{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T13:42:56Z","timestamp":1791812576127,"version":"4.3.4"},"reference-count":64,"publisher":"Public Library of Science (PLoS)","issue":"5","license":[{"start":{"date-parts":[[2023,5,4]],"date-time":"2023-05-04T00:00:00Z","timestamp":1683158400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100009914","name":"Makerere University","doi-asserted-by":"publisher","award":["MAK\/DVCFA\/113\/20"],"award-info":[{"award-number":["MAK\/DVCFA\/113\/20"]}],"id":[{"id":"10.13039\/501100009914","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\">\n<jats:title>Background<\/jats:title>\n<jats:p>Mental disorders are known to predict poverty, morbidity and mortality. In resource limited settings, low levels of mental health literacy (MHL) and high mental illness stigma (MIS) have been sighted as possible factors that may impede access to mental health care. However, little has been done to examine the association between mental disorders and these factors (MHL and MIS) in sub-Saharan Africa.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec002\">\n<jats:title>Methods<\/jats:title>\n<jats:p>We assessed for the prevalence of major depressive disorders (MDD), substance use disorders (SUD), post-traumatic stress disorder (PTSD), generalized anxiety disorder (GAD), documented MHL and MIS among 814 participants from 24 villages in central Uganda. We conducted regression analyses to examine the association between the prevalence of mental disorders, demographic factors as well as MIS and MHL.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec003\">\n<jats:title>Results<\/jats:title>\n<jats:p>Over two thirds of the participants 581 (70%) were female. The mean age of the participants was 38 years (SD\u00b1 13.5). The prevalence of mental disorders ranged from 6.8\u201332%. Participants who were older were less likely to screen positive for GAD (OR 0.98; 0.96\u20130.99), female gender was protective against SUD (OR 0.46; 0.3\u20130.68) and those with MDD had lower education level (OR 0.23; 0.1\u20130.53). The mean MIS score was 11.3 (SD\u00b1 5.4) with a range of 6\u201330 and the mean MHL score was 21.7 (SD \u00b13.0) with a range of 10\u201330. MIS was negatively associated with GAD [\u03b2 = -1.211 (-2.382 to -0.040)]. There no statistically significant association between MHL and a mental disorder.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec004\">\n<jats:title>Conclusion<\/jats:title>\n<jats:p>There was a high prevalence of mental disorders in the community that we studied. Adequate resources should be allocated to address this burden.<\/jats:p>\n<\/jats:sec>","DOI":"10.1371\/journal.pone.0285091","type":"journal-article","created":{"date-parts":[[2023,5,4]],"date-time":"2023-05-04T18:07:41Z","timestamp":1683223661000},"page":"e0285091","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":13,"title":["The prevalence and factors associated with mental disorders in a community setting in central Uganda"],"prefix":"10.1371","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8886-4553","authenticated-orcid":true,"given":"Dickens","family":"Akena","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronald","family":"Kiguba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wilson W.","family":"Muwhezi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brendan","family":"Kwesiga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gwendolyne","family":"Kigozi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hafsa","family":"Lukwata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noeline","family":"Nakasujja","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2023,5,4]]},"reference":[{"issue":"5","key":"pone.0285091.ref001","article-title":"The prevalence of mental health problems in sub-Saharan adolescents: A systematic review","volume":"16","author":"Astrid J\u00f6rns-Presentati","year":"2021","journal-title":"PLoS ONE"},{"issue":"10","key":"pone.0285091.ref002","doi-asserted-by":"crossref","first-page":"e1375","DOI":"10.1016\/S2214-109X(19)30374-2","article-title":"Burden of non-communicable diseases in sub-Saharan Africa, 1990\u20132017: results from the Global Burden of Disease Study 2017","volume":"7","author":"Hebe N Gouda","year":"2019","journal-title":"Lancet Glob Health"},{"key":"pone.0285091.ref003","article-title":"Global, regional, and national burden of 12 mental disorders in 204 countries and territories, 1990\u20132019: a systematic analysis for the Global Burden of Disease Study 2019","author":"GBD 2019 Mental Disorders Collaborators","year":"2022","journal-title":"Lancet Psychiatry"},{"issue":"5","key":"pone.0285091.ref004","article-title":"National and regional prevalence of posttraumatic stress disorder in sub-Saharan Africa: A systematic review and meta-analysis","volume":"17","author":"Lauren C. 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