{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T05:34:15Z","timestamp":1790487255122,"version":"4.1.0"},"reference-count":79,"publisher":"Public Library of Science (PLoS)","issue":"5","license":[{"start":{"date-parts":[[2023,5,31]],"date-time":"2023-05-31T00:00:00Z","timestamp":1685491200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81774108"],"award-info":[{"award-number":["81774108"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81703898"],"award-info":[{"award-number":["81703898"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81973652"],"award-info":[{"award-number":["81973652"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\"><jats:title>Background<\/jats:title><jats:p>Postoperative nausea and vomiting are typical postsurgical complications. Drug therapy is only partially effective. The goal of our meta-analysis is to systematically evaluate the efficacy and safety of electrical acupoint stimulation for postoperative nausea and vomiting and to score the quality of evidence supporting this concept.<\/jats:p><\/jats:sec><jats:sec id=\"sec002\"><jats:title>Methods<\/jats:title><jats:p>PubMed, Embase, Cochrane Library, Web of Science, and ClinicalTrials.gov were searched from inception to March 19, 2020.<\/jats:p><\/jats:sec><jats:sec id=\"sec003\"><jats:title>Results<\/jats:title><jats:p>Twenty-six studies (2064 patients) were included. Compared with control treatment, electrical acupoint stimulation reduced the incidence of postoperative nausea and vomiting (RR 0.49, 95% CI 0.41 to 0.57, P &lt; 0.001), postoperative nausea (RR 0.55, 95% CI 0.47 to 0.64, P &lt; 0.001) and postoperative vomiting (RR 0.56, 95% CI 0.45 to 0.70, P &lt; 0.001). Electrical acupoint stimulation also reduced the number of patients requiring antiemetic rescue (RR 0.60, 95% CI 0.43 to 0.85, P = 0.004). No differences in adverse events were observed. Subgroup analysis showed that both electroacupuncture (RR 0.58, 95% CI 0.46 to 0.74, P &lt; 0.001) and transcutaneous electrical acupoint stimulation (RR 0.44, 95% CI 0.34 to 0.58, P &lt; 0.001) had significant effects. Electrical acupoint stimulation was effective whether administered preoperatively (RR 0.40, 95% CI 0.27 to 0.60, P &lt; 0.001), postoperatively (RR 0.59, 95% CI 0.46 to 0.76, P &lt; 0.001), or perioperatively (RR 0.50, 95% CI 0.37 to 0.67, P &lt; 0.001). The quality of evidence was moderate to low.<\/jats:p><\/jats:sec><jats:sec id=\"sec004\"><jats:title>Conclusions<\/jats:title><jats:p>Electrical acupoint stimulation probably reduce the incidence of postoperative nausea and vomiting, postoperative nausea, postoperative vomiting, and reduce the number of patients requiring antiemetic rescue, with few adverse events.<\/jats:p><\/jats:sec>","DOI":"10.1371\/journal.pone.0285943","type":"journal-article","created":{"date-parts":[[2023,5,31]],"date-time":"2023-05-31T18:03:25Z","timestamp":1685556205000},"page":"e0285943","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":23,"title":["Efficacy and safety of electrical acupoint stimulation for postoperative nausea and vomiting: A systematic review and meta-analysis"],"prefix":"10.1371","volume":"18","author":[{"given":"Liyue","family":"Lu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chenlong","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xing","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yalan","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiyu","family":"Yin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pan","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yue","family":"Yong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5358-3153","authenticated-orcid":true,"given":"Jiangang","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2023,5,31]]},"reference":[{"issue":"3","key":"pone.0285943.ref001","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1213\/ANE.0b013e318254285e","article-title":"Postoperative 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Stoicea","year":"2015","journal-title":"Frontiers in medicine."},{"issue":"10","key":"pone.0285943.ref017","doi-asserted-by":"crossref","first-page":"813","DOI":"10.2165\/00023210-200721100-00003","article-title":"Mechanisms underlying postoperative nausea and vomiting and neurotransmitter receptor antagonist-based pharmacotherapy","volume":"21","author":"TJ Gan","year":"2007","journal-title":"CNS drugs"},{"issue":"1","key":"pone.0285943.ref018","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1213\/ANE.0000000000000002","article-title":"Consensus guidelines for the management of postoperative nausea and vomiting.","volume":"118","author":"TJ Gan","year":"2014","journal-title":"Anesthesia and analgesia."},{"key":"pone.0285943.ref019","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.ejphar.2013.10.037","article-title":"Pathophysiological and neurochemical mechanisms of postoperative nausea and vomiting","volume":"722","author":"CC 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Hypertensive Rats.","volume":"2018","author":"Q Zhang","year":"2018","journal-title":"Neural plasticity."},{"issue":"1","key":"pone.0285943.ref029","doi-asserted-by":"crossref","DOI":"10.3390\/jcm10010146","article-title":"Transcutaneous Electrical Acupoint Stimulation Reduces Postoperative Analgesic Requirement in Patients Undergoing Inguinal Hernia Repair: A Randomized, Placebo-Controlled Study.","volume":"10","author":"M Szmit","year":"2021","journal-title":"Journal of clinical medicine"},{"key":"pone.0285943.ref030","first-page":"9645284221076517","article-title":"Preoperative electroacupuncture for postoperative nausea and vomiting in laparoscopic gynecological surgery: a randomized controlled trial.","volume":"2022","author":"J Zhu","journal-title":"Acupuncture in medicine: journal of the British Medical Acupuncture Society"},{"key":"pone.0285943.ref031","doi-asserted-by":"crossref","first-page":"766244","DOI":"10.3389\/fmed.2022.766244","article-title":"Transcutaneous Electrical 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electrical stimulation in preventing postoperativenausea and vomiting following laparoscopic surgery","volume":"46","author":"AH Yeoh","year":"2016","journal-title":"Turkish journal of medical sciences"},{"issue":"3","key":"pone.0285943.ref041","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1089\/acm.2005.11.407","article-title":"Transcutaneous electrical acupoint stimulation versus ondansetron in the prevention of postoperative vomiting following pediatric tonsillectomy","volume":"11","author":"AA Kabalak","year":"2005","journal-title":"Journal of alternative and complementary medicine"},{"issue":"3","key":"pone.0285943.ref042","first-page":"629","article-title":"The use of transcutaneous acupoint electrical stimulation for preventing nausea and vomiting after laparoscopic surgery","volume":"92","author":"E Z\u00e1rate","year":"2001","journal-title":"Anesthesia and analgesia"},{"key":"pone.0285943.ref043","first-page":"809","article-title":"Pain management using Han\u2019s 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