{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,21]],"date-time":"2025-09-21T18:12:41Z","timestamp":1758478361144,"version":"3.40.5"},"reference-count":60,"publisher":"Public Library of Science (PLoS)","issue":"1","license":[{"start":{"date-parts":[[2023,1,17]],"date-time":"2023-01-17T00:00:00Z","timestamp":1673913600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\">\n<jats:title>Introduction<\/jats:title>\n<jats:p>The use of antenatal care by pregnant women enables them to receive good pregnancy monitoring. This monitoring includes counseling, health instructions, examinations and tests to avoid pregnancy-related complications or death during childbirth. To avoid these complications, the World Health Organization (WHO) recommends at least four antenatal visits. Therefore, this study was conducted to identify predictive factors of antenatal care (ANC) among women aged 15 to 49 years and its spatial distribution in Burundi.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec002\">\n<jats:title>Methods<\/jats:title>\n<jats:p>We used data from the Second Burundi Demographic and Health Survey (DHS). A Spatial analysis of ANC prevalence and Mulitlevel logistic regressions of determinants factors of ANC with a medical doctor were done. The ANC prevalence was mapped by region and by province. In unsampled data points, a cluster based interpolation of ANC prevalence was done using the kernel method with an adaptive window. Predictive factors of ANC were assessed using Mulitlevel logistic regressions. The dependent variable was antenatal care with a medical doctor and the explanatory variables were place of residence, age, education level, religion, marital status of the woman, household wealth index and delivery place of the woman. Data processing and data analysis were done using using Quantum Geographic Information System (QGIS) and R software, version 3. 5. 0.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec003\">\n<jats:title>Results<\/jats:title>\n<jats:p>The ANC prevalence varied from 0. 0 to 16. 2% with a median of 0. 5%. A highest predicted ANC prevalence was observed at Muyinga and Kirundo provinces\u2019 junction. Low prevalence was observed in several locations in all regions and provinces. The woman\u2019s education level and delivery place were significantly associated with antenatal care with a medical doctor.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec004\">\n<jats:title>Conclusion<\/jats:title>\n<jats:p>Globally, the ANC prevalence is low in Burundi. It varies across the country. There is an intra-regional or intra-provincial heterogeneity in term of ANC prevalence. Woman\u2019s education level and delivery place are significantly associated antenatal care. There is a need to consider these ANC disparities and factors in the design and strengthening of existing interventions aimed at increasing ANC visits.<\/jats:p>\n<\/jats:sec>","DOI":"10.1371\/journal.pone.0272897","type":"journal-article","created":{"date-parts":[[2023,1,17]],"date-time":"2023-01-17T18:30:57Z","timestamp":1673980257000},"page":"e0272897","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":5,"title":["Spatial distribution and predictive factors of antenatal care in Burundi: A spatial and multilevel baseline analysis for the third burundian demographic and health survey"],"prefix":"10.1371","volume":"18","author":[{"given":"Emmanuel","family":"Barankanira","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0995-800X","authenticated-orcid":true,"given":"Arnaud","family":"Iradukunda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nestor","family":"Ntakaburimvo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Willy","family":"Ahishakiye","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean Claude","family":"Nsavyimana","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emmanuel Nene","family":"Odjidja","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2023,1,17]]},"reference":[{"volume-title":"Maternal mortality: evidence brief","year":"2019","author":"Organization, W. H.","key":"pone.0272897.ref001"},{"key":"pone.0272897.ref002","unstructured":"Organization, W. H., Trends in maternal mortality 2000 to 2017: estimates by WHO, UNICEF, UNFPA, World Bank Group and the United Nations Population Division. 2019."