{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T03:02:00Z","timestamp":1787022120110,"version":"build-2736575974"},"reference-count":23,"publisher":"Public Library of Science (PLoS)","issue":"2","license":[{"start":{"date-parts":[[2023,2,9]],"date-time":"2023-02-09T00:00:00Z","timestamp":1675900800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["18K17676"],"award-info":[{"award-number":["18K17676"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["19K19901"],"award-info":[{"award-number":["19K19901"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Understanding typical gait development is critical in developing suitable physical therapy methods for gait disorders. This study investigated the developmental changes and controlling mechanisms of straight gait.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec002\">\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      We conducted an experimental procedure among 90 participants, including 76 typically developing children and 14 healthy adults. The children were divided according to age into 3\u20134, 5\u20136, 7\u20138, and 9-10-year age groups. We created two indices to quantify straight gait using the extrapolated center of mass (XCOM; goal index, XCOM\n                      <jats:sub>G<\/jats:sub>\n                      and actual progress index, XCOM\n                      <jats:sub>P<\/jats:sub>\n                      ), which were calculated and compared between the groups. Stepwise multiple regression was used to examine the effects of each gait variable on XCOM\n                      <jats:sub>G<\/jats:sub>\n                      and XCOM\n                      <jats:sub>P<\/jats:sub>\n                      . To eliminate the effects of multicollinearity, correlation coefficients were calculated for all gait variables.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec003\">\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Both XCOM\n                      <jats:sub>G<\/jats:sub>\n                      and XCOM\n                      <jats:sub>P<\/jats:sub>\n                      decreased gradually with age and were significantly larger in the 3\u20134 and 5\u20136 year groups than in the adult group. Multiple regression analysis showed that step velocity, step width, and the coefficiente of variation (CV) of the step width had independent coefficients of variation for the XCOM\n                      <jats:sub>G<\/jats:sub>\n                      , and the symmetry index of step time, step width, and the CV of the step width had independent CV for the XCOM\n                      <jats:sub>P<\/jats:sub>\n                      . These variables were selected as significant variables. The results showed that meandering gait was more pronounced at younger ages. Furthermore, straight gait observed in adulthood was achieved by the age of 7.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec id=\"sec004\">\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      Pace (step velocity) and stability (step width and CV of step width) may contribute to XCOM\n                      <jats:sub>G<\/jats:sub>\n                      , which assesses the ability to proceed in the direction of the target. Stability and symmetry may contribute to XCOM\n                      <jats:sub>P<\/jats:sub>\n                      , which assesses the ability to walk straight in one\u2019s own direction of progress. Physical therapists could apply these indices in children to assess their ability to walk straight.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1371\/journal.pone.0281037","type":"journal-article","created":{"date-parts":[[2023,2,9]],"date-time":"2023-02-09T13:44:56Z","timestamp":1675950296000},"page":"e0281037","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":7,"title":["Developmental changes in straight gait in childhood"],"prefix":"10.1371","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4676-5546","authenticated-orcid":true,"given":"Saori","family":"Miyagishima","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5430-7628","authenticated-orcid":true,"given":"Hiroki","family":"Mani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yui","family":"Sato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4252-1045","authenticated-orcid":true,"given":"Takahiro","family":"Inoue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tadayoshi","family":"Asaka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoki","family":"Kozuka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2023,2,9]]},"reference":[{"key":"pone.0281037.ref001","doi-asserted-by":"crossref","first-page":"1747","DOI":"10.1007\/s00221-016-4592-x","article-title":"Gait patterns in children with developmental coordination disorder","volume":"234","author":"K Wilmut","year":"2016","journal-title":"Exp Brain Res"},{"key":"pone.0281037.ref002","doi-asserted-by":"crossref","first-page":"102584","DOI":"10.1016\/j.humov.2020.102584","article-title":"Gait Control in Children with Attention-Deficit\/Hyperactivity Disorder.","volume":"70","author":"Roger W. Simmons","year":"2020","journal-title":"Hum Mov Sci."},{"key":"pone.0281037.ref003","doi-asserted-by":"crossref","first-page":"336","DOI":"10.2106\/00004623-198062030-00004","article-title":"The development of mature gait","volume":"62","author":"DH Sutherland","year":"1980","journal-title":"J Bone Joint Surg Am"},{"key":"pone.0281037.ref004","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1002\/ajpa.1330890104","article-title":"Can we really walk straight?","volume":"89","author":"T. Uetake","year":"1992","journal-title":"Am J Phys Anthropol"},{"key":"pone.0281037.ref005","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1017\/S0012162204000891","article-title":"Development of displacement of centre of mass during independent walking in children","volume":"46","author":"F Dierick","year":"2004","journal-title":"Dev Med Child Neurol"},{"key":"pone.0281037.ref006","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jbiomech.2004.03.025","article-title":"The condition for dynamic stability","volume":"38","author":"AL Hof","year":"2005","journal-title":"J Biomech"},{"key":"pone.0281037.ref007","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.gaitpost.2018.04.019","article-title":"Developmental changes in spatial margin of stability in typically developing children relate to the mechanics of gait.","volume":"63","author":"A Hallemans","year":"2018","journal-title":"Gait Posture"},{"key":"pone.0281037.ref008","first-page":"560","article-title":"Characteristics of the five functional domains about gait performance: Comparison between 3\u201310 years old children and healthy adults","volume":"47","author":"H Mani","year":"2020","journal-title":"J Jpn Phys Ther Assoc"},{"key":"pone.0281037.ref009","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1093\/gerona\/gls255","article-title":"Independent domains of gait in older adults and associated motor and nonmotor attributes: Validation of a factor analysis approach","volume":"68","author":"S Lord","year":"2013","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"pone.0281037.ref010","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1016\/0021-9290(86)90012-6","article-title":"Body segment mass, radius and radius of gyration proportions of children","volume":"19","author":"RK Jensen","year":"1986","journal-title":"J Biomech"},{"key":"pone.0281037.ref011","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/0966-6362(95)01057-2","article-title":"Scaling gait data to body size.","volume":"4","author":"AL Hof","year":"1996","journal-title":"Gait Posture."},{"key":"pone.0281037.ref012","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1002\/mds.26110","article-title":"Progression of gait dysfunction in incident Parkinson\u2019s disease: Impact of medication and phenotype","volume":"30","author":"B Galna","year":"2015","journal-title":"Mov Disord"},{"key":"pone.0281037.ref013","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1016\/j.gaitpost.2012.09.025","article-title":"Is gait variability reliable in older adults and Parkinson\u2019s disease? 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