{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T14:08:09Z","timestamp":1740146889007,"version":"3.37.3"},"reference-count":18,"publisher":"Public Library of Science (PLoS)","issue":"3","license":[{"start":{"date-parts":[[2023,3,21]],"date-time":"2023-03-21T00:00:00Z","timestamp":1679356800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000272","name":"National Institute for Health and Care Research","doi-asserted-by":"publisher","award":["NIHR200601"],"award-info":[{"award-number":["NIHR200601"]}],"id":[{"id":"10.13039\/501100000272","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000265","name":"Medical Research Council","doi-asserted-by":"publisher","award":["MR\/N013913\/1"],"award-info":[{"award-number":["MR\/N013913\/1"]}],"id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\">\n<jats:title>Objective<\/jats:title>\n<jats:p>In a large-scale population cardiovascular screening programme, peripheral artery disease (PAD) and hypertension would ideally be rapidly assessed using a single device. The ankle-brachial pressure index (ABPI) is calculated by comparing the ankle and brachial blood pressure (BP). However, it is currently unclear whether brachial BP measurements provided by automated PAD screening systems are sufficiently accurate for simultaneous hypertension screening.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec002\">\n<jats:title>Methods<\/jats:title>\n<jats:p>Two portable PAD screening devices, the MESI ABPI MD and Huntleigh\u2019s Dopplex ABIlity, were evaluated following the European Society of Hypertension International Protocol (ESH-IP) Revision 2010 using a mercury-free sphygmomanometer as a reference device.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec003\">\n<jats:title>Results<\/jats:title>\n<jats:p>On average, the MESI slightly underestimated brachial systolic blood pressure (BP) with a bias and standard deviation (SD) of -3.5 (SD: 3.3) mmHg and diastolic BP with a bias of -1.5 (SD: 2.3) mmHg. For systolic BP estimates, the Dopplex was more accurate than the MESI with a lower bias of -0.5 (SD: 4.2) mmHg but less precise. The MESI successfully fulfilled all the requirements of the ESH-IP for hypertension screening. The Dopplex device failed the ESH-IP due to the absence of DBP measurements.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec004\">\n<jats:title>Conclusions<\/jats:title>\n<jats:p>The MESI device appears to be suitable for simultaneous PAD and hypertension screening as part of a preventative care programme. Huntleigh\u2019s Dopplex ABIlity failed to pass the ESH-IP validation test. Further clinical trials are underway to assess the use of the MESI for simultaneous screening for hypertension and PAD in a population screening setting.<\/jats:p>\n<\/jats:sec>","DOI":"10.1371\/journal.pone.0283281","type":"journal-article","created":{"date-parts":[[2023,3,21]],"date-time":"2023-03-21T17:31:31Z","timestamp":1679419891000},"page":"e0283281","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":0,"title":["Are portable ankle brachial pressure index measurement devices suitable for hypertension screening?"],"prefix":"10.1371","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1951-3861","authenticated-orcid":true,"given":"Justyna","family":"Janus","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2741-3652","authenticated-orcid":true,"given":"Jennifer K.","family":"Nicholls","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edward","family":"Pallett","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew","family":"Bown","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emma M. L.","family":"Chung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2023,3,21]]},"reference":[{"issue":"18","key":"pone.0283281.ref001","doi-asserted-by":"crossref","first-page":"1862","DOI":"10.1161\/CIRCULATIONAHA.109.918417","article-title":"Inflammation in Peripheral Artery Disease.","volume":"122","author":"G Brevetti","year":"2010","journal-title":"Circulation"},{"issue":"1","key":"pone.0283281.ref002","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.jvs.2013.03.044","article-title":"The toe-brachial index in the diagnosis of peripheral arterial disease","volume":"58","author":"C H\u00f8yer","year":"2013","journal-title":"Journal of Vascular Surgery"},{"issue":"1","key":"pone.0283281.ref003","doi-asserted-by":"crossref","first-page":"63","DOI":"10.4093\/dmj.2018.42.1.63","article-title":"Color Doppler Ultrasonography Is a Useful Tool for Diagnosis of Peripheral Artery Disease in Type 2 Diabetes Mellitus Patients with Ankle-Brachial Index 0.91 to 1.40","volume":"42","author":"KY Hur","year":"2018","journal-title":"Diabetes & metabolism journal"},{"issue":"24","key":"pone.0283281.ref004","doi-asserted-by":"crossref","first-page":"2890","DOI":"10.1161\/CIR.0b013e318276fbcb","article-title":"Measurement and interpretation of the ankle-brachial index: a scientific statement from the American Heart Association","volume":"126","author":"V Aboyans","year":"2012","journal-title":"Circulation"},{"key":"pone.0283281.ref005","first-page":"12","article-title":"The reliability of the ankle brachial index: a systematic