{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T02:04:49Z","timestamp":1788228289494,"version":"build-2803163510"},"reference-count":24,"publisher":"Public Library of Science (PLoS)","issue":"10","license":[{"start":{"date-parts":[[2022,10,21]],"date-time":"2022-10-21T00:00:00Z","timestamp":1666310400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004085","name":"Ministry of Education, Science and Technology","doi-asserted-by":"publisher","award":["NRF-2020R1F1A1055076"],"award-info":[{"award-number":["NRF-2020R1F1A1055076"]}],"id":[{"id":"10.13039\/501100004085","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\">\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Previous studies have shown that, thread carpal tunnel release (TCTR), an ultrasound-guided transverse carpal ligament (TCL) transection procedure through needle and thread, to be a safe and effective technique for carpal tunnel release, compared to an open and endoscopic technique. We developed a newly improved thread (Smartwire-01, 0.27mm in diameter, Korea). This pilot study was performed to propose the effectiveness of TCTR with Smartwire-01 compared to the commercial thread in clinical settings.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec002\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A total of 22 TCTR procedures have been performed on 19 patients by one physiatrist during a 42-month period. The diagnosis of carpal tunnel syndrome was based on standard clinical criteria including electromyography (EMG). Patients were divided into two groups, one dissected with commercial thread and the other with Smartwire-01. The technique was standardized by keeping the entry point at the middle of the palm and the exit point at just medial to the palmaris longus tendon. The Numeric Rating Scale and Boston Carpal Tunnel Syndrome Questionnaire (BCTQ) were used to assess monthly outcomes for 6 months following the procedure. The Wilcoxon signed rank test and the Mann-Whitney-U test were performed to analyze the above variables in the two groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec003\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>There was no definite evidence that the two groups have significant differences for any of the surveyed variables. The TCTR procedure with our newly developed thread also had significant improvements for all variables, showing its effectiveness in both pain and functional ability. The NRS and BCTQ severity and functional scales showed significant decreases just after the dissection and progressive improvement during each monthly follow-up of our study until the last assessment at 6 months.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec004\">\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The study suggests that, our newly developed thread is as safe and effective as the commercial thread in TCTR, we therefore recommend a randomize controlled trial with above methodology.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1371\/journal.pone.0276630","type":"journal-article","created":{"date-parts":[[2022,10,21]],"date-time":"2022-10-21T13:29:22Z","timestamp":1666358962000},"page":"e0276630","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":11,"title":["A clinical study of thread carpal tunnel release with a newly developed thread: A retrospective pilot study"],"prefix":"10.1371","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5723-691X","authenticated-orcid":true,"given":"Jisoo","family":"Park","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"In Jong","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7773-6329","authenticated-orcid":true,"given":"Hae-yeon","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong jin","family":"Heo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4217-3228","authenticated-orcid":true,"given":"Jae Min","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2022,10,21]]},"reference":[{"issue":"11","key":"pone.0276630.ref001","doi-asserted-by":"crossref","first-page":"1431","DOI":"10.1212\/WNL.56.11.1431","article-title":"Carpal tunnel syndrome: complex issues with a \"simple\" condition","volume":"56","author":"RK Olney","year":"2001","journal-title":"Neurology"},{"issue":"12","key":"pone.0276630.ref002","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1016\/S1474-4422(16)30231-9","article-title":"Carpal tunnel syndrome: clinical features, diagnosis, and management","volume":"15","author":"L Padua","year":"2016","journal-title":"Lancet Neurol"},{"issue":"12","key":"pone.0276630.ref003","doi-asserted-by":"crossref","first-page":"1392","DOI":"10.1002\/mus.880161220","article-title":"Literature review of the usefulness of nerve conduction studies and electromyography for the evaluation of patients with carpal tunnel syndrome. AAEM Quality Assurance Committee","volume":"16","author":"CK Jablecki","year":"1993","journal-title":"Muscle Nerve"},{"issue":"8","key":"pone.0276630.ref004","doi-asserted-by":"crossref","first-page":"1654","DOI":"10.1212\/WNL.53.8.1654","article-title":"Multiperspective assessment of carpal tunnel syndrome: a multicenter study. Italian CTS Study Group","volume":"53","author":"L Padua","year":"1999","journal-title":"Neurology"},{"issue":"12","key":"pone.0276630.ref005","doi-asserted-by":"crossref","first-page":"858","DOI":"10.7326\/0003-4819-159-12-201312170-00020","article-title":"Methylprednisolone injections for the carpal tunnel syndrome","volume":"159","author":"I Atroshi","year":"2013","journal-title":"Ann Intern Med"},{"issue":"3","key":"pone.0276630.ref006","doi-asserted-by":"crossref","first-page":"1120","DOI":"10.1007\/s11999-014-3835-z","article-title":"Open versus endoscopic carpal tunnel release: a meta-analysis of randomized controlled trials","volume":"473","author":"ET Sayegh","year":"2015","journal-title":"Clin Orthop Relat Res"},{"issue":"7","key":"pone.0276630.ref007","doi-asserted-by":"crossref","first-page":"1479","DOI":"10.1016\/j.clinph.2013.11.010","article-title":"Local