{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T18:20:30Z","timestamp":1787509230288,"version":"build-2736575974"},"reference-count":16,"publisher":"Public Library of Science (PLoS)","issue":"6","license":[{"start":{"date-parts":[[2023,6,2]],"date-time":"2023-06-02T00:00:00Z","timestamp":1685664000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"\n Background<\/jats:title>\n To report a long-term outcome of the novel combined surgical method of complete excision, corneal tattooing, and a sutureless limbal conjunctival autograft for limbal dermoid.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n All patients who were referred to our clinic for limbal dermoid, and underwent a combined surgery of complete excision, corneal tattooing, and a sutureless limbal conjunctival autograft were retrospectively reviewed. The surgery was performed by one surgeon, and all clinical information was obtained during a seven-year follow up period. In all patients, surgical outcomes of cosmesis, best corrected visual acuity (BCVA), spherical equivalent (SE), and corneal\/ocular astigmatism were obtained and compared preoperatively and postoperatively.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n During seven years, 24 patients (24 eyes) with limbal dermoid were finally enrolled. The mean age was 10.1\u00b18.9 years old. The surgery resulted in an improved appearing ocular surface in all cases without any complications. There was no statistical difference in BCVA, corneal and ocular astigmatism between preoperatively and postoperatively (p = 0.231, 0.156 and 0.475, respectively). The mean SE was 0.12\u00b13.19D preoperatively, and -0.21\u00b13.02 D postoperatively with statistical significance (p = 0.037). Mean follow up period was 54.50 \u00b1 15.62 months.<\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n Based on the results of this study, our innovative surgical method which includes complete excision with corneal tattooing and limbal conjunctival autograft can be a simple and safe procedure that achieves long standing cosmesis with limbal dermoids.<\/jats:p>\n <\/jats:sec>","DOI":"10.1371\/journal.pone.0286250","type":"journal-article","created":{"date-parts":[[2023,6,2]],"date-time":"2023-06-02T14:04:33Z","timestamp":1685714673000},"page":"e0286250","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":8,"title":["Novel limbal dermoid surgery for visual acuity and cosmesis improvement: A 7-year retrospective review"],"prefix":"10.1371","volume":"18","author":[{"given":"Jinho","family":"Jeong","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriel M.","family":"Rand","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ju-Yeun","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8353-4910","authenticated-orcid":true,"given":"Ji-Won","family":"Kwon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2023,6,2]]},"reference":[{"key":"pone.0286250.ref001","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.survophthal.2003.10.008","article-title":"Tumors of the conjunctiva and cornea","volume":"49","author":"CL Shields","year":"2004","journal-title":"Surv Ophthalmol"},{"key":"pone.0286250.ref002","first-page":"74","volume-title":"Developmental Abnormalities of the Eye","author":"I. Mann","year":"1957"},{"key":"pone.0286250.ref003","first-page":"279","article-title":"Aesthetic Considerations in Pediatric Oculoplastic Surgery.","author":"JA Foster","year":"2017","journal-title":"Pediatric Oculoplastic Surgery"},{"key":"pone.0286250.ref004","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1097\/ICO.0000000000000440","article-title":"New Surgical Approach for Limbal Dermoids in Children","volume":"34","author":"J Jeong","year":"2015","journal-title":"Cornea"},{"key":"pone.0286250.ref005","first-page":"463","article-title":"Simple keratectomy and corneal tattooing for limbal dermoids: results of a 3-year study.","volume":"6","author":"DM Cha","year":"2013","journal-title":"Int J Ophthalmol-chi"},{"key":"pone.0286250.ref006","first-page":"85","article-title":"Excision of limbal dermoids.","volume":"22","author":"RW Panton","year":"1991","journal-title":"Ophthalmic Surg."},{"key":"pone.0286250.ref007","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1038\/eye.2014.112","article-title":"Surgical management of corneal limbal dermoids: retrospective study of different techniques and use of Mitomycin C.","volume":"28","author":"SJ Lang","year":"2014","journal-title":"Eye."},{"key":"pone.0286250.ref008","doi-asserted-by":"crossref","first-page":"1858","DOI":"10.1016\/S0161-6420(01)00705-9","article-title":"Therapeutic lamellar keratoplasty for limbal dermoids","volume":"108","author":"JA Scott","year":"2001","journal-title":"Ophthalmology"},{"key":"pone.0286250.ref009","doi-asserted-by":"crossref","first-page":"1955.e1","DOI":"10.1016\/j.ophtha.2005.06.015","article-title":"Full-Thickness Central Corneal Grafts in Lamellar Keratoscleroplasty to Treat Limbal Dermoids","volume":"112","author":"Y-D Shen","year":"2005","journal-title":"Ophthalmology"},{"key":"pone.0286250.ref010","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1067\/mpa.2002.124651","article-title":"Outcome of lamellar keratoplasty for limbal dermoids in children.","volume":"6","author":"P Watts","year":"2002","journal-title":"J Am Assoc Pediatric Ophthalmol Strabismus"},{"key":"pone.0286250.ref011","doi-asserted-by":"crossref","first-page":"136","DOI":"10.3928\/0191-3913-19990501-11","article-title":"Treatment of Epibulbar Limbal Dermoids.","volume":"36","author":"A Kaufman","year":"1999","journal-title":"J Pediat Ophth Strab."},{"key":"pone.0286250.ref012","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1097\/ICO.0000000000000745","article-title":"Keratopigmentation to Change the Apparent Color of the Human Eye","volume":"35","author":"JL Ali\u00f3","year":"2016","journal-title":"Cornea"},{"key":"pone.0286250.ref013","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1111\/ceo.12501","article-title":"Unique case of eyeball tattooing leading to ocular penetration and intraocular tattoo pigment deposition.","volume":"43","author":"A Jalil","year":"2015","journal-title":"Clin Exp Ophthalmol."},{"key":"pone.0286250.ref014","doi-asserted-by":"crossref","first-page":"e7","DOI":"10.1097\/ICL.0000000000000257","article-title":"Shave Excision With Keratopigmentation for Limbal Dermoid.","volume":"44","author":"P Bandivadekar","year":"2018","journal-title":"Eye Contact Lens Sci Clin Pract."},{"key":"pone.0286250.ref015","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1186\/s12886-018-0790-6","article-title":"Optimal size of pterygium excision for limbal conjunctival autograft using fibrin glue in primary pterygia.","volume":"18","author":"HS Hwang","year":"2018","journal-title":"BMC Ophthalmol."},{"key":"pone.0286250.ref016","doi-asserted-by":"crossref","first-page":"241","DOI":"10.3928\/0191-3913-19960701-08","article-title":"Astigmatic Refractive Errors Associated With Limbal Dermoids.","volume":"33","author":"RM Robb","year":"1996","journal-title":"J Pediat Ophth Strab."}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0286250","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,2]],"date-time":"2023-06-02T14:05:15Z","timestamp":1685714715000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0286250"}},"subtitle":[],"editor":[{"given":"Bharat","family":"Gurnani","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2023,6,2]]},"references-count":16,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2023,6,2]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0286250","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,6,2]]}}}