{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T15:49:45Z","timestamp":1792684185412,"version":"4.5.0"},"reference-count":48,"publisher":"Public Library of Science (PLoS)","issue":"10","license":[{"start":{"date-parts":[[2022,10,20]],"date-time":"2022-10-20T00:00:00Z","timestamp":1666224000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\">\n<jats:title>Objectives<\/jats:title>\n<jats:p>We sought to examine readmission rates and predictors of hospital readmission following TAVR in patients with ESRD.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec002\">\n<jats:title>Background<\/jats:title>\n<jats:p>End-stage renal disease (ESRD) is associated with poor outcomes following transcatheter aortic valve replacement (TAVR).<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec003\">\n<jats:title>Methods<\/jats:title>\n<jats:p>We assessed index hospitalizations for TAVR from the National Readmissions Database from 2017 to 2018 and used propensity scores to match those with and without ESRD. We compared 90-day readmission for any cause or cardiovascular cause. Length of stay (LOS), mortality, and cost were assessed for index hospitalizations and 90-day readmissions. Multivariable logistic regression was performed to identify predictors of 90-day readmission.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec004\">\n<jats:title>Results<\/jats:title>\n<jats:p>We identified 49,172 index hospitalizations for TAVR, including 1,219 patients with ESRD (2.5%). Patient with ESRD had higher rates of all-cause readmission (34.4% vs. 19.2%, HR 1.96, 95% CI 1.68\u20132.30, p&lt;0.001) and cardiovascular readmission (13.2% vs. 7.7%, HR 1.85, 95% CI 1.44\u20132.38, p&lt;0.001) at 90 days. During index hospitalization, patients with ESRD had longer length of stay (mean difference 1.9 days), increased hospital cost (mean difference $42,915), and increased in-hospital mortality (2.6% vs. 0.9%). Among those readmitted within 90 days, patients with ESRD had longer LOS and increased hospital charge, but similar in-hospital mortality. Diabetes (OR 1.86, 95% CI 1.31\u20132.64) and chronic pulmonary disease (OR 1.51, 95% CI 1.04\u20132.18) were independently associated with higher odds of 90-day readmission in patients with ESRD.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec005\">\n<jats:title>Conclusion<\/jats:title>\n<jats:p>Patients with ESRD undergoing TAVR have higher mortality and increased cost associated with their index hospitalization and are at increased risk of readmission within 90 days following TAVR.<\/jats:p>\n<\/jats:sec>","DOI":"10.1371\/journal.pone.0276394","type":"journal-article","created":{"date-parts":[[2022,10,20]],"date-time":"2022-10-20T18:23:53Z","timestamp":1666290233000},"page":"e0276394","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":7,"title":["Readmission rates and risk factors for readmission after transcatheter aortic valve replacement in patients with end-stage renal disease"],"prefix":"10.1371","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1486-7452","authenticated-orcid":true,"given":"Dae Yong","family":"Park","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1971-1094","authenticated-orcid":true,"given":"Seokyung","family":"An","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan M.","family":"Hanna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen Y.","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana 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Al","family":"Damluji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5745-1636","authenticated-orcid":true,"given":"Michael G.","family":"Nanna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2022,10,20]]},"reference":[{"issue":"3","key":"pone.0276394.ref001","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1111\/sdi.12582","article-title":"Aortic Stenosis in Dialysis Patients","volume":"30","author":"Y Ahmad","year":"2017","journal-title":"Semin Dial"},{"issue":"7","key":"pone.0276394.ref002","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.116.004961","article-title":"Severe Aortic Stenosis in Dialysis Patients","volume":"6","author":"Y Kawase","year":"2017","journal-title":"J Am Heart 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