{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T17:39:53Z","timestamp":1793209193830,"version":"4.5.0"},"reference-count":43,"publisher":"Public Library of Science (PLoS)","issue":"10","license":[{"start":{"date-parts":[[2022,10,7]],"date-time":"2022-10-07T00:00:00Z","timestamp":1665100800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000865","name":"Bill and Melinda Gates Foundation","doi-asserted-by":"publisher","award":["OPP1107597"],"award-info":[{"award-number":["OPP1107597"]}],"id":[{"id":"10.13039\/100000865","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Cnpq","award":["401615\/2013-8"],"award-info":[{"award-number":["401615\/2013-8"]}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\">\n<jats:title>Objective<\/jats:title>\n<jats:p>Since there are populational differences and risk factors that influence the cervical length, the aim of the study was to construct a populational curve with measurements of the uterine cervix of pregnant women in the second trimester of pregnancy and to evaluate which variables were related to cervical length (CL) \u226425 mm.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec002\">\n<jats:title>Materials and methods<\/jats:title>\n<jats:p>This was a multicenter cross-sectional study performed at 17 hospitals in several regions of Brazil. From 2015 to 2019, transvaginal ultrasound scan was performed in women with singleton pregnancies at 18 0\/7 to 22 6\/7 weeks of gestation to measure the CL. We analyzed CL regarding its distribution and the risk factors for CL \u226425 mm using logistic regression.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec003\">\n<jats:title>Results<\/jats:title>\n<jats:p>The percentage of CL \u2264 25mm was 6.67%. Shorter cervices, when measured using both straight and curve techniques, showed similar results: range 21.0\u201325.0 mm in straight versus 22.6\u201326.0 mm in curve measurement for the 5<jats:sup>th<\/jats:sup> percentile. However, the difference between the two techniques became more pronounced after the 75<jats:sup>th<\/jats:sup> percentile (range 41.0\u201342.0 mm straight x 43.6\u201345.0 mm in curve measurement). The risk factors identified for short cervix were low body mass index (BMI) (OR: 1.81 CI: 1.16\u20132.82), higher education (OR: 1.39 CI: 1.10\u20131.75) and personal history ([one prior miscarriage OR: 1.41 CI: 1.11\u20131.78 and \u22652 prior miscarriages OR: 1.67 CI: 1.24\u20132.25], preterm birth [OR: 1.70 CI: 1.12\u20132.59], previous low birth weight &lt;2500 g [OR: 1.70 CI: 1.15\u20132.50], cervical surgery [OR: 4.33 CI: 2.58\u20137.27]). By contrast, obesity (OR: 0.64 CI: 0.51\u20130.82), living with a partner (OR: 0.76 CI: 0.61\u20130.95) and previous pregnancy (OR: 0.46 CI: 0.37\u20130.57) decreased the risk of short cervix.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec004\">\n<jats:title>Conclusions<\/jats:title>\n<jats:p>The CL distribution showed a relatively low percentage of cervix \u226425 mm. There may be populational differences in the CL distribution and this as well as the risk factors for short CL need to be considered when adopting a screening strategy for short cervix.<\/jats:p>\n<\/jats:sec>","DOI":"10.1371\/journal.pone.0272128","type":"journal-article","created":{"date-parts":[[2022,10,7]],"date-time":"2022-10-07T17:37:26Z","timestamp":1665164246000},"page":"e0272128","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":3,"title":["Cervical length distribution among Brazilian pregnant population and risk factors for short cervix: A multicenter cross-sectional study"],"prefix":"10.1371","volume":"17","author":[{"given":"Kaline Gomes Ferrari","family":"Marquart","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8718-5372","authenticated-orcid":true,"given":"Thais Valeria","family":"Silva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ben W.","family":"Mol","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Guilherme","family":"Cecatti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renato","family":"Passini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cynara M.","family":"Pereira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tha\u00edsa B.","family":"Guedes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatiana F.","family":"Fanton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5739-0009","authenticated-orcid":true,"given":"Rodolfo C.","family":"Pacagnella","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"The P5 working group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2022,10,7]]},"reference":[{"issue":"3","key":"pone.0272128.ref001","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1016\/0002-9378(90)91084-P","article-title":"Prediction of risk for preterm delivery by ultrasonographic measurement of cervical length.","volume":"163","author":"HF Andersen","year":"1990","journal-title":"Am J Obstet Gynecol"},{"issue":"9","key":"pone.0272128.ref002","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1056\/NEJM199602293340904","article-title":"The length of the cervix and the risk of spontaneous premature delivery. 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