{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T12:23:41Z","timestamp":1785155021654,"version":"3.55.0"},"reference-count":60,"publisher":"Public Library of Science (PLoS)","issue":"8","license":[{"start":{"date-parts":[[2023,8,2]],"date-time":"2023-08-02T00:00:00Z","timestamp":1690934400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:sec id=\"sec001\">\n<jats:title>Background<\/jats:title>\n<jats:p>The life quality of about two-thirds of patients with COVID-19 is affected by related olfactory dysfunctions. The negative impact of olfactory dysfunction ranged from the decreased pleasure of eating to impaired quality of life. This research aimed to provide a comprehensive understanding of the effects of corticosteroid treatments by comparing that to other currently available treatments and interventions.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec002\">\n<jats:title>Methods<\/jats:title>\n<jats:p>The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) checklist\u2019s 27-point checklist was used to conduct this review. PubMed (Public\/Publisher MEDLINE), PubMed Central and EMBASE (Excerpta Medica Database) databases were conveniently selected and Boolean search commands were used for a comprehensive literature search. Five core search terms were \"effects of treatments\", \" COVID-19-related olfactory dysfunction\", \"corticosteroids\", \"treatments\" and \"interventions\". The reporting qualities of the included studies were appraised using JBI (Joanna Briggs Institute) appraisal tools. The characteristics of the 21 experimental studies with a total sample (of 130,550) were aggregated using frequencies and percentages and presented descriptively. The main interventions and their effects on the duration of the COVID-19-related olfactory dysfunction were narratively analyzed.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec003\">\n<jats:title>Results<\/jats:title>\n<jats:p>Among patients with COVID-19, the normal functions of the olfactory lobe were about 23 days earlier to gain with the treatments of fluticasone and triamcinolone acetonide nasal spray compared with that of mometasone furoate nasal spray and oral corticosteroid. The smell loss duration was reduced by fluticasone and triamcinolone acetonide nasal spray 9 days earlier than the inflawell syrup and 16 days earlier than the lavender syrup. The nasal spray of corticosteroids ended the COVID-19-related smell loss symptoms 2 days earlier than the zinc supplementation, about 47 days earlier than carbamazepine treatment and was more effective than palmitoylethanolamide (PEA) and luteolin and omega-3 supplementations and olfactory training. Treatment with oral corticosteroid plus olfactory training significantly improved Threshold, Discrimination and Identification (TDI) scores compared with olfactory training alone. A full dose of the COVID-19 vaccination was not uncertain to reduce the COVID-19-related smell loss duration.<\/jats:p>\n<\/jats:sec>\n<jats:sec id=\"sec004\">\n<jats:title>Conclusion<\/jats:title>\n<jats:p>Corticosteroid treatment is effective in reducing the duration of COVID-19-related smell loss and olfactory training, the basic, essential and effective intervention, should be used as a combination therapy.<\/jats:p>\n<\/jats:sec>","DOI":"10.1371\/journal.pone.0288285","type":"journal-article","created":{"date-parts":[[2023,8,2]],"date-time":"2023-08-02T17:25:39Z","timestamp":1690997139000},"page":"e0288285","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":6,"title":["Effect of any form of steroids in comparison with that of other medications on the duration of olfactory dysfunction in patients with COVID-19: A systematic review of randomized trials and quasi-experimental studies"],"prefix":"10.1371","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2604-3431","authenticated-orcid":true,"given":"Phyo Zin","family":"Winn","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thein","family":"Hlaing","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyaw Myo","family":"Tun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seim Lei","family":"Lei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2023,8,2]]},"reference":[{"key":"pone.0288285.ref001","doi-asserted-by":"crossref","first-page":"3544","DOI":"10.3390\/ijms21103544","article-title":"The role of lipid metabolism in Covid-19 virus infection and as a drug target","volume":"21","author":"M Abu.Farha","year":"2020","journal-title":"Int. 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Available at: <https:\/\/www.healthline.com\/health\/anosmia> [Accessed 3 March 2022]."},{"key":"pone.0288285.ref006","unstructured":"Seladi-Schulman J. Parosmia After COVID-19: Causes, Duration, Treatment & More. 2021. [online] Healthline. Available at: <https:\/\/www.healthline.com\/health\/parosmia-after-covid> [Accessed 3 March 2022]."},{"issue":"9","key":"pone.0288285.ref007","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1093\/chemse\/bjaa066","article-title":"Gaining Back What Is Lost: Recovering the Sense of Smell in Mild to Moderate Patients After COVID-19","volume":"45","author":"Lucia Iannuzzi","year":"2020","journal-title":"Chemical Senses"},{"issue":"3","key":"pone.0288285.ref008","doi-asserted-by":"crossref","first-page":"e33365","DOI":"10.1371\/journal.pone.0033365","article-title":"Learning about the functions of the olfactory system from people without a sense of smell","volume":"7","author":"I Croy","journal-title":"PLoS One. 2012"},{"key":"pone.0288285.ref009","doi-asserted-by":"crossref","first-page":"101317","DOI":"10.1016\/j.eclinm.2022.101317","article-title":"Variation in global COVID-19 symptoms by geography and by chronic disease: A global survey using the COVID-19 Symptom 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Morrissey","year":"2016","journal-title":"Laryngoscope"},{"issue":"2","key":"pone.0288285.ref031","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1177\/0194599820943550","article-title":"Olfactory Training for Postviral Olfactory Dysfunction: Systematic Review and Meta-analysis","volume":"164","author":"N Kattar","year":"2021","journal-title":"Otolaryngol Head Neck Surg"},{"issue":"2","key":"pone.0288285.ref032","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.iac.2019.12.013","article-title":"Olfactory Dysfunction and Chronic Rhinosinusitis","volume":"40","author":"OG Ahmed","year":"2020","journal-title":"Immunol Allergy Clin North Am"},{"issue":"4","key":"pone.0288285.ref033","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.3122\/jabfm.2021.06.210254","article-title":"Addressing post-COVID symptoms: A guide for primary care physicians","volume":"36","author":"H Vance","year":"2021","journal-title":"Journal of the American Board of Family 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