{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T03:23:30Z","timestamp":1787887410193,"version":"build-2784847793"},"reference-count":18,"publisher":"Public Library of Science (PLoS)","issue":"9","license":[{"start":{"date-parts":[[2022,9,22]],"date-time":"2022-09-22T00:00:00Z","timestamp":1663804800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\">\n<jats:title>Background and purpose<\/jats:title>\n<jats:p>Spinal cord infarction (SCI) is difficult to diagnosis using MRI findings. We aimed to suggest the optimal timing of MRI studies for diagnosing SCI.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec002\">\n<jats:title>Materials and methods<\/jats:title>\n<jats:p>This retrospective study was approved by our institutional review board. The requirement for informed consent was waived. MRI scans of SCI patients diagnosed between January 2015 and August 2019 were enrolled in the SCI group and subdivided according to the interval between symptom onset and time of MRI scan (A, within 6 h; B, 6\u201312 hours; C, 12\u201324 hours; D, 24\u201372 hours; E, 3\u20137 days). Three radiologists analyzed the T2WI scans and evaluated the confidence level of diagnosing SCI using a five-point Likert scale: 1, certainly not; 2, probably not; 3, equivocal; 4, probably yes; 5, certainly yes. Scores of 4 and 5 were defined as \u201cT2WI-positive SCI\u201d and scores of 1\u20133 were defined as \u201cT2WI-negative SCI\u201d.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec003\">\n<jats:title>Results<\/jats:title>\n<jats:p>The SCI group included 58 MRI scans of 34 patients (mean age, 60.6 \u00b1 14.0 years; 18 women). The T2WI positivity rate was 72.4% (42\/58). In contrast to the other subgroups, subgroup A included fewer cases of T2WI-positive SCI (1\/4, 25%) than T2WI-negative SCI. A confidence score of 5 was the most common in subgroup D (4\/27, 14.8%). Among the 12 patients who underwent MRI studies more than twice, confidence scores increased with time.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec004\">\n<jats:title>Conclusion<\/jats:title>\n<jats:p>In patients with suspected SCI showing equivocal initial MRI findings, follow-up MRI studies are helpful, especially when performed between 24 and 72 hours after symptom onset.<\/jats:p>\n<\/jats:sec>","DOI":"10.1371\/journal.pone.0274821","type":"journal-article","created":{"date-parts":[[2022,9,22]],"date-time":"2022-09-22T18:00:10Z","timestamp":1663869610000},"page":"e0274821","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":8,"title":["Features of non-traumatic spinal cord infarction on MRI: Changes over time"],"prefix":"10.1371","volume":"17","author":[{"given":"Bo Ra","family":"Kim","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyung 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