},{"issue":"1","key":"pone.0272897.ref003","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12884-019-2202-1","article-title":"Causes and contributory factors of maternal mortality: evidence from maternal and perinatal death surveillance and response in Ogun state, Southwest Nigeria","volume":"19","author":"R. Sageer","year":"2019","journal-title":"BMC pregnancy and childbirth"},{"issue":"1","key":"pone.0272897.ref004","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.whi.2017.10.007","article-title":"Sexual and reproductive health services and related health information on pregnancy resource center websites: a statewide content analysis","volume":"28","author":"A. Swartzendruber","year":"2018","journal-title":"Women\u2019s Health Issues"},{"issue":"4","key":"pone.0272897.ref005","doi-asserted-by":"crossref","first-page":"e0214848","DOI":"10.1371\/journal.pone.0214848","article-title":"Factors affecting utilization of antenatal care in Ethiopia: a systematic review and meta-analysis","volume":"14","author":"T. Tekelab","year":"2019","journal-title":"PloS one"},{"issue":"1","key":"pone.0272897.ref006","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12978-018-0542-3","article-title":"Determinants of antenatal care attendance among women residing in highly disadvantaged communities in northern Jordan: a cross-sectional study","volume":"15","author":"H. H. Hijazi","year":"2018","journal-title":"Reproductive health"},{"key":"pone.0272897.ref007","first-page":"1","article-title":"Investigating Spatial Patterns and Determinants of Optimal Antenatal Care Attendance Among Pregnant Women in Nigeria","author":"P. Olopha","year":"2021","journal-title":"Spatial Demography"},{"issue":"6","key":"pone.0272897.ref008","doi-asserted-by":"crossref","first-page":"e0217386","DOI":"10.1371\/journal.pone.0217386","article-title":"Understanding the determinants of maternal mortality: An observational study using the Indonesian Population Census","volume":"14","author":"L. Cameron","year":"2019","journal-title":"PloS one"},{"issue":"2","key":"pone.0272897.ref009","doi-asserted-by":"crossref","first-page":"e0192428","DOI":"10.1371\/journal.pone.0192428","article-title":"Antenatal care service quality increases the odds of utilizing institutional delivery in Bahir Dar city administration, North Western Ethiopia: a prospective follow up study","volume":"13","author":"T. Ejigu Tafere","year":"2018","journal-title":"PloS one"},{"issue":"1","key":"pone.0272897.ref010","doi-asserted-by":"crossref","first-page":"1","DOI":"10.4103\/0970-0218.170955","article-title":"Millennium development goals (MDGS) to sustainable development goals (SDGS): Addressing unfinished agenda and strengthening sustainable development and partnership","volume":"41","author":"S. Kumar","year":"2016","journal-title":"Indian journal of community medicine: official publication of Indian Association of Preventive & Social Medicine"},{"issue":"1","key":"pone.0272897.ref011","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12913-015-0943-8","article-title":"Determinants of maternal health services utilization in Uganda","volume":"15","author":"G. Rutaremwa","year":"2015","journal-title":"BMC health services research"},{"issue":"2","key":"pone.0272897.ref012","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1080\/03630242.2014.979971","article-title":"Individual and contextual determinants of adequate maternal health care services in Kenya","volume":"55","author":"T. N. Achia","year":"2015","journal-title":"Women & health"},{"issue":"1","key":"pone.0272897.ref013","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12884-021-04162-0","article-title":"Empirical analysis of socio-economic determinants of maternal health services utilisation in Burundi","volume":"21","author":"D. Habonimana","year":"2021","journal-title":"BMC Pregnancy and Childbirth"},{"issue":"1","key":"pone.0272897.ref014","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12913-020-05516-8","article-title":"Inequalities in caesarean section in Burundi: evidence from the Burundi demographic and health surveys (2010\u20132016)","volume":"20","author":"S. Yaya","year":"2020","journal-title":"BMC Health Services Research"},{"key":"pone.0272897.ref015","unstructured":"Minist\u00e8re \u00e0 la Pr\u00e9sidence charg\u00e9 de la Bonne Gouvernance et du Plan, M. d. l. S. P. e. d. l. L. C. l. S., Institut de Statistiques et d\u2019\u00c9tudes \u00c9conomiques du Burundi, ICF, Troisi\u00e8me Enqu\u00eate D\u00e9mographique et de Sant\u00e9 au Burundi 2016\u20132017. 2017, ISTEEBU, MSPLS, and ICF Bujumbura, Burundi."},{"key":"pone.0272897.ref016","unstructured":"Burundi., I. d. S. e. d. \u00c9. \u00c9. d., Enqu\u00eate d\u00e9mographique et de sant\u00e9 Burundi 2010. 2012."},{"key":"pone.0272897.ref017","doi-asserted-by":"crossref","unstructured":"Zhu, B., et al. Cross-domain empirical risk minimization for unbiased long-tailed classification. in Proceedings of the AAAI Conference on Artificial Intelligence. 