{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T01:15:46Z","timestamp":1791335746199,"version":"4.3.1"},"reference-count":81,"publisher":"Public Library of Science (PLoS)","issue":"4","license":[{"start":{"date-parts":[[2023,4,26]],"date-time":"2023-04-26T00:00:00Z","timestamp":1682467200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Fonds de Recherche du Qu\u00e9bec-Sant\u00e9 doctoral fellowship"},{"name":"CICC"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:p>Substance use disorder is a worldwide issue that entails negative health and physical activity is a promising complementary therapy for alleviating the consequences. The objective of this reviews is to characterize physical activity interventions offered in the literature and explore their effects during treatment for people with substance use disorders with excluding studies focusing only on tobacco use. A systematic search of seven databases on articles including a physical activity intervention during a treatment for substance use disorder was done and an examination of the presence of bias was performed. A total of 43 articles including 3135 participants were identified. Most studies were randomized controlled trial (81%), followed by pre-post design (14%) and cohort studies (5%). The most common physical activity intervention identified was of moderate intensity, 3 times per week (\u2248 1 hour) for 13 weeks. Cessation\/reduction of substance use was the most studied outcome (21 studies, 49%), and 75% showed a decrease in substance use following physical activity intervention. Aerobic capacity was the second most studied effect (14 studies, 33%), with more than 71% of studies showing improvement. Twelve studies (28%) reported a decrease of depressive symptoms. Physical activity interventions in a treatment for substance use disorder seem to be a promising, but more methodologically rigorous scientific studies are needed.<\/jats:p>","DOI":"10.1371\/journal.pone.0283861","type":"journal-article","created":{"date-parts":[[2023,4,26]],"date-time":"2023-04-26T13:21:26Z","timestamp":1682515286000},"page":"e0283861","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":37,"title":["Characteristics and impact of physical activity interventions during substance use disorder treatment excluding tobacco: A systematic review"],"prefix":"10.1371","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8719-3751","authenticated-orcid":true,"given":"Florence","family":"Pich\u00e9","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Daneau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chantal","family":"Plourde","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"St\u00e9phanie","family":"Girard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1690-1375","authenticated-orcid":true,"given":"Ahmed J\u00e9r\u00f4me","family":"Romain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2023,4,26]]},"reference":[{"key":"pone.0283861.ref001","unstructured":"Ritchie H, Roser M. Drug use. Available at: https:\/\/ourworldindata.org\/drug-use [accessed 20. 06.2021]."},{"key":"pone.0283861.ref002","article-title":"Global health data exchange","author":"Institute for Health Metrics and Evaluation"},{"key":"pone.0283861.ref003","first-page":"947","article-title":"Dsm-v: Diagnostic and statistical manual of mental disorders","author":"American Psychiatric Association","year":"2013","journal-title":"5 ed. Washington: Amerian Psychiatric Publishing"},{"key":"pone.0283861.ref004","first-page":"1","article-title":"Substance use and associated health conditions throughout the lifespan","volume":"35","author":"MT Schulte","year":"2014","journal-title":"Public Health Reviews"},{"key":"pone.0283861.ref005","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1001\/jamapsychiatry.2015.2688","article-title":"Association of Mental Disorders With Subsequent Chronic Physical Conditions: World Mental Health Surveys From 17","volume":"73","author":"KM Scott","year":"2015","journal-title":"Countries. JAMA Psychiatry"},{"key":"pone.0283861.ref006","first-page":"60","author":"Nationale Institute on Drug Abuse","year":"2018","journal-title":"Principles of drug addicion treatment: a research-based guide"},{"key":"pone.0283861.ref007","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.drugalcdep.2019.03.031","article-title":"The effectiveness of residential treatment services for individuals with substance use disorders: A systematic review","volume":"201","author":"D De Andrade","year":"2019","journal-title":"Drug and alcohol dependence"},{"key":"pone.0283861.ref008","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1111\/add.14793","article-title":"Dropout rates of in-person psychosocial substance use disorder treatments: A systematic review and meta-analysis","volume":"115","author":"SN Lappan","year":"2020","journal-title":"Addictio"},{"key":"pone.0283861.ref009","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/j.drugalcdep.2016.08.625","article-title":"Remission from substance use disorders: A systematic review and meta-analysis","volume":"168","author":"MJ Fleury","year":"2016","journal-title":"Drug and alcohol