{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T03:01:53Z","timestamp":1787022113377,"version":"build-2736575974"},"reference-count":31,"publisher":"Public Library of Science (PLoS)","issue":"12","license":[{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Cardiac rehabilitation improves prognosis and symptoms in cardiac patients. In 2020, due to the COVID-19 pandemic, cardiac rehabilitation services were temporarily suspended between April and August. We aimed to investigate the effect of cardiac rehabilitation suspension during the COVID-19 pandemic on patients\u2019 exercise capacity and metabolic parameters.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec002\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Included were patients undergoing cardiac rehabilitation following hospital admission for ACS. Exercise capacity, weight and body fat percentage were compared between baseline, pre- and post-lockdown visits.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec003\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 281 patients participated in the cardiac rehabilitation program prior to its suspension. Of them, only 198 (70%) patients returned to the program on its renewal and were included in the analysis. Exercise capacity improved significantly in the pre-lockdown stress test compared to baseline. However, there was a significant decrease in exercise capacity in the post compared to pre-lockdown test (8.1\u00b16.3 and 7.1\u00b12.1 METs in pre- and post-lockdown measurements, respectively, p&lt;0.001). Of the 99 (50%) of patients that demonstrated at least 10% improvement in exercise capacity in the pre-lockdown test, 48(48.5%) patients returned to their baseline values in the post-lockdown test. Post-lockdown assessment demonstrated a significant weight gain (80.3 and 81.1kg, in pre- and post-lockdown measurements, respectively, p&lt;0.001) as well as an increase in visceral fat level and body fat percentage.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec004\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Cardiac rehabilitation suspension for 4 months during COVID-19 pandemic caused a significant reduction in exercise capacity and increased weight and body fat percent. These findings highlight the importance of remote cardiac rehabilitation services that can continue uninterrupted in times of pandemic.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1371\/journal.pone.0276106","type":"journal-article","created":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T14:56:58Z","timestamp":1669906618000},"page":"e0276106","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":9,"title":["The impact of COVID-19 pandemic on cardiac rehabilitation of patients following acute coronary syndrome"],"prefix":"10.1371","volume":"17","author":[{"given":"Feras","family":"Haskiah","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rana","family":"Jbara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saar","family":"Minha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abid","family":"Assali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaron","family":"Sela","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3394-2032","authenticated-orcid":true,"given":"David","family":"Pereg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2022,12,1]]},"reference":[{"issue":"7","key":"pone.0276106.ref001","first-page":"CD001800","article-title":"Exercise-based cardiac rehabilitation for coronary heart disease","author":"BS Heran","year":"2011","journal-title":"Cochrane Database Syst Rev"},{"issue":"1","key":"pone.0276106.ref002","first-page":"CD001800","article-title":"Exercise-based cardiac rehabilitation for coronary heart disease","volume":"2016","author":"RS Taylor","year":"2016","journal-title":"Cochrane Database Syst Rev"},{"issue":"1","key":"pone.0276106.ref003","first-page":"CD003331","article-title":"Exercise-based cardiac rehabilitation for adults with heart failure","volume":"1","author":"L Long","year":"2019","journal-title":"Cochrane Database Syst Rev"},{"issue":"1","key":"pone.0276106.ref004","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1093\/eurheartj\/ehaa605","article-title":"2020 ESC Guidelines on sports cardiology and exercise in patients with cardiovascular disease: The Task Force on sports cardiology and exercise in patients with cardiovascular disease of the European Society of Cardiology (ESC)","volume":"42","author":"A Pelliccia","year":"2021","journal-title":"Eur Heart J"},{"issue":"2","key":"pone.0276106.ref005","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1177\/2047487319893035","article-title":"Update on cardiovascular prevention in clinical practice: A position paper of the European Association of Preventive Cardiology of the European Society of Cardiology","volume":"27","author":"MF Piepoli","year":"2020","journal-title":"Eur J Prev Cardiol"},{"issue":"2","key":"pone.0276106.ref006","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1093\/eurheartj\/ehx393","article-title":"2017 ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation: The Task Force for the management of acute myocardial infarction in patients presenting with ST-segment elevation of the European Society of Cardiology (ESC)","volume":"39","author":"B Ibanez","year":"2018","journal-title":"Eur Heart J"},{"issue":"14","key":"pone.0276106.ref007","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1093\/eurheartj\/ehaa575","article-title":"2020 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation","volume":"42","author":"JP Collet","year":"2021","journal-title":"Eur Heart J"},{"issue":"16","key":"pone.0276106.ref008","doi-asserted-by":"crossref","first-page":"1775","DOI":"10.1177\/2047487320912625","article-title":"Quantifying the impact of delayed delivery of cardiac rehabilitation on patients\u2019 health","volume":"27","author":"S Hinde","year":"2020","journal-title":"Eur J Prev Cardiol"},{"issue":"4","key":"pone.0276106.ref009","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1007\/s40520-020-01589-x","article-title":"Early cardiac rehabilitation: could it improve functional outcomes and reduce length of stay and sanitary costs in patients aged 75 years or older? 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