{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T02:15:27Z","timestamp":1793758527086,"version":"4.6.1"},"reference-count":33,"publisher":"Public Library of Science (PLoS)","issue":"8","license":[{"start":{"date-parts":[[2022,8,4]],"date-time":"2022-08-04T00:00:00Z","timestamp":1659571200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:p>In December 2020, UNAIDS released a new set of ambitious targets calling for 95% of all people living with HIV to know their HIV status, 95% of all people with diagnosed HIV infection to receive sustained antiretroviral therapy, and 95% of all people receiving antiretroviral therapy to have viral suppression by 2025. Adopted by United Nations Member states in June 2021 as part of the new Political Declaration on HIV and AIDS, these targets, combined with ambitious primary prevention targets and focused attention to supporting enablers, aim to bridge inequalities in treatment coverage and outcomes and accelerate HIV incidence reductions by focusing on progress in all sub-populations, age groups and geographic settings. Here we summarise the evidence and decisions underpinning the new global targets.<\/jats:p>","DOI":"10.1371\/journal.pone.0272405","type":"journal-article","created":{"date-parts":[[2022,8,4]],"date-time":"2022-08-04T13:37:57Z","timestamp":1659620277000},"page":"e0272405","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":443,"title":["Achieving the 95 95 95 targets for all: A pathway to ending AIDS"],"prefix":"10.1371","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2089-7818","authenticated-orcid":true,"given":"Luisa","family":"Frescura","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Godfrey-Faussett","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Feizzadeh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wafaa","family":"El-Sadr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Omar","family":"Syarif","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter D.","family":"Ghys","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"on behalf of the 2025 testing treatment target Working Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2022,8,4]]},"reference":[{"key":"pone.0272405.ref001","author":"UNAIDS","year":"2014","journal-title":"90-90-90 An ambitious treatment target to help end the AIDS epidemic"},{"key":"pone.0272405.ref002","volume-title":"Fast-Track\u2014Ending the AIDS epidemic by 2030","author":"UNAIDS","year":"2014"},{"key":"pone.0272405.ref003","author":"WH Organization","year":"2003","journal-title":"Treat 3 Million by 2005 Initiative.Treating 3 million by 2005: making it happen: the WHO strategy: the WHO and UNAIDS global initiative to provideantiretroviral therapy to 3 million people with HIV\/AIDS in developing countries by the end of 2005"},{"key":"pone.0272405.ref004","unstructured":"UNAIDS. Confronting inequalities: Lessons for pandemic responsesfrom 40 years of AIDS. Global AIDS Update 2021. Geneva: 2021."},{"issue":"9657","key":"pone.0272405.ref005","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/S0140-6736(08)61697-9","article-title":"Universal voluntary HIV testing with immediate antiretroviral therapy as a strategy for elimination of HIV transmission: a mathematical model","volume":"373","author":"RM Granich","year":"2009","journal-title":"Lancet"},{"issue":"5","key":"pone.0272405.ref006","doi-asserted-by":"crossref","first-page":"e284","DOI":"10.1016\/S2352-3018(20)30315-5","article-title":"Trends in knowledge of HIV status and efficiency of HIV testing services in sub-Saharan Africa, 2000\u201320: a modelling study using survey and HIV testing programme data","volume":"8","author":"K Gigu\u00e8re","year":"2021","journal-title":"Lancet HIV"},{"key":"pone.0272405.ref007","unstructured":"Nations U. 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An example of analysing patterns of HIV spreading using incidence-to-prevalence ratios","volume":"20","author":"PJ White","year":"2006","journal-title":"AIDS"},{"issue":"12","key":"pone.0272405.ref019","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1258\/0956462042563639","article-title":"Utilizing HIV transmission rates to assist in prioritizing HIV prevention services","volume":"15","author":"DR Holtgrave","year":"2004","journal-title":"Int J STD AIDS"},{"key":"pone.0272405.ref020","author":"UNAIDS","year":"2018","journal-title":"Miles to Go: Global AIDS Update 2018"},{"key":"pone.0272405.ref021","unstructured":"UNAIDS. UNAIDS epidemiologic estimates 2021. 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