{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,18]],"date-time":"2026-04-18T08:14:16Z","timestamp":1776500056927,"version":"3.51.2"},"reference-count":38,"publisher":"Public Library of Science (PLoS)","issue":"1","license":[{"start":{"date-parts":[[2023,1,20]],"date-time":"2023-01-20T00:00:00Z","timestamp":1674172800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\">\n<jats:title>Background<\/jats:title>\n<jats:p>Female students in institutions of higher education are at higher risk of abortion and its consequences. There is no nationally representative data on induced abortion among students in higher education institutions in Ethiopia. Hence, this study aimed to estimate the pooled prevalence of induced abortion among female students in institutions of higher education in Ethiopia.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec002\">\n<jats:title>Methods<\/jats:title>\n<jats:p>This study used a systematic review and meta-analysis of studies conducted from January 1, 2010, to June 30, 2022, in Ethiopia. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were followed. PubMed, Cochrane Library, Hinari, Google Scholar, CINAHL, and Global Health electronic databases were searched. The analysis was performed using STATA 14 software. Heterogeneity and publication bias were assessed using I<jats:sup>2<\/jats:sup> statistics and Egger\u2019s test, respectively. Duval and Tweedie\u2019s \u2018trim and fill\u2019 method was also performed to adjust the pooled estimate. Forest plots were used to present the pooled prevalence with a 95% confidence interval (CI) of meta-analysis using the random effect model.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec003\">\n<jats:title>Results<\/jats:title>\n<jats:p>This systematic review and meta-analysis included a total of 10 studies and 4656 study participants. The pooled prevalence of induced abortion among female students in institutions of higher education in Ethiopia was 5.06% (95%CI: 2.16, 7.96). The rate of induced abortion was 51 per 1000 women.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec004\">\n<jats:title>Conclusions<\/jats:title>\n<jats:p>The pooled prevalence of induced abortion among female students in institutions of higher education in Ethiopia was high. Thus, concerned bodies should design and implement an effective strategy to realize friendly and non-judgmental family planning and comprehensive abortion care service to curb the problem.<\/jats:p>\n<\/jats:sec>","DOI":"10.1371\/journal.pone.0280084","type":"journal-article","created":{"date-parts":[[2023,1,20]],"date-time":"2023-01-20T18:57:19Z","timestamp":1674241039000},"page":"e0280084","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":7,"title":["Induced abortion among female students in higher education institutions in Ethiopia: A systematic review and 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National Reproductive Health Strategy: 2016\u20132020. http:\/\/corhaethiopia.org\/wp-content\/uploads\/2016\/08\/RH-strategy-2016.pdf"},{"key":"pone.0280084.ref027","unstructured":"Federal Democratic Republic of Ethiopia Ministry of Education. Communication Strategy on HIV\/AIDS and Sexual Reproductive Health (SRH) for Higher Education Institution; 2013."},{"issue":"4","key":"pone.0280084.ref028","doi-asserted-by":"crossref","first-page":"W-65","DOI":"10.7326\/0003-4819-151-4-200908180-00136","article-title":"The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration","volume":"151","author":"A Liberati","year":"2009","journal-title":"Annals of internal medicine"},{"key":"pone.0280084.ref029","article-title":"AMSTAR 2: a critical appraisal tool for systematic reviews that include randomised or non-randomised studies of healthcare interventions, or both","volume":"358","author":"BJ Shea","year":"2017","journal-title":"bmj"},{"key":"pone.0280084.ref030","volume-title":"Joanna Briggs Institute Reviewers\u2019 Manual: 2014 edition","author":"The Joanna Briggs Institute","year":"2014"},{"issue":"7414","key":"pone.0280084.ref031","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1136\/bmj.327.7414.557","article-title":"Measuring inconsistency in meta-analyses","volume":"327","author":"JP Higgins","year":"2003","journal-title":"Bmj"},{"issue":"7109","key":"pone.0280084.ref032","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1136\/bmj.315.7109.629","article-title":"Bias in meta-analysis detected by a simple, graphical test","volume":"315","author":"M Egger","year":"1997","journal-title":"Bmj"},{"issue":"2","key":"pone.0280084.ref033","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1111\/j.0006-341X.2000.00455.x","article-title":"Trim and fill: a simple funnel-plot\u2013based method of testing and adjusting for publication bias in meta-analysis","volume":"56","author":"S Duval","year":"2000","journal-title":"Biometrics"},{"issue":"10","key":"pone.0280084.ref034","first-page":"127","article-title":"Assessment of Knowledge, Attitude and Practice towards the Use of Medication Abortion among Female Regular Undergraduate Students in Faculty of Health Science, Jimma University, South-West Ethiopia","volume":"4","author":"C Romano","year":"2020","journal-title":"Acta Scientific Pharmaceutical Sciences"},{"issue":"1","key":"pone.0280084.ref035","doi-asserted-by":"crossref","first-page":"58","DOI":"10.5455\/msm.2017.29.58-67","article-title":"Induced abortion: a systematic review and meta-analysis","volume":"29","author":"S Dastgiri","year":"2017","journal-title":"Materia socio-medica"},{"key":"pone.0280084.ref036","article-title":"Risk and protective factors affecting adolescent reproductive health in developing countries Geneva:Department of Population and Family Health Sciences","author":"RW Blum","year":"2005","journal-title":"Johns HopkinsBloomberg School of Public Health"},{"key":"pone.0280084.ref037","first-page":"94","article-title":"Sexual Harassment at African Higher Education Institutions","author":"C. 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