injection versus surgery in carpal tunnel syndrome: neurophysiologic outcomes of a randomized clinical trial","volume":"125","author":"JL Andreu","year":"2014","journal-title":"Clin Neurophysiol"},{"key":"pone.0276630.ref008","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1186\/1749-799X-6-17","article-title":"Is surgical intervention more effective than non-surgical treatment for carpal tunnel syndrome? A systematic review","volume":"6","author":"Q Shi","year":"2011","journal-title":"J Orthop Surg Res"},{"issue":"10","key":"pone.0276630.ref009","doi-asserted-by":"crossref","first-page":"e351","DOI":"10.1016\/j.jhsa.2016.07.098","article-title":"A Cadaveric Study for the Improvement of Thread Carpal Tunnel Release","volume":"41","author":"D Guo","year":"2016","journal-title":"J Hand Surg Am"},{"issue":"1","key":"pone.0276630.ref010","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1177\/1558944719842199","article-title":"A Controlled Trial Evaluating the Safety and Effectiveness of Ultrasound-Guided Looped Thread Carpal Tunnel Release","volume":"16","author":"RS Burnham","year":"2021","journal-title":"Hand (N Y)"},{"key":"pone.0276630.ref011","article-title":"Return to work following ultrasound guided thread carpal tunnel release versus open carpal tunnel release: a comparative study","author":"DB Asserson","year":"2021","journal-title":"J Hand Surg Eur Vol"},{"issue":"5","key":"pone.0276630.ref012","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1177\/1558944716668831","article-title":"A Clinical Study of the Modified Thread Carpal Tunnel Release","volume":"12","author":"D Guo","year":"2017","journal-title":"Hand (N Y)"},{"issue":"1","key":"pone.0276630.ref013","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1007\/s11552-014-9656-4","article-title":"A non-scalpel technique for minimally invasive surgery: percutaneously looped thread transection of the transverse carpal ligament","volume":"10","author":"D Guo","year":"2015","journal-title":"Hand (N Y)"},{"issue":"1","key":"pone.0276630.ref014","doi-asserted-by":"crossref","first-page":"131","DOI":"10.7863\/jum.2013.32.1.131","article-title":"Ultra-minimally invasive sonographically guided carpal tunnel release: anatomic study of a new technique","volume":"32","author":"JM Rojo-Manaute","year":"2013","journal-title":"J Ultrasound Med"},{"issue":"11","key":"pone.0276630.ref015","doi-asserted-by":"crossref","first-page":"1585","DOI":"10.2106\/00004623-199311000-00002","article-title":"A self-administered questionnaire for the assessment of severity of symptoms and functional status in carpal tunnel syndrome","volume":"75","author":"DW Levine","year":"1993","journal-title":"J Bone Joint Surg Am"},{"issue":"2","key":"pone.0276630.ref016","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/S0749-0712(01)00003-8","article-title":"Practical anatomy of the carpal tunnel","volume":"18","author":"MB Rotman","year":"2002","journal-title":"Hand Clin"},{"issue":"1","key":"pone.0276630.ref017","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/S0266-7681(99)90009-8","article-title":"Does endoscopic carpal tunnel release have a higher rate of complications than open carpal tunnel release? An analysis of published series","volume":"24","author":"ME Boeckstyns","year":"1999","journal-title":"J Hand Surg Br"},{"issue":"2","key":"pone.0276630.ref018","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1016\/j.ocl.2015.09.015","article-title":"Complications of Carpal Tunnel Release","volume":"47","author":"JW Karl","year":"2016","journal-title":"Orthop Clin North Am"},{"issue":"7","key":"pone.0276630.ref019","doi-asserted-by":"crossref","first-page":"1830","DOI":"10.1097\/00006534-200106000-00031","article-title":"Secondary carpal tunnel surgery","volume":"107","author":"TH Tung","year":"2001","journal-title":"Plast Reconstr Surg"},{"issue":"2","key":"pone.0276630.ref020","doi-asserted-by":"crossref","first-page":"248","DOI":"10.5603\/FM.a2020.0049","article-title":"The anatomical landmarks effective in the localisation of the median nerve during orthopaedic procedures","volume":"80","author":"E Mizia","year":"2021","journal-title":"Folia Morphol (Warsz)"},{"issue":"1","key":"pone.0276630.ref021","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1177\/1558944718787330","article-title":"Accuracy of Carpal Tunnel Injection: A Prospective Evaluation of 756 Patients","volume":"15","author":"DP Green","year":"2020","journal-title":"Hand (N Y)"},{"issue":"7","key":"pone.0276630.ref022","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1097\/PHM.0000000000000652","article-title":"Evaluation of the Effectiveness and Safety of Ultrasound-Guided Percutaneous Carpal Tunnel Release: A Cadaveric Study","volume":"96","author":"R Burnham","year":"2017","journal-title":"Am J Phys Med Rehabil"},{"issue":"4","key":"pone.0276630.ref023","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1016\/j.ocl.2012.07.013","article-title":"Evaluation and treatment of failed carpal tunnel release","volume":"43","author":"V Neuhaus","year":"2012","journal-title":"Orthop Clin North Am"},{"issue":"2","key":"pone.0276630.ref024","doi-asserted-by":"crossref","first-page":"175","DOI":"10.3758\/BF03193146","article-title":"G*Power 3: a flexible statistical power analysis program for the social, behavioral, and biomedical sciences","volume":"39","author":"F Faul","year":"2007","journal-title":"Behav Res Methods"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0276630","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,10,21]],"date-time":"2022-10-21T13:29:55Z","timestamp":1666358995000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0276630"}},"subtitle":[],"editor":[{"given":"Ibrahim Umar","family":"Garzali","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2022,10,21]]},"references-count":24,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2022,10,21]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0276630","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,10,21]]}}}