{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T03:01:55Z","timestamp":1787022115270,"version":"build-2736575974"},"reference-count":49,"publisher":"Public Library of Science (PLoS)","issue":"12","license":[{"start":{"date-parts":[[2022,12,16]],"date-time":"2022-12-16T00:00:00Z","timestamp":1671148800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"King\u2019s Medical Research Trust"},{"name":"King\u2019s Medical Research Trust"},{"name":"King\u2019s Medical Research Trust"},{"name":"The Malcolm Coptcoat Trust"},{"name":"The Malcolm Coptcoat Trust"},{"name":"The Malcolm Coptcoat Trust"},{"name":"The Malcolm Coptcoat Trust"},{"DOI":"10.13039\/501100000265","name":"Medical Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000265","name":"Medical Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000265","name":"Medical Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000265","name":"Medical Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100016386","name":"Vattikuti Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100016386","id-type":"DOI","asserted-by":"publisher"}]},{"name":"The Urology Foundation"},{"DOI":"10.13039\/501100000380","name":"Guy\u2019s and St Thomas\u2019 Charity","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000380","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000872","name":"Pelican Cancer Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000872","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100019418","name":"NIHR Maudsley Biomedical Research Centre","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100019418","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000272","name":"National Institute for Health and Care Research","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100000272","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\">\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Quality of life in prostate cancer survivorship is becoming increasingly important, with mental and social wellbeing recognised as key components. However, limited global evaluation of psychosocial challenges experienced after treatment exists. Therefore, we aimed to explore the lived experiences of men who underwent radical treatment, and its psychosocial impact.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec002\">\n                    <jats:title>Material and methods<\/jats:title>\n                    <jats:p>This qualitative study was conducted using 19 men who had undergone radical treatment (prostatectomy or radiotherapy) for their cancer. Semi-structured interviews were conducted exploring lived experiences of men after treatment. A Structured thematic analysis of collected data was undertaken, with an inductive co-construction of themes through the lens of the biopsychosocial model. Themes generated were considered within a psychological, social, and physical wellbeing framework.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec003\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>An initial knowledge gap meant mental wellbeing was strongly impacted initially leading to a \u2018Diagnostic Blow and the Search for Clarity\u2019. Doubt over individuals\u2019 future resulted in \u2018An Uncertain Future\u2019 in many men. Once treatment was completed a \u2018Reflective journey\u2019 began, with men considering their outcomes and decisions made. Social wellbeing was also impacted with many identifying the \u2018Emotional Repercussions\u2019 on their relationships and the impact their diagnosis had on their partner and family. Many subsequently sought to increase their support through \u2018The Social Network and Advocacy\u2019, while physical changes led to an increased need for \u2018Social Planning\u2019. Finally, physical wellbeing was highlighted by a continual acknowledgement of the \u2018Natural process of ageing\u2019 leading to a reluctancy to seek help, whilst simultaneously attempting to improve existing health via \u2018The Health Kick\u2019.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec004\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Radical treatments have a considerable impact on mental and social wellbeing of individuals. Anxiety after diagnosis and significant uncertainty over individual futures exist, with physical complications of treatment leading to social repercussions. Future research should aim to identify forms of support to improve quality of life of these men.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1371\/journal.pone.0279250","type":"journal-article","created":{"date-parts":[[2022,12,16]],"date-time":"2022-12-16T13:24:57Z","timestamp":1671197097000},"page":"e0279250","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":19,"title":["Undergoing radical treatment for prostate cancer and its impact on wellbeing: A qualitative study exploring men\u2019s experiences"],"prefix":"10.1371","volume":"17","author":[{"given":"Neel","family":"Vyas","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2073-922X","authenticated-orcid":true,"given":"Oliver","family":"Brunckhorst","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louis","family":"Fox","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mieke","family":"Van 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