{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T03:12:49Z","timestamp":1793157169902,"version":"4.5.0"},"reference-count":32,"publisher":"Public Library of Science (PLoS)","issue":"3","license":[{"start":{"date-parts":[[2023,3,31]],"date-time":"2023-03-31T00:00:00Z","timestamp":1680220800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"National Research Foundation of Korea(NRF) grant funded by the Korea governmen","award":["NRF-2019R1C1C1010352"],"award-info":[{"award-number":["NRF-2019R1C1C1010352"]}]},{"name":"Korea Medical Device Development Fund grant funded by the Korea government","award":["RS-2020-KD000308"],"award-info":[{"award-number":["RS-2020-KD000308"]}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\">\n<jats:title>Background<\/jats:title>\n<jats:p>This study investigated the epidemiology and demographics of slipped capital femoral epiphysis (SCFE) in South Korea using a nationwide population-based database.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec002\">\n<jats:title>Methods<\/jats:title>\n<jats:p>Information on sex, age at onset, endocrine comorbidities, history of growth hormone therapy, history of radiation therapy, surgical methods, and complications in patients with SCFE aged younger than 18 years between 2007 and 2019 was retrieved from the Korean Health Insurance Review and Assessment Service database.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec003\">\n<jats:title>Results<\/jats:title>\n<jats:p>Data were available for 586 children (429 boys, 157 girls). The average age at onset was 11.1 \u00b1 1.8 years (boys, 11.3 \u00b1 1.9; girls, 10.6 \u00b1 1.5). Five hundred and twenty-nine (90.3%) patients were aged 9\u201314 years; the incidence rate in this age group was 6.0\/100,000 (95% confidence interval, 5.5\u20136.6) and significantly higher in boys (8.4 vs 3.5, p&lt;0.001). There was a significant increase in the annual incidence rate from 0.96\/100,000 in 2009 to 2.05\/100,000 in 2019 (p = 0.006). Ninety-five patients (16.2%) had endocrine comorbidities or a history of hormone\/radiation therapy. Osteotomy and internal fixation were performed in 59 patients and in situ pinning in 527. Seventy-six patients developed postoperative complications.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec004\">\n<jats:title>Conclusion<\/jats:title>\n<jats:p>The annual incidence rate of SCFE in South Korea has increased since 2009.<\/jats:p>\n<\/jats:sec>","DOI":"10.1371\/journal.pone.0283123","type":"journal-article","created":{"date-parts":[[2023,3,31]],"date-time":"2023-03-31T17:47:26Z","timestamp":1680284846000},"page":"e0283123","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":7,"title":["Epidemiology and demographics of slipped capital femoral epiphysis in South Korea: A nationwide cohort study"],"prefix":"10.1371","volume":"18","author":[{"given":"Nak Tscheol","family":"Kim","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jae Jung","family":"Min","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eunjeong","family":"Ji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moon Seok","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5007-2403","authenticated-orcid":true,"given":"Ki Hyuk","family":"Sung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2023,3,31]]},"reference":[{"issue":"1","key":"pone.0283123.ref001","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1186\/s12891-017-1665-3","article-title":"Slipped capital femoral epiphysis: a population-based study","volume":"18","author":"B Herngren","year":"2017","journal-title":"BMC Musculoskelet Disord"},{"issue":"5","key":"pone.0283123.ref002","doi-asserted-by":"crossref","first-page":"667","DOI":"10.2106\/00004623-199173050-00004","article-title":"Long-term follow-up of slipped capital femoral epiphysis","volume":"73","author":"BT Carney","year":"1991","journal-title":"J Bone Joint Surg Am"},{"issue":"322","key":"pone.0283123.ref003","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1097\/00003086-199601000-00006","article-title":"Natural history of untreated chronic slipped capital femoral epiphysis","author":"BT Carney","year":"1996","journal-title":"Clin Orthop Relat Res"},{"issue":"2","key":"pone.0283123.ref004","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1097\/00004694-199703000-00013","article-title":"Slipped capital femoral epiphysis associated with renal failure osteodystrophy","volume":"17","author":"RT Loder","year":"1997","journal-title":"J Pediatr Orthop"},{"issue":"5","key":"pone.0283123.ref005","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1097\/01241398-199313050-00011","article-title":"Review of slipped capital femoral epiphysis associated with endocrine disease","volume":"13","author":"D Wells","year":"1993","journal-title":"J Pediatr Orthop"},{"issue":"3","key":"pone.0283123.ref006","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1097\/01241398-199505000-00018","article-title":"Slipped capital femoral epiphysis associated with endocrine disorders","volume":"15","author":"RT Loder","year":"1995","journal-title":"J Pediatr Orthop"},{"issue":"4","key":"pone.0283123.ref007","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1007\/BF00185232","article-title":"Slipped capital femoral epiphysis associated with hyperparathyroidism. 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