2022.","DOI":"10.1609\/aaai.v36i3.20271"},{"key":"pone.0272897.ref018","doi-asserted-by":"crossref","first-page":"863","DOI":"10.3389\/fpsyg.2013.00863","article-title":"Calculating and reporting effect sizes to facilitate cumulative science: a practical primer for t-tests and ANOVAs","volume":"4","author":"D. Lakens","year":"2013","journal-title":"Frontiers in psychology"},{"issue":"5","key":"pone.0272897.ref019","doi-asserted-by":"crossref","first-page":"1110","DOI":"10.1111\/1475-6773.13163","article-title":"Determinants of antenatal care and skilled birth attendance in sub\u2010Saharan Africa: A multilevel analysis","volume":"54","author":"M. A. Woldegiorgis","year":"2019","journal-title":"Health services research"},{"key":"pone.0272897.ref020","article-title":"Factors associated with antenatal care service utilization among women with children under five years in Sunyani Municipality, Ghana","author":"S. S. Owusu","year":"2021","journal-title":"medRxiv"},{"issue":"1","key":"pone.0272897.ref021","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12884-020-03489-4","article-title":"Determinants of antenatal care and skilled birth attendance services utilization among childbearing women in Guinea: evidence from the 2018 Guinea Demographic and Health Survey data","volume":"21","author":"B. O. Ahinkorah","year":"2021","journal-title":"BMC Pregnancy and Childbirth"},{"key":"pone.0272897.ref022","article-title":"Factors Associated with Antenatal Care Service Utilization among Mothers with Children under five years in Sunyani Municipality, Ghana","author":"S. O. Sekyere","year":"2021","journal-title":"medRxiv"},{"issue":"2","key":"pone.0272897.ref023","doi-asserted-by":"crossref","first-page":"e001341","DOI":"10.1136\/bmjgh-2018-001341","article-title":"Socioeconomic factors associated with choice of delivery place among mothers: a population-based cross-sectional study in Guinea-Bissau","volume":"4","author":"S. Yaya","year":"2019","journal-title":"BMJ global health"},{"issue":"1","key":"pone.0272897.ref024","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12889-021-10884-9","article-title":"Exploring antenatal care utilization and intimate partner violence in Benin-are lives at stake?","volume":"21","author":"D. Idriss-Wheeler","year":"2021","journal-title":"BMC public health"},{"key":"pone.0272897.ref025","first-page":"1","article-title":"Predictors of Antenatal Care Utilization in Primary Healthcare Centers in Eight Rural Communities in Delta State, Nigeria","volume":"8","author":"R. R. Ahuru","year":"2019","journal-title":"African Journal of Health Economics"},{"issue":"1","key":"pone.0272897.ref026","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12884-019-2259-x","article-title":"Determinants of utilization of antenatal care services in Benishangul Gumuz Region, Western Ethiopia: a study based on demographic and health survey","volume":"19","author":"K. Tiruaynet","year":"2019","journal-title":"BMC pregnancy and childbirth"},{"key":"pone.0272897.ref027","doi-asserted-by":"crossref","unstructured":"Bolarinwa, O. A., et al. Spatial Patterns and Multilevel Analysis of Factors Associated with Antenatal Care Visits in Nigeria: Insight from the 2018 Nigeria Demographic Health Survey. in Healthcare. 2021. MDPI.","DOI":"10.3390\/healthcare9101389"},{"issue":"64","key":"pone.0272897.ref028","doi-asserted-by":"crossref","first-page":"3172","DOI":"10.21105\/joss.03172","article-title":"Semi-Automatic Classification Plugin: A Python tool for the download and processing of remote sensing images in QGIS","volume":"6","author":"L. Congedo","year":"2021","journal-title":"Journal of Open Source Software"},{"key":"pone.0272897.ref029","unstructured":"Quantum, G., Development Team (2012) QGIS. Quantum GIS Geographic Information System. Open Source Geospatial Foundation Project, 2019."},{"key":"pone.0272897.ref030","unstructured":"Team, R. C., R: A language and environment for statistical computing. 2013."},{"key":"pone.0272897.ref031","doi-asserted-by":"crossref","unstructured":"Larmarange, J., et al., Methods for mapping regional trends of HIV prevalence from demographic and health surveys (DHS). Cybergeo. 2011.","DOI":"10.4000\/cybergeo.24606"},{"key":"pone.0272897.ref032","unstructured":"Larmarange, J., Developing subnational estimates of HIV prevalence and the number of people living with HIV\u2013Joseph Larmarange. 2021."},{"key":"pone.0272897.ref033","unstructured":"Meda, N., Methods for mapping regional trends of HIV prevalence from Demographic and Health Surveys (DHS)."