{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T04:18:42Z","timestamp":1747196322589,"version":"3.40.5"},"reference-count":19,"publisher":"Public Library of Science (PLoS)","issue":"11","license":[{"start":{"date-parts":[[2022,11,30]],"date-time":"2022-11-30T00:00:00Z","timestamp":1669766400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:p>Over the first half of March 2021, the majority of European governments suspended Astrazeneca\u2019s Vaxzevria vaccine as a precaution following media reports of rare blood clots. We analyse the impact of the European Medicines Agency\u2019s (EMA) March 18th statement assuring the public of the safety of Vaxzevria and the immediate reinstatement of the vaccine by most countries on respondents\u2019 intention to get vaccinated. By relying on survey data collected in Luxembourg and neighbouring areas between early March and mid-April, we observe that the willingness to be vaccinated was severely declining in the days preceding the EMA statement. We implement a regression discontinuity design exploiting the time at which respondents completed the survey and find that the vaccine reinstatement substantially restored vaccination intentions.<\/jats:p>","DOI":"10.1371\/journal.pone.0277554","type":"journal-article","created":{"date-parts":[[2022,11,30]],"date-time":"2022-11-30T18:34:16Z","timestamp":1669833256000},"page":"e0277554","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":0,"title":["Can a supranational medicines agency restore trust after vaccine suspensions? The case of Vaxzevria"],"prefix":"10.1371","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2389-2905","authenticated-orcid":true,"given":"Andrea","family":"Albanese","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5502-4358","authenticated-orcid":true,"given":"Francesco","family":"Fallucchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bertrand","family":"Verheyden","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2022,11,30]]},"reference":[{"key":"pone.0277554.ref001","doi-asserted-by":"crossref","first-page":"17","DOI":"10.3390\/vaccines9010017","article-title":"Social patterning and stability of intention to accept a COVID-19 vaccine in Scotland: Will those most at risk accept a vaccine?","volume":"9","author":"L 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Goldstein","year":"2015","journal-title":"Vaccine"},{"key":"pone.0277554.ref013","article-title":"Online Social Endorsement and COVID-19 Vaccine Hesitancy in the United Kingdom","volume":"7","author":"A Chadwick","year":"2021","journal-title":"Social Media and Society"},{"key":"pone.0277554.ref014","first-page":"1","author":"N Puri","year":"2020","journal-title":"Social media and vaccine hesitancy: new updates for the era of COVID-19 and globalized infectious diseases Human Vaccines Immunotherapeutics"},{"key":"pone.0277554.ref015","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41467-020-20226-9","article-title":"sychological characteristics associated with COVID-19 vaccine hesitancy and resistance in Ireland and the United Kingdom","volume":"12","author":"J Murphy","year":"2021","journal-title":"Nature Communications"},{"key":"pone.0277554.ref016","doi-asserted-by":"crossref","first-page":"2295","DOI":"10.3982\/ECTA11757","article-title":"Robust nonparametric 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