{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T07:01:08Z","timestamp":1790838068326,"version":"4.1.0"},"reference-count":20,"publisher":"Public Library of Science (PLoS)","issue":"7","license":[{"start":{"date-parts":[[2023,7,14]],"date-time":"2023-07-14T00:00:00Z","timestamp":1689292800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Roche India Healthcare Institute."}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\">\n                    <jats:title>Background and aim<\/jats:title>\n                    <jats:p>The Telangana cancer care program is a proactive, comprehensive initiative encompassing infrastructure development, human resource skilling and ensuring financial protection to those below poverty line. The broad aim of this exercise was to identify modalities to augment the Telangana State Cancer Control Plan to implement a sustainable comprehensive cancer care model for Telangana.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec002\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted in-depth interviews of stakeholders (17 patients and 25 health care providers) to identify barriers and challenges to access existing cancer care system in Telangana; calculated the magnitude of cancer and commensurate workload (in terms of visits to tertiary cancer care system for cancer management and human and equipment requirement) for the next 15 years (from 2022 to 2037). Using the anecdotal evidence and information from stakeholders\u2019 interviews, we developed patient-journey funnels for oral, breast, and cervical cancer patients to highlight patient leakages at various levels of cancer care.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec003\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We estimated a 13%, 28%, and 44.7% increase in the number of new cancer cases and the resultant workload (number of visits to health care centre, chemotherapy sessions, radiotherapy sessions, surgeries, specialized human resources and equipment), for the year 2027, 2032, and 2037, respectively, compared to the year 2022. The stakeholders mentioned \u2018delayed access\u2019 to healthcare system as the main reason for the poor prognosis of patients. The common reasons cited for \u2018delayed access\u2019 were: poor cancer-literacy including prevailing myths and misconception, financial barriers, and rural residence. The patient journey funnel for cancer care revealed a major leakage from \u2018screened-positive\u2019 to \u2018diagnosis confirmation\u2019 step. The estimated patient leakage varied from ~70% to 90% from \u2018screened-positive\u2019 till \u2018treatment completion\u2019.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec004\">\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In this study, we anticipated a steady increase in the number of new cancers cases and resultant workload for the state of Telangana from the year 2022 to 2037. This may further be accompanied with limited access or utilization of cancer care system. To manage this public health issue, government should take appropriate measures to improve cancer literacy at the community level as well as increase human resources and necessary equipment.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1371\/journal.pone.0278357","type":"journal-article","created":{"date-parts":[[2023,7,14]],"date-time":"2023-07-14T13:42:45Z","timestamp":1689342165000},"page":"e0278357","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":10,"title":["Projected cancer burden, challenges, and barriers to cancer prevention and control activities in the state of Telangana"],"prefix":"10.1371","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7874-9191","authenticated-orcid":true,"given":"Hemant","family":"Mahajan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neha","family":"Reddy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1845-0021","authenticated-orcid":true,"given":"N. G. Marina","family":"Devi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6336-2274","authenticated-orcid":true,"given":"Usha Rani","family":"Poli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Jayaram","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shailaja","family":"Tetali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5695-866X","authenticated-orcid":true,"given":"G. V. S.","family":"Murthy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"on behalf of the Telangana Cancer Control Study Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2023,7,14]]},"reference":[{"key":"pone.0278357.ref001","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1016\/S1470-2045(18)30447-9","article-title":"The burden of cancers and their variations across the states of india: The global burden of disease study 1990\u20132016","volume":"19","year":"2018","journal-title":"Lancet Oncology"},{"key":"pone.0278357.ref002","author":"National centre for disease informatics and research, bengaluru","year":"2020","journal-title":"Report of national cancer registry programme (icmr-ncdir), bengaluru, india"},{"key":"pone.0278357.ref003","doi-asserted-by":"crossref","first-page":"2437","DOI":"10.1016\/S0140-6736(17)32804-0","article-title":"Nations within a nation: Variations in epidemiological transition across the states of india, 1990\u20132016 in the global burden of disease study","volume":"390","author":"L Dandona","year":"2017","journal-title":"The Lancet"},{"key":"pone.0278357.ref004","doi-asserted-by":"crossref","first-page":"353","DOI":"10.4103\/0019-509X.200682","article-title":"Epidemiological and survival analysis of triple-negative breast cancer cases in a retrospective multicenter study","volume":"53","author":"R Sarin","year":"2016","journal-title":"Indian Journal of Cancer"},{"key":"pone.0278357.ref005","doi-asserted-by":"crossref","first-page":"e119","DOI":"10.1016\/S1470-2045(13)70547-3","article-title":"Evidence-informed frameworks for cost-effective cancer care and prevention in low, middle, and high-income countries","volume":"15","author":"K Chalkidou","year":"2014","journal-title":"Lancet Oncology."},{"key":"pone.0278357.ref006","doi-asserted-by":"crossref","first-page":"e113","DOI":"10.1016\/S1470-2045(18)30003-2","article-title":"Population-based cancer screening programmes in low-income and middle-income countries: Regional consultation of the international cancer screening network in india","volume":"19","author":"S Sivaram","year":"2018","journal-title":"Lancet Oncology"},{"key":"pone.0278357.ref007","author":"Centers for disease control and prevention","year":"2016","journal-title":"Gats 2 global adult tobacco survey gats objectives gats 2 highlights"},{"key":"pone.0278357.ref008","author":"Icmr-national center for disease informatics and research","year":"2021","journal-title":"Profile of cancer and related factors- telangana"},{"key":"pone.0278357.ref009","unstructured":"Population projections for india and states 2011\u20132036. 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[accessed on: 2022 aug 28]."},{"key":"pone.0278357.ref018","author":"Ministry of statistics and programme implementation national statistical office","year":"2018","journal-title":"Key indicators of social consumption in india: Health nss 75th round july 2017"},{"key":"pone.0278357.ref019","doi-asserted-by":"crossref","first-page":"3639","DOI":"10.7314\/APJCP.2015.16.9.3639","article-title":"Using implementation science to advance cancer prevention in india","volume":"16","author":"S Krishnan","year":"2015","journal-title":"Asian Pacific journal of cancer prevention"},{"key":"pone.0278357.ref020","unstructured":"Government of telangana and tata trusts signed mou to provide state-wide cancer care: Press releases; [accessed on: 2021 may 11]."}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0278357","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,14]],"date-time":"2023-07-14T13:43:12Z","timestamp":1689342192000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0278357"}},"subtitle":[],"editor":[{"given":"Rajiv","family":"Janardhanan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2023,7,14]]},"references-count":20,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2023,7,14]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0278357","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/2022.11.16.22282378","asserted-by":"object"}]},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,7,14]]}}}