},{"key":"pone.0272897.ref034","article-title":"Parsimony in model selection: Tools for assessing fit propensity","author":"C. F. Falk","year":"2021","journal-title":"Psychological Methods"},{"issue":"1","key":"pone.0272897.ref035","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12889-021-12233-2","article-title":"Key factors influencing multidrug-resistant tuberculosis in patients under anti-tuberculosis treatment in two centres in Burundi: a mixed effect modelling study","volume":"21","author":"A. Iradukunda","year":"2021","journal-title":"BMC public health"},{"key":"pone.0272897.ref036","first-page":"9","article-title":"Effect of testing logistic regression assumptions on the improvement of the propensity scores","volume":"8","author":"P. Josephat","year":"2018","journal-title":"Int. J. Stat. Appl"},{"issue":"12","key":"pone.0272897.ref037","doi-asserted-by":"crossref","first-page":"e0260225","DOI":"10.1371\/journal.pone.0260225","article-title":"Prevalence and predictive risk factors of hypertension in patients hospitalized in Kamenge Military hospital and Kamenge University teaching hospital in 2019: A fixed effect modelling study in Burundi","volume":"16","author":"A. Iradukunda","year":"2021","journal-title":"PloS one"},{"key":"pone.0272897.ref038","doi-asserted-by":"crossref","unstructured":"Hailegebreal, S., et al., Spatial distribution and associated factors of antenatal care utilization in Ethiopia in 2019: Spatial and multilevel analysis. 2021.","DOI":"10.21203\/rs.3.rs-537337\/v1"},{"issue":"7","key":"pone.0272897.ref039","first-page":"1","article-title":"Prevalence of Antenatal Care Services Satisfaction among Mothers Attending Antenatal Care in Goba Hospital, Bale Zone, Oromia Region, Southeast Ethiopia","volume":"15","author":"A. Y. Mohammed","year":"2021","journal-title":"Health Science Journal"},{"issue":"2","key":"pone.0272897.ref040","doi-asserted-by":"crossref","first-page":"e0224006","DOI":"10.1371\/journal.pone.0224006","article-title":"Regional disparities in antenatal care utilization in Indonesia","volume":"15","author":"A. D. Laksono","year":"2020","journal-title":"PLoS One"},{"issue":"4","key":"pone.0272897.ref041","first-page":"69","article-title":"Exploring determinants influencing the utilisation of antenatal care in Indonesia: A narrative systematic review","volume":"2","author":"A. D. Damayani","year":"2017","journal-title":"ARCHIVOS DE MEDICINA"},{"issue":"5","key":"pone.0272897.ref042","doi-asserted-by":"crossref","first-page":"e0197324","DOI":"10.1371\/journal.pone.0197324","article-title":"Prevalence and factors associated with underutilization of antenatal care services in Nigeria: A comparative study of rural and urban residences based on the 2013 Nigeria demographic and health survey","volume":"13","author":"E. O. Adewuyi","year":"2018","journal-title":"PloS one"},{"issue":"1","key":"pone.0272897.ref043","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12884-020-2795-4","article-title":"Spatial distribution and determinants of an optimal ANC visit among pregnant women in Ethiopia: further analysis of 2016 Ethiopia demographic health survey","volume":"20","author":"Z. T. Tessema","year":"2020","journal-title":"BMC pregnancy and childbirth"},{"issue":"1","key":"pone.0272897.ref044","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12978-018-0556-x","article-title":"Inequities in maternal health services utilization in Ethiopia 2000\u20132016: magnitude, trends, and determinants","volume":"15","author":"E. Gebre","year":"2018","journal-title":"Reproductive health"},{"issue":"1","key":"pone.0272897.ref045","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12884-021-03607-w","article-title":"Maternal health care service utilization among young married women in India, 1992\u20132016: trends and determinants","volume":"21","author":"P. Singh","year":"2021","journal-title":"BMC Pregnancy and Childbirth"},{"issue":"1","key":"pone.0272897.ref046","doi-asserted-by":"crossref","first-page":"89","DOI":"10.20473\/jaki.v7i1.2019.89-98","article-title":"Inspecting primary healthcare centers in remote areas: Facilities, activities, and finances","volume":"7","author":"P. Soewondo","year":"2019","journal-title":"Jurnal Administrasi Kesehatan Indonesia"},{"issue":"1","key":"pone.0272897.ref047","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12884-018-1874-2","article-title":"Spatial distribution of antenatal care utilization and associated factors in Ethiopia: evidence from Ethiopian demographic health surveys","volume":"18","author":"A. Yeneneh","year":"2018","journal-title":"BMC pregnancy and childbirth"},{"issue":"2","key":"pone.0272897.ref048","doi-asserted-by":"crossref","first-page":"e013408","DOI":"10.1136\/bmjopen-2016-013408","article-title":"Regional differences in usage of antenatal care and