{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T06:39:42Z","timestamp":1768459182081,"version":"3.49.0"},"reference-count":31,"publisher":"Public Library of Science (PLoS)","issue":"1","license":[{"start":{"date-parts":[[2023,1,3]],"date-time":"2023-01-03T00:00:00Z","timestamp":1672704000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100007553","name":"Aidsfonds","doi-asserted-by":"publisher","award":["P-42702"],"award-info":[{"award-number":["P-42702"]}],"id":[{"id":"10.13039\/100007553","id-type":"DOI","asserted-by":"publisher"}]},{"name":"H-TEAM"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\">\n<jats:title>Background<\/jats:title>\n<jats:p>HIV testing among patients with malignant lymphoma (PWML) is variably implemented. We evaluated HIV testing among PWML, and mapped factors influencing hematologists\u2019 testing behavior.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec002\">\n<jats:title>Materials<\/jats:title>\n<jats:p>We conducted a mixed-methods study assessing HIV testing among PWML, factors influencing HIV testing and opportunities for improvement in five hospitals in the region of Amsterdam, the Netherlands. The proportion of PWML tested for HIV within 3 months before or after lymphoma diagnosis and percentage positive were assessed from January 2015 through June 2020. Questionnaires on intention, behavior and psychosocial determinants for HIV testing were conducted among hematologists. Through twelve semi-structured interviews among hematologists and authors of hematology guidelines, we further explored influencing factors and opportunities for improvement.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec003\">\n<jats:title>Findings<\/jats:title>\n<jats:p>Overall, 1,612 PWML were included for analysis, including 976 patients newly diagnosed and 636 patients who were referred or with progressive\/relapsed lymphoma. Seventy percent (678\/976) of patients newly diagnosed and 54% (343\/636) of patients with known lymphoma were tested for HIV. Overall, 7\/1,021 (0.7%) PWML tested HIV positive, exceeding the 0.1% cost-effectiveness threshold. Questionnaires were completed by 40\/77 invited hematologists, and 85% reported intention to test PWML for HIV. In the interviews, hematologists reported varying HIV testing strategies, including testing all PWML or only when lymphoma treatment is required. Recommendations for improved HIV testing included guideline adaptations, providing electronic reminders and monitoring and increasing awareness.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec004\">\n<jats:title>Conclusions<\/jats:title>\n<jats:p>Missed opportunities for HIV testing among PWML occurred and HIV test strategies varied among hematologists. Efforts to improve HIV testing among PWML should include a combination of approaches.<\/jats:p>\n<\/jats:sec>","DOI":"10.1371\/journal.pone.0279958","type":"journal-article","created":{"date-parts":[[2023,1,3]],"date-time":"2023-01-03T19:00:35Z","timestamp":1672772435000},"page":"e0279958","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":2,"title":["Mapping hematologists\u2019 HIV testing behavior among lymphoma patients\u2013A mixed-methods study"],"prefix":"10.1371","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0436-6782","authenticated-orcid":true,"given":"Saskia","family":"Bogers","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hanne","family":"Zimmermann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amie","family":"Ndong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Udi","family":"Davidovich","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marie Jos\u00e9","family":"Kersten","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Reiss","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maarten","family":"Schim van der Loeff","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suzanne","family":"Geerlings","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"on behalf of the HIV Transmission Elimination AMsterdam (H-TEAM) Consortium","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2023,1,3]]},"reference":[{"key":"pone.0279958.ref001","article-title":"Global progress report on HIV, viral hepatitis and sexually transmitted infections, 2021","author":"World Health Organization","year":"2021"},{"issue":"1","key":"pone.0279958.ref002","doi-asserted-by":"crossref","first-page":"e52845","DOI":"10.1371\/journal.pone.0052845","article-title":"Feasibility and effectiveness of indicator condition-guided testing for HIV: results from HIDES I (HIV indicator diseases across Europe study).","volume":"8","author":"AK Sullivan","year":"2013","journal-title":"PLoS One"},{"issue":"8","key":"pone.0279958.ref003","doi-asserted-by":"crossref","first-page":"e0220108","DOI":"10.1371\/journal.pone.0220108","article-title":"Improving the evidence for indicator condition guided HIV testing in Europe: Results from the HIDES II Study\u20142012\u20132015","volume":"14","author":"D Raben","year":"2019","journal-title":"PLoS One"},{"key":"pone.0279958.ref004","doi-asserted-by":"crossref","first-page":"333","DOI":"10.2147\/CLEP.S101288","article-title":"Five-year risk of HIV diagnosis subsequent to 147 hospital-based indicator diseases: a Danish nationwide population-based cohort study","volume":"8","author":"LH Omland","year":"2016","journal-title":"Clin Epidemiol"},{"key":"pone.0279958.ref005","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1186\/1471-2334-13-473","article-title":"The potential impact of routine testing of individuals with HIV indicator diseases in order to prevent late HIV diagnosis","volume":"13","author":"P Scognamiglio","year":"2013","journal-title":"BMC Infect Dis"},{"issue":"5","key":"pone.0279958.ref006","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1016\/j.healthpol.2018.03.007","article-title":"Cost-effectiveness of HIV screening in high-income countries: A systematic review.","volume":"122","author":"F Bert","year":"2018","journal-title":"Health Policy"},{"issue":"3","key":"pone.0279958.ref007","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1016\/j.amjmed.2004.07.055","article-title":"Routine human immunodeficiency virus testing: an economic evaluation of current guidelines","volume":"118","author":"RP Walensky","year":"2005","journal-title":"Am J Med"},{"issue":"10","key":"pone.0279958.ref008","doi-asserted-by":"crossref","first-page":"e13132","DOI":"10.1371\/journal.pone.0013132","article-title":"Routine HIV screening in France: clinical impact and cost-effectiveness","volume":"5","author":"Y Yazdanpanah","year":"2010","journal-title":"PLoS One"},{"key":"pone.0279958.ref009","unstructured":"HIV Indicator Conditions: Guidance for Implementing HIV Testing in Adults in Health Care Settings. 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