{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T04:20:48Z","timestamp":1747196448027,"version":"3.40.5"},"reference-count":65,"publisher":"Public Library of Science (PLoS)","issue":"8","license":[{"start":{"date-parts":[[2023,8,17]],"date-time":"2023-08-17T00:00:00Z","timestamp":1692230400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"NIH-NIGMS","award":["T32-GM081740"],"award-info":[{"award-number":["T32-GM081740"]}]}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:p>Low back pain is associated with changes in trunk muscle structure and function and motor control impairments. Voluntary force modulation (FM) of trunk muscles is a unique and under-investigated motor control characteristic. One of the reasons for this paucity of evidence is the lack of exploration and publication on the reliability and validity of trunk FM protocols. The purpose of this study was to determine the within- and between-day test-retest reliability and construct validity for trunk extensor muscle FM. Twenty-nine healthy participants were tested under three FM conditions with different modulation rates. Testing was performed on a custom-built apparatus designed for trunk isometric force testing. FM accuracy relative to a fluctuating target force (20\u201350%MVF) was quantified using the root mean square error of the participant\u2019s generated force relative to the target force. Reliability and precision of measurement were assessed using the Intraclass Correlation Coefficient (ICC), standard error of measurement (SEM), minimal detectable difference (MDD<jats:sub>95<\/jats:sub>), and Bland-Altman plots. In a subset of participants, we collected surface electromyography of trunk and hip muscles. We used non-negative matrix factorization (NNMF) to identify the underlying motor control strategies. Within- and between-day test-retest reliability was excellent for FM accuracy across the three conditions (ICC range: 0.865 to 0.979). SEM values ranged 0.9\u20131.8 Newtons(N) and MDD<jats:sub>95<\/jats:sub> ranged from 2.4\u20134.9N. Conditions with faster rates of FM had higher ICCs. NNMF analysis revealed two muscle synergies that were consistent across participants and conditions. These synergies demonstrate that the muscles primarily involved in this FM task were indeed the trunk extensor muscles. This protocol can consistently measure FM accuracy within and between testing sessions. Trunk extensor FM, as measured by this protocol, is not specific to any trunk muscle group but is the result of modulation by all the trunk extensor muscles.<\/jats:p>","DOI":"10.1371\/journal.pone.0289531","type":"journal-article","created":{"date-parts":[[2023,8,17]],"date-time":"2023-08-17T17:40:14Z","timestamp":1692294014000},"page":"e0289531","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":1,"title":["Test-retest reliability and construct validity of trunk extensor muscle force modulation accuracy"],"prefix":"10.1371","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2207-7610","authenticated-orcid":true,"given":"John R.","family":"Gilliam","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahyoung","family":"Song","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pradeep 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European Recommendations for Surface Electro-myography.1999."},{"issue":"5","key":"pone.0289531.ref046","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1136\/bjsm.33.5.336","article-title":"Reliability of ratings of perceived exertion during progressive treadmill exercise","volume":"33","author":"KL Lamb","year":"1999","journal-title":"Br J Sports Med"},{"issue":"2","key":"pone.0289531.ref047","doi-asserted-by":"crossref","DOI":"10.1249\/00005768-197300520-00018","article-title":"The validity and reliability of a rating scale of perceived exertion","volume":"5","author":"JS Skinner","year":"1973","journal-title":"Medicine & Science in Sports & Exercise"},{"key":"pone.0289531.ref048","unstructured":"Cannella M S S. Automatic procedure to remove ECG from trunkmuscle sEMG using independent components analysis (Abstract). 2010;Los Angeles,CA, November 9\u201312:536\u20137."},{"issue":"3","key":"pone.0289531.ref049","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1016\/j.jelekin.2012.01.001","article-title":"Removing ECG contamination from EMG recordings: A comparison of ICA-based and other filtering procedures","volume":"22","author":"NW Willigenburg","year":"2012","journal-title":"Journal of Electromyography and Kinesiology"},{"issue":"30","key":"pone.0289531.ref050","doi-asserted-by":"crossref","first-page":"7791","DOI":"10.1523\/JNEUROSCI.0830-06.2006","article-title":"Control of Fast-Reaching Movements by Muscle Synergy Combinations","volume":"26","author":"A d\u2019Avella","year":"2006","journal-title":"The Journal of Neuroscience"},{"issue":"27","key":"pone.0289531.ref051","doi-asserted-by":"crossref","first-page":"6419","DOI":"10.1523\/JNEUROSCI.4904-04.2005","article-title":"Central and Sensory Contributions to the Activation and Organization of Muscle Synergies during Natural Motor Behaviors","volume":"25","author":"VCK Cheung","year":"2005","journal-title":"The Journal of Neuroscience"},{"issue":"2","key":"pone.0289531.ref052","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.jcm.2016.02.012","article-title":"A Guideline of Selecting and Reporting Intraclass Correlation Coefficients for Reliability Research","volume":"15","author":"TK Koo","year":"2016","journal-title":"J Chiropr Med"},{"volume-title":"Design and analysis of clinical experiments","year":"2011","author":"JL Fleiss","key":"pone.0289531.ref053"},{"issue":"8476","key":"pone.0289531.ref054","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/S0140-6736(86)90837-8","article-title":"Statistical methods for assessing agreement between two methods of clinical measurement","volume":"1","author":"JM Bland","year":"1986","journal-title":"Lancet"},{"key":"pone.0289531.ref055","doi-asserted-by":"crossref","DOI":"10.3389\/fpsyg.2013.00863","article-title":"Calculating and reporting effect sizes to facilitate cumulative science: a practical primer for t-tests and ANOVAs","volume":"4","author":"D Lakens","year":"2013","journal-title":"Frontiers in Psychology"},{"issue":"1","key":"pone.0289531.ref056","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1007\/s00421-009-0994-9","article-title":"Activation amplitude patterns do not change for back muscles but are altered for abdominal muscles between dominant and non-dominant hands during one-handed lifts","volume":"106","author":"HL Butler","year":"2009","journal-title":"Eur J Appl Physiol"},{"key":"pone.0289531.ref057","unstructured":"Tang L, Li F, Cao S, Zhang X, Chen X, editors. 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