safe delivery services in Indonesia: findings from a nationally representative survey","volume":"7","author":"V. Tripathi","year":"2017","journal-title":"BMJ open"},{"key":"pone.0272897.ref049","doi-asserted-by":"crossref","DOI":"10.1155\/2020\/9592124","article-title":"Quality of prenatal care and associated factors among pregnant women at public health facilities of Wogera District, Northwest Ethiopia","volume":"2020","author":"A. Kassaw","year":"2020","journal-title":"Journal of pregnancy"},{"issue":"1","key":"pone.0272897.ref050","doi-asserted-by":"crossref","first-page":"77","DOI":"10.15406\/ogij.2020.11.00492","article-title":"Determinants of antenatal care visits and their impact on the choice of birthplace among mothers in Uganda: a systematic review","volume":"11","author":"S. Atuhaire","year":"2020","journal-title":"Obstet Gynecol Int J"},{"issue":"1","key":"pone.0272897.ref051","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12939-015-0162-2","article-title":"Factors influencing the use of maternal healthcare services and childhood immunization in Swaziland","volume":"14","author":"M. Tsawe","year":"2015","journal-title":"International journal for equity in health"},{"key":"pone.0272897.ref052","unstructured":"Mwebesa, E., Multilevel Models for Determinants of Maternal Health Services Utilization in Uganda Using 2016 DHS Data. 2021, Makerere University."},{"issue":"1","key":"pone.0272897.ref053","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1177\/10105395211051237","article-title":"The determinants of four or more antenatal care visits among working women in Indonesia","volume":"34","author":"H. M. Denny","year":"2022","journal-title":"Asia Pacific Journal of Public Health"},{"issue":"1","key":"pone.0272897.ref054","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12978-022-01365-2","article-title":"Determinants of optimal antenatal care visit among pregnant women in Ethiopia: a multilevel analysis of Ethiopian mini demographic health survey 2019 data","volume":"19","author":"D. E. Yehualashet","year":"2022","journal-title":"Reproductive Health"},{"issue":"2","key":"pone.0272897.ref055","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1007\/s40980-021-00083-w","article-title":"Investigating Spatial Patterns and Determinants of Optimal Antenatal Care Attendance Among Pregnant Women in Nigeria","volume":"10","author":"P. Olopha","year":"2022","journal-title":"Spatial Demography"},{"key":"pone.0272897.ref056","doi-asserted-by":"crossref","DOI":"10.1155\/2021\/6623009","article-title":"Utilization and Determinants of Antenatal Care Visits in East African Countries: A Multicountry Analysis of Demographic and Health Surveys","volume":"2021","author":"Z. T. Tessema","year":"2021","journal-title":"Advances in Public Health"},{"key":"pone.0272897.ref057","doi-asserted-by":"crossref","first-page":"100771","DOI":"10.1016\/j.cegh.2021.100771","article-title":"Trends, regional inequalities and determinants in the utilization of prenatal care and skilled birth attendant in Ethiopia: A multilevel analysis","volume":"11","author":"B. T. Woldeamanuel","year":"2021","journal-title":"Clinical Epidemiology and Global Health"},{"key":"pone.0272897.ref058","unstructured":"Ho, G., Women\u2019s knowledge and its associated factors regarding optimum utilisation of antenatal care in rural Ghana: a cross-sectional study."},{"key":"pone.0272897.ref059","doi-asserted-by":"crossref","first-page":"211","DOI":"10.3389\/fpubh.2020.00211","article-title":"Antenatal Care Initiation Among Pregnant Women in the United Arab Emirates: The Mutaba\u2019ah Study","volume":"8","author":"N. Ali","year":"2020","journal-title":"Frontiers in Public Health"},{"issue":"3","key":"pone.0272897.ref060","first-page":"1","article-title":"Factors Associated with First Antenatal Care Booking among Pregnant Women at a Reproductive Health Clinic in Tanzania: A Cross Sectional Study","volume":"9","author":"L. Kisaka","year":"2020","journal-title":"EC Gynaecology"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0272897","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,1,17]],"date-time":"2023-01-17T18:32:04Z","timestamp":1673980324000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0272897"}},"subtitle":[],"editor":[{"given":"Mary Hamer","family":"Hodges","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2023,1,17]]},"references-count":60,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2023,1,17]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0272897","relation":{},"ISSN":["1932-6203"],"issn-type":[{"type":"electronic","value":"1932-6203"}],"subject":[],"published":{"date-parts":[[2023,1,17]]}}}