{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T12:43:33Z","timestamp":1791549813666,"version":"4.3.4"},"reference-count":69,"publisher":"Public Library of Science (PLoS)","issue":"8","license":[{"start":{"date-parts":[[2023,8,10]],"date-time":"2023-08-10T00:00:00Z","timestamp":1691625600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Monkeypox (mpox), re-emerging zoonotic infectious disease, is striking the world with serious public health concerns, especially in non-endemic countries. The public\u2019s knowledge and attitude towards the monkeypox virus (MPXV) influence their adherence to preventive strategies. Therefore, we aimed to assess the public\u2019s knowledge, attitudes, and perceptions (KAP) of MPXV in Pakistan.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec002\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      We collected data for this cross-sectional study from 1040 participants via online self-reported questionnaire from July 5\n                      <jats:sup>th<\/jats:sup>\n                      , 2022, to August 1\n                      <jats:sup>st<\/jats:sup>\n                      , 2022. The questionnaire consisted of a total of 29 items in four sections, assessing socio-demographics, knowledge, attitudes, and practices regarding MPXV. The data were analyzed using IBM SPSS V.25, and factors associated with MPXV knowledge, attitude, and practices were identified by using logistic regression analyses.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec003\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 1040 participants were included. 61.4% were male, and 57.2% had graduation level education. Only 34.4% had good knowledge about MPXV, and 30% knew the effectiveness of the smallpox vaccine against MPXV. 41.7% had a positive attitude, 48.6% agreed that it is a fatal disease, and 44.6% were in favour of banning travel from endemic to non-endemic regions. 57.7% had good practices, and 69.9% would use protective measures if MPXV became an epidemic. Binary logistic regression analysis revealed that gender and education significantly impacted knowledge (p&lt;0.05). While monthly income status had a significant impact on attitudes (p&lt;0.05). The practices were positively correlated with gender and education (p&lt;0.05).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec004\">\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The majority of study participants had inadequate levels of knowledge, and attitudes regarding MPXV. To prevent the emergence and spread of MPXV in Pakistan, a comprehensive strategic framework for public health education must be established and implemented.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1371\/journal.pone.0279952","type":"journal-article","created":{"date-parts":[[2023,8,10]],"date-time":"2023-08-10T13:45:46Z","timestamp":1691675146000},"page":"e0279952","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":19,"title":["Socio-demographic determinants of Monkeypox virus preventive behavior: A cross-sectional study in Pakistan"],"prefix":"10.1371","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2647-6723","authenticated-orcid":true,"given":"Hashaam","family":"Jamil","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9516-8214","authenticated-orcid":true,"given":"Muhammad","family":"Idrees","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kashmala","family":"Idrees","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8480-2710","authenticated-orcid":true,"given":"Waleed","family":"Tariq","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qudsia","family":"Sayyeda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6705-2030","authenticated-orcid":true,"given":"Muhammad Sohaib","family":"Asghar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad Junaid","family":"Tahir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samra","family":"Akram","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7819-6910","authenticated-orcid":true,"given":"Kaleem","family":"Ullah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8964-1853","authenticated-orcid":true,"given":"Ali","family":"Ahmed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aroop","family":"Mohanty","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bijaya Kumar","family":"Padhi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2695-8714","authenticated-orcid":true,"given":"Ranjit","family":"Sah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2023,8,10]]},"reference":[{"issue":"7","key":"pone.0279952.ref001","first-page":"e26531","article-title":"Monkeypox: A Comprehensive Review of Transmission, Pathogenesis, and Manifestation","volume":"14","author":"J Kaler","year":"2022","journal-title":"Cureus"},{"issue":"10","key":"pone.0279952.ref002","doi-asserted-by":"crossref","first-page":"1","DOI":"10.14295\/bjs.v1i10.179","article-title":"Monkeypox cases in Brazil, a possible pandemic","volume":"1","author":"ACP de Menezes Filho","year":"2022","journal-title":"Brazilian Journal of Science"},{"key":"pone.0279952.ref003","volume-title":"StatPearls","author":"M Moore","year":"2021"},{"issue":"11","key":"pone.0279952.ref004","doi-asserted-by":"crossref","DOI":"10.3390\/v12111257","article-title":"Monkeypox Virus in Nigeria: Infection Biology, Epidemiology, and Evolution","volume":"12","author":"E Alakunle","year":"2020","journal-title":"Viruses"},{"issue":"4","key":"pone.0279952.ref005","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1016\/j.idc.2019.03.001","article-title":"Human Monkeypox: Epidemiologic and Clinical Characteristics, Diagnosis, and Prevention","volume":"33","author":"E Petersen","year":"2019","journal-title":"Infectious disease clinics of North America"},{"issue":"8","key":"pone.0279952.ref006","article-title":"Monkeypox and Its Possible Sexual Transmission: Where Are We Now with Its Evidence?","volume":"11","author":"R Sah","year":"2022","journal-title":"Pathogens"},{"issue":"7","key":"pone.0279952.ref007","doi-asserted-by":"crossref","DOI":"10.3390\/pathogens11070713","article-title":"Monkeypox: Another Sexually 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