dependence"},{"key":"pone.0283861.ref010","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1080\/1533256X.2016.1200055","article-title":"Mapping the evidence to improve retention rates in addiction services","volume":"16","author":"KS Perkins","year":"2016","journal-title":"J. Soc. Work Pract. Addict"},{"key":"pone.0283861.ref011","first-page":"472","article-title":"Guidelines for Exercise Testing and Prescription","author":"American College of Sports Medicine","year":"2018","journal-title":"Philadelphia: Wolters Kluwer"},{"key":"pone.0283861.ref012","article-title":"Exercise as medicine for mental and substance use disorders: A meta-review of the benefits for neuropsychiatric and cognitive outcomes","author":"G Ashdown-Franks","year":"2019","journal-title":"Sports Med"},{"key":"pone.0283861.ref013","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.eurpsy.2018.07.004","article-title":"EPA guidance on physical activity as a treatment for severe mental illness: a meta-review of the evidence and Position Statement from the European Psychiatric Association (EPA), supported by the International Organization of Physical Therapists in Mental Health (IOPTMH)","volume":"54","author":"B Stubbs","year":"2018","journal-title":"Eur psychiatr"},{"key":"pone.0283861.ref014","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1111\/j.1360-0443.2012.04034.x","article-title":"The acute effects of physical activity on cigarette cravings: Systematic review and meta-analysis with individual participant data","volume":"108","author":"M Haasova","year":"2012","journal-title":"Addiction"},{"issue":"14","key":"pone.0283861.ref015","doi-asserted-by":"crossref","first-page":"2765","DOI":"10.1007\/s00213-016-4326-6","article-title":"The association between habitual physical activity and cigarette cravings, and influence of smokers\u2019 characteristics in disadvantaged smokers not ready to quit","volume":"233","author":"M Haasova","year":"2016","journal-title":"Psychopharmacology"},{"key":"pone.0283861.ref016","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fpsyt.2018.00644","article-title":"Anaerobic exercise training in the therapy of substance use disorders: A systematic review","volume":"9","author":"F Colledge","year":"2018","journal-title":"Front. Psychiatry"},{"key":"pone.0283861.ref017","first-page":"1","article-title":"Impact of physical exercise on substance use disorders: A meta-analysis","volume":"9","author":"D Wang","year":"2014","journal-title":"PLoS One"},{"key":"pone.0283861.ref018","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1136\/bjsports-2016-096814","article-title":"Exercise as treatment for alcohol use disorders: Systematic review and meta-analysis","volume":"51","author":"M Hallgren","year":"2017","journal-title":"Br J Sports Med"},{"key":"pone.0283861.ref019","doi-asserted-by":"crossref","first-page":"535","DOI":"10.3892\/br.2016.626","article-title":"Role of exercise in the treatment of alcohol use disorders","volume":"4","author":"E Manthou","year":"2016","journal-title":"Biomed Rep"},{"key":"pone.0283861.ref020","first-page":"1","article-title":"Common Comorbidities with Substance Use Disorders Research Report","author":"National Institute on Drug 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Res"},{"key":"pone.0283861.ref027","doi-asserted-by":"crossref","first-page":"l4898","DOI":"10.1136\/bmj.l4898","article-title":"Rob 2: A revised tool for assessing risk of bias in randomised trials","volume":"366","author":"JAC Sterne","year":"2019","journal-title":"BMJ"},{"key":"pone.0283861.ref028","article-title":"Study Quality Assessment Tools","author":"National Heart, Lung, and Blood Institute"},{"key":"pone.0283861.ref029","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1590\/1517-869220172304173106","article-title":"Effects of exercise on physical fitness and anthropometric variables in ex-crack cocaine users. \/ efectos del ejercicio sobre la aptitud f\u00edsica y las variables antropom\u00e9tricas en los ex-usuarios de crack","volume":"23","author":"J Abatti Martins","year":"2017","journal-title":"Revista Brasileira de Medicina do Esporte"},{"issue":"1","key":"pone.0283861.ref030","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jsat.2014.02.004","article-title":"A preliminary, randomized trial of aerobic exercise for alcohol dependence","volume":"47","author":"RA Brown","year":"2014","journal-title":"Journal of Substance Abuse Treatment"},{"issue":"2","key":"pone.0283861.ref031","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1177\/0145445508329112","article-title":"Aerobic Exercise for Alcohol Recovery: Rationale, Program Description, and Preliminary Findings","volume":"33","author":"RA Brown","year":"2009","journal-title":"Behav Modif"},{"key":"pone.0283861.ref032","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.mhpa.2010.03.001","article-title":"A pilot study of aerobic exercise as an adjunctive treatment for drug dependence","volume":"3","author":"RA Brown","year":"2010","journal-title":"Ment Health Phys 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Disability &","volume":"25","author":"EM