review","author":"S Casey","year":"2019","journal-title":"Journal of foot and ankle research"},{"issue":"2","key":"pone.0283281.ref006","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1177\/154431671303700203","article-title":"Comparison of Automated Oscillometric Measurement of Ankle Brachial Index with Standard Doppler Measurement as a Screening Tool for Peripheral Artery Disease.","volume":"37","author":"A Jayaraj","year":"2013","journal-title":"Journal for Vascular Ultrasound"},{"issue":"11","key":"pone.0283281.ref007","doi-asserted-by":"crossref","first-page":"e0224546","DOI":"10.1371\/journal.pone.0224546","article-title":"Nurses\u2019 and patients\u2019 experiences and preferences of the ankle-brachial pressure index and multi-site photoplethysmography for the diagnosis of peripheral arterial disease: A qualitative study","volume":"14","author":"J Scott","year":"2019","journal-title":"PloS one"},{"issue":"2","key":"pone.0283281.ref008","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1038\/hr.2015.124","article-title":"Automated plethysmographic measurement of the ankle-brachial index: a comparison with the doppler ultrasound method","volume":"39","author":"JH Davies","year":"2016","journal-title":"Hypertens Res"},{"issue":"6","key":"pone.0283281.ref009","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1016\/j.ejvs.2022.08.008","article-title":"Selecting Portable Ankle\/Toe Brachial Pressure Index Systems for a Peripheral Arterial Disease Population Screening Programme: a Systematic Review, Clinical Evaluation Exercise, and Consensus Process","volume":"64","author":"EL Watson","year":"2022","journal-title":"Eur J Vasc Endovasc Surg"},{"issue":"1","key":"pone.0283281.ref010","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1097\/MBP.0b013e3283360e98","article-title":"European Society of Hypertension International Protocol revision 2010 for the validation of blood pressure measuring devices in adults","volume":"15","author":"E O\u2019Brien","year":"2010","journal-title":"Blood Press Monit"},{"issue":"7238","key":"pone.0283281.ref011","first-page":"815","article-title":"Replacing the mercury sphygmomanometer. Requires clinicians to demand better automated devices","volume":"320","author":"E. O\u2019Brien","year":"2000","journal-title":"BMJ (Clinical research ed)."},{"issue":"9","key":"pone.0283281.ref012","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1038\/jhh.2009.113","article-title":"Development and validation of a blinded hybrid device according to the European Hypertension Society protocol: Nissei DM-3000.","volume":"24","author":"F Tasker","year":"2010","journal-title":"J Hum Hypertens"},{"key":"pone.0283281.ref013","unstructured":"Nissei. Mercury column image digital sphygmomanometer DM-3000 instruction manual Medaval: Nissei; [Available from: https:\/\/medaval.ie\/device\/nissei-dm-3000\/."},{"key":"pone.0283281.ref014","unstructured":"Huntleigh. HUNTLEIGH Dopplex ABIlity INSTRUCTIONS FOR USE [User Manual]. Huntleigh Healthcare Ltd. 2011 [Available from: https:\/\/irp-cdn.multiscreensite.com\/a7c96b08\/files\/uploaded\/771438EN-11_Dopplex_Ability_Instructions_for_Use-English.pdf"},{"key":"pone.0283281.ref015","unstructured":"MESI. MESI ABPI MD INSTRUCTIONS FOR USE [User manual]. MESI; 2017 [Available from: https:\/\/www.mesimedical.com\/app\/uploads\/2019\/11\/ABPIMD_IFU_ENG_v7-2_2019-07-05_web.pdf."},{"issue":"20","key":"pone.0283281.ref016","doi-asserted-by":"crossref","first-page":"2191","DOI":"10.1001\/jama.2013.281053","article-title":"World Medical Association Declaration of Helsinki: ethical principles for medical research involving human subjects","volume":"310","year":"2013","journal-title":"Jama"},{"issue":"1","key":"pone.0283281.ref017","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1097\/00126097-200202000-00002","article-title":"Working Group on Blood Pressure Monitoring of the European Society of Hypertension International Protocol for validation of blood pressure measuring devices in adults","volume":"7","author":"E O\u2019Brien","year":"2002","journal-title":"Blood Press Monit"},{"key":"pone.0283281.ref018","doi-asserted-by":"crossref","first-page":"305","DOI":"10.2147\/VHRM.S106534","article-title":"Detection of peripheral arterial disease with an improved automated device: comparison of a new oscillometric device and the standard Doppler method.","volume":"12","author":"M \u0160pan","year":"2016","journal-title":"Vascular health and risk management"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0283281","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,21]],"date-time":"2023-03-21T17:31:54Z","timestamp":1679419914000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0283281"}},"subtitle":[],"editor":[{"given":"Mohamed Yacin","family":"Sikkandar","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2023,3,21]]},"references-count":18,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2023,3,21]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0283281","relation":{},"ISSN":["1932-6203"],"issn-type":[{"type":"electronic","value":"1932-6203"}],"subject":[],"published":{"date-parts":[[2023,3,21]]}}}