{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,26]],"date-time":"2026-04-26T08:06:28Z","timestamp":1777190788505,"version":"3.51.4"},"reference-count":22,"publisher":"Public Library of Science (PLoS)","issue":"6","license":[{"start":{"date-parts":[[2023,6,23]],"date-time":"2023-06-23T00:00:00Z","timestamp":1687478400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100006578","name":"Chi Mei Medical Center","doi-asserted-by":"publisher","award":["Grant Physician-Scientist 11001"],"award-info":[{"award-number":["Grant Physician-Scientist 11001"]}],"id":[{"id":"10.13039\/501100006578","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\">\n<jats:title>Background<\/jats:title>\n<jats:p>Dentists may be at a higher risk of developing carpal tunnel syndrome (CTS) because of their use of frequent wrist and vibratory instruments at work; however, this issue remains unclear. Therefore, we conducted this study to clarify it.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec002\">\n<jats:title>Methods<\/jats:title>\n<jats:p>Taiwan National Health Insurance Research Database was used for this nationwide population-based study. We identified 11,084 dentists, 74,901 non-dentist healthcare professionals (HCPs), and identical number of age- and sex-matched participants from the general population. Participants who had the diagnosis of CTS before 2007 were excluded. Between 2007 and 2011, the risk of developing CTS among dentists, non-dentist HCPs, and the general population was compared by following their medical histories.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec003\">\n<jats:title>Results<\/jats:title>\n<jats:p>The cumulative incidence rate of CTS among dentists was 0.5% during the 5-year follow-up period. In dentists, the risk was higher in women (women: 0.7%; men: 0.4%) and older individuals (\u226560 years: 1.0%; &lt;60 years: 0.4%). After adjusting for age, sex, and underlying comorbidities, dentists had a lower risk of CTS than the general population (adjusted odds ratio [AOR]: 0.65, 95% confidence interval [CI]: 0.45\u20130.92). Dentists had a higher risk for CTS compared with non-dentist HCPs, although the difference was not statistically significant (AOR: 1.21; 95% CI: 0.90\u22121.64).<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec004\">\n<jats:title>Conclusions<\/jats:title>\n<jats:p>In CTS, dentists had a lower risk than the general population and a trend of higher risk than non-dentist HCPs. The difference between dentists and non-dentist HCPs suggests that we should pay attention to dentists for potential occupational risk of this disease. However, further studies are warranted to better clarify it.<\/jats:p>\n<\/jats:sec>","DOI":"10.1371\/journal.pone.0287351","type":"journal-article","created":{"date-parts":[[2023,6,24]],"date-time":"2023-06-24T23:15:11Z","timestamp":1687648511000},"page":"e0287351","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":2,"title":["Carpal tunnel syndrome in dentists compared to other populations: A nationwide population-based study in Taiwan"],"prefix":"10.1371","volume":"18","author":[{"given":"Wei-Ta","family":"Huang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chia-Ti","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chung-Han","family":"Ho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi-Chen","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu-Chieh","family":"Ho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chien-Chin","family":"Hsu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hung-Jung","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jhi-Joung","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lian-Ping","family":"Mau","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3595-2952","authenticated-orcid":true,"given":"Chien-Cheng","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2023,6,23]]},"reference":[{"key":"pone.0287351.ref001","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1001\/jama.282.2.153","article-title":"Prevalence of carpal tunnel syndrome in a general population","volume":"282","author":"I Atroshi","year":"1999","journal-title":"JAMA"},{"key":"pone.0287351.ref002","first-page":"952","article-title":"Carpal tunnel syndrome","volume":"83","author":"KE LeBlanc","year":"2011","journal-title":"Am Fam Physician"},{"key":"pone.0287351.ref003","article-title":"Occupational risk factors for