Capodaglio","year":"2003","journal-title":"Rehabilitation"},{"key":"pone.0283861.ref035","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.conctc.2018.02.001","article-title":"A complier average causal effect analysis of the stimulant reduction intervention using dosed exercise study","volume":"10","author":"T Carmody","year":"2018","journal-title":"Contemp Clin Trials Commun"},{"key":"pone.0283861.ref036","doi-asserted-by":"crossref","first-page":"798","DOI":"10.1249\/01.MSS.0000402221.91129.73","article-title":"Eight weeks of exercise training improves fitness measures in methamphetamine-dependent individuals in residential treatment","volume":"43","author":"BA Dolezal","year":"2013","journal-title":"Med Sci Sports Exerc"},{"key":"pone.0283861.ref037","doi-asserted-by":"crossref","first-page":"39","DOI":"10.3928\/0279-3695-19970701-23","article-title":"Impact of a body-mind treatment component on alcoholic inpatients","volume":"35","author":"R Ermalinski","year":"1997","journal-title":"J Psychosoc Nurs Men. Health Serv"},{"key":"pone.0283861.ref038","article-title":"A mixed-method investigation into therapeutic yoga as an adjunctive treatment for people recovering from substance use disorders","author":"C Fitzgerald","year":"2020","journal-title":"Int J Ment Health Addict"},{"key":"pone.0283861.ref039","doi-asserted-by":"crossref","first-page":"616935","DOI":"10.1155\/2014\/616935","article-title":"High-intensity interval training in patients with substance use disorder","volume":"2014","author":"G Flemmen","year":"2014","journal-title":"Biomed Res Int"},{"key":"pone.0283861.ref040","doi-asserted-by":"crossref","first-page":"1272","DOI":"10.15288\/qjsa.1974.35.1272","article-title":"Physical fitness and personality in alcoholism; canonical analysis of measures before and after treatment","volume":"35","author":"A Frankel","year":"1974","journal-title":"Alcohol Treat Q"},{"key":"pone.0283861.ref041","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1159\/000484165","article-title":"Effect of add-on yoga on cognitive functions among substance abusers in a residential therapeutic center: Randomized comparative study","volume":"25","author":"A Gaihre","year":"2018","journal-title":"Ann Neurosci"},{"key":"pone.0283861.ref042","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.15288\/qjsa.1972.33.1073","article-title":"The effect of jogging on physical fitness and self-concept in hospitalized alcoholics","volume":"33","author":"V Gary","year":"1972","journal-title":"Alcohol Treat Q"},{"key":"pone.0283861.ref043","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1080\/07347324.2016.1113109","article-title":"Effects of an exercise program on physical activity level and quality of life in patients with severe alcohol dependence","volume":"34","author":"ES Giesen","year":"2016","journal-title":"Alcohol Treat 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Exercise on Cognitive Function in Women With Methamphetamine Dependence in a Detoxification Program in Tianjin, China: A Randomized Controlled Trial","volume":"29","author":"J Liu","year":"2021","journal-title":"Journal of Nursing Research"},{"issue":"1","key":"pone.0283861.ref048","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1007\/s11571-020-09647-w","article-title":"Effects of exercise programs on neuroelectric dynamics in drug addiction","volume":"15","author":"Y Lu","year":"2020","journal-title":"Cognitive Neurodynamics"},{"issue":"3","key":"pone.0283861.ref049","doi-asserted-by":"crossref","first-page":"e13211","DOI":"10.1111\/jsr.13211","article-title":"The effect of daily aerobic cycling exercise on sleep quality during inpatient cannabis withdrawal: A randomised controlled trial","volume":"30","author":"D McCartney","year":"2021","journal-title":"J Sleep 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Rawson","year":"2015","journal-title":"J Subst Abuse Treat"},{"key":"pone.0283861.ref056","doi-asserted-by":"crossref","first-page":"e186","DOI":"10.1016\/j.drugalcdep.2015.07.501","article-title":"Impact of an exercise intervention on methamphetamine use outcomes post residential treatment care","volume":"156","author":"R Rawson","year":"2015","journal-title":"Drug Alcohol Depend"},{"key":"pone.0283861.ref057","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1177\/1403494810371249","article-title":"Exercise treatment for drug abuse-a danish pilot study","volume":"38","author":"KK Roessler","year":"2010","journal-title":"Scand J Public Health"},{"key":"pone.0283861.ref058","doi-asserted-by":"crossref","first-page":"e0186076","DOI":"10.1371\/journal.pone.0186076","article-title":"Exercise as adjunctive treatment for alcohol use disorder: A randomized controlled trial","volume":"12","author":"KK Roessler","year":"2017","journal-title":"PLoS 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Abuse"},{"key":"pone.0283861.ref071","first-page":"260","article-title":"Yoga effects on mood and quality of life in chinese women undergoing heroin detoxification","volume":"62","author":"SM Zhuang","year":"2013","journal-title":"A randomized controlled trial. 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