospital, case control study, 2016","volume":"11","author":"E. 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Notes"},{"issue":"2","key":"pone.0271287.ref019","doi-asserted-by":"crossref","first-page":"e06323","DOI":"10.1016\/j.heliyon.2021.e06323","article-title":"Predictors of adverse pregnancy outcome at Hospitals in South Gondar Zone, North-central Ethiopia: A multicenter facility-based unmatched case-control study","volume":"7","author":"D. Addisu","year":"2021","journal-title":"Heliyon"},{"key":"pone.0271287.ref020","unstructured":"\u201cDebre Birhan\u2014Wikipedia.\u201d https:\/\/en.wikipedia.org\/wiki\/Debre_Birhan (accessed Mar. 31, 2022)."},{"key":"pone.0271287.ref021","doi-asserted-by":"crossref","first-page":"6539","DOI":"10.2147\/IJGM.S333033","article-title":"Adverse Perinatal Outcomes Among Grand Multiparous and Low Multiparous Women and Its Associated Factors in North Shewa Zone Public Hospitals: The Role of Parity","volume":"14","author":"M. Tadese","year":"2021","journal-title":"Int. J. Gen. 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Getiye","year":"2017","journal-title":"BMC Pregnancy Childbirth"},{"issue":"1","key":"pone.0271287.ref031","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13104-018-3568-2","article-title":"Determinants of low birth weight among neonates born in Amhara Regional State Referral Hospitals of Ethiopia: unmatched case control study","volume":"11","author":"G. Asmare","year":"2018","journal-title":"BMC Res. Notes"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0271287","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,28]],"date-time":"2024-09-28T20:40:45Z","timestamp":1727556045000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0271287"}},"subtitle":[],"editor":[{"given":"Ammal Mokhtar","family":"Metwally","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2022,7,8]]},"references-count":31,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2022,7,8]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0271287","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,7,8]]}}}