work disability following carpal tunnel syndrome: a pooled prospective study","author":"C Harris-Adamson","year":"2022","journal-title":"Occup Environ Med"},{"key":"pone.0287351.ref004","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.berh.2011.01.014","article-title":"Carpal tunnel syndrome: the role of occupational factors","volume":"25","author":"KT Palmer","year":"2011","journal-title":"Best Pract Res Clin Rheumatol"},{"key":"pone.0287351.ref005","doi-asserted-by":"crossref","first-page":"30","DOI":"10.5005\/jp-journals-10005-1229","article-title":"Ergonomics in dentistry","volume":"7","author":"A Gupta","year":"2014","journal-title":"Int J Clin Pediatr Dent"},{"key":"pone.0287351.ref006","doi-asserted-by":"crossref","first-page":"163","DOI":"10.14219\/jada.archive.2001.0150","article-title":"Prevalence of carpal tunnel syndrome and median mononeuropathy among dentists","volume":"132","author":"C Hamann","year":"2001","journal-title":"J Am Dent Assoc"},{"key":"pone.0287351.ref007","doi-asserted-by":"crossref","first-page":"13","DOI":"10.4103\/2277-9175.96069","article-title":"Prevalence of clinical findings of carpal tunnel syndrome in Isfahanian dentists","volume":"1","author":"A Haghighat","year":"2012","journal-title":"Adv Biomed Res"},{"key":"pone.0287351.ref008","doi-asserted-by":"crossref","first-page":"104","DOI":"10.5144\/0256-4947.2019.07.03.1405","article-title":"Prevalence of carpal tunnel syndrome symptoms among dentists working in Riyadh","volume":"39","author":"FA Alhusain","year":"2019","journal-title":"Ann Saudi Med"},{"key":"pone.0287351.ref009","first-page":"349","article-title":"Taiwan\u2019s National Health Insurance Research Database: past and future","volume":"11","author":"CY Hsieh","year":"2019"},{"key":"pone.0287351.ref010","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1016\/S1474-4422(16)30231-9","article-title":"Carpal tunnel syndrome: clinical features, diagnosis, and management","volume":"15","author":"L Padua","year":"2016","journal-title":"Lancet Neurol"},{"key":"pone.0287351.ref011","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1186\/s12891-019-2559-3","article-title":"Risk for cervical herniated intervertebral disc in dentists: a nationwide population-based study","volume":"20","author":"CC Huang","year":"2019","journal-title":"BMC Musculoskelet Disord"},{"key":"pone.0287351.ref012","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1002\/1348-9585.12036","article-title":"Comparison of the risk of developing lumbar herniated intervertebral disc 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antibiotics","volume":"2","author":"MK Shubha RS","year":"2013","journal-title":"Journal of Evolution of Medical and Dental Sciences"},{"key":"pone.0287351.ref016","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1111\/idj.12037","article-title":"Carpal tunnel syndrome\u2014an occupational hazard facing dentistry","volume":"63","author":"S Abichandani","year":"2013","journal-title":"Int Dent J"},{"key":"pone.0287351.ref017","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1097\/SAP.0000000000002950","article-title":"Risk Factors of Carpal Tunnel Syndrome in Taiwan: A Population-Based Cohort Study","volume":"88","author":"C Yang","year":"2022","journal-title":"Ann Plast Surg"},{"key":"pone.0287351.ref018","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1177\/1753193408090142","article-title":"Carpal tunnel syndrome: a case-control study evaluating its relationship with body mass index and hand and wrist measurements","volume":"33","author":"JE Farmer","year":"2008","journal-title":"J Hand Surg Eur"},{"key":"pone.0287351.ref019","first-page":"305","article-title":"Histo-mechanical aspects of carpal tunnel syndrome","volume":"15","author":"R Lin","year":"1983","journal-title":"Hand"},{"key":"pone.0287351.ref020","first-page":"e23876","article-title":"Prevalence of First Carpometacarpal Joint Osteoarthritis and Carpal Tunnel Syndrome Among Dentists in Saudi Arabia","volume":"14","author":"H AlKhodier","year":"2022","journal-title":"Cureus"},{"key":"pone.0287351.ref021","unstructured":"Statistical Table of Public Health Affairs: Taiwan Ministry of Health and Welfare, 2023."},{"key":"pone.0287351.ref022","unstructured":"Population statistics data: Department of Househeld Registration, 2023."}],"container-title":["PLOS 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