{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,9]],"date-time":"2026-05-09T13:47:42Z","timestamp":1778334462276,"version":"3.51.4"},"reference-count":47,"publisher":"Public Library of Science (PLoS)","issue":"8","license":[{"start":{"date-parts":[[2024,8,19]],"date-time":"2024-08-19T00:00:00Z","timestamp":1724025600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"abstract":"<jats:p>Among adolescents, HIV\/AIDs remains a significant cause of death globally [1\u20134]. Given the unique stages in human development, adolescents have been shown to fall within a sexually active phase. Combined with other social and structural factors in their immediate environments, HIV prevention and care among adolescents can be filled with challenges for intervention. This paper outlines this protocol to systematically review peer-reviewed literature in prevention and care among adolescents 10\u201319 years. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) will be used to report this scoping review. The review will involve screening and extracting data using covidence as the primary tool. The review will encompass quantitative, qualitative, and mixed methods studies, utilizing a search strategy from electronic databases such as PubMed (NCBI), Web of Science Core Collection (Clarivate), Embase (Elsevier), and Scopus (Elsevier). Additionally, a search will be conducted for grey literature using Global Index Medicus (WHO), MedNar (Deep Web Technologies), and Central Register of Controlled Trials (Cochrane). Duplicate removal and selection of articles that meet the inclusion criteria for the study will be performed using Covidence. Once the screening process is complete, data will be extracted from the full-text screened articles in Covidence. We will pilot the extracted data in Covidence to ensure that all relevant information has been captured, making necessary changes if required. Data extraction will be carried out by at least two authors, with any conflicts resolved by the same authors. If a conflict cannot be resolved between the two, a third author will make a final determination. We aim to analyze data thematically by employing a grounded theory approach to generate codes pertinent to the research question. The team will review and discuss codes to create a cohesive set of codes that will be instrumental in identifying knowledge gaps and constructing themes that summarize the data. The proposed systematic review will be among the pioneering efforts to rigorously assess global data on HIV prevention and care, with a specific focus on adolescents 10\u201319 years. It will consider the diverse socio-economic factors and experiences shaping these adolescents\u2019 lives in HIV prevention and care. We expect this review to yield critical insights into the present landscape of HIV prevention and care for individuals aged 10\u201319. These findings will also play a pivotal role in shaping the development of a global framework that researchers and stakeholders can readily adopt and implement across socio-economic contexts. This framework will aim to address the unique needs of all adolescents concerning HIV prevention and care.<\/jats:p>","DOI":"10.1371\/journal.pone.0289994","type":"journal-article","created":{"date-parts":[[2024,8,19]],"date-time":"2024-08-19T17:30:36Z","timestamp":1724088636000},"page":"e0289994","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":7,"title":["Adolescent HIV prevent and care framework: A global scoping review protocol- BSGH 006"],"prefix":"10.1371","volume":"19","author":[{"given":"Gamji Rabiu","family":"Abu-Ba\u2019are","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3127-9596","authenticated-orcid":true,"given":"Osman Wumpini","family":"Shamrock","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Darcey","family":"Rodriguez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George Rudolph Kofi","family":"Agbemedu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"LaRon E.","family":"Nelson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2024,8,19]]},"reference":[{"issue":"1","key":"pone.0289994.ref001","article-title":"Long-term trends in mortality and AIDS-defining events after combination ART initiation among children and adolescents with perinatal HIV infection in 17 middle- and high-income countries in Europe and Thailand: A cohort study.","volume":"15","author":"A Judd","year":"2018","journal-title":"PLoS Med."},{"issue":"2","key":"pone.0289994.ref002","doi-asserted-by":"crossref","DOI":"10.1002\/jia2.25886","article-title":"Predictors of mortality among adolescents and young adults living with HIV on antiretroviral therapy in Dar es Salaam, Tanzania: a retrospective cohort study.","volume":"25","author":"MA Amour","year":"2022","journal-title":"J Int AIDS Soc"},{"issue":"10","key":"pone.0289994.ref003","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0223655","article-title":"Adolescents living with HIV are at higher risk of death and loss to follow up from care: Analysis of cohort data from eight health facilities in Ethiopia.","volume":"14","author":"D Jerene","year":"2019","journal-title":"PLoS One."},{"key":"pone.0289994.ref004","volume-title":"Although strides have been made in the HIV response, children are still affected by the epidemic.","author":"UNICEF","year":"2021"},{"key":"pone.0289994.ref005","volume-title":"The top 10 causes of death\u2014Factsheet.","author":"WHO","year":"2020"},{"issue":"Supplement 2","key":"pone.0289994.ref006","doi-asserted-by":"crossref","first-page":"S213","DOI":"10.1097\/QAI.0b013e3182986f3a","article-title":"Integrated Strategies for Combination HIV Prevention.","volume":"63","author":"C Celum","year":"2013","journal-title":"JAIDS Journal of Acquired Immune Deficiency Syndromes"},{"issue":"8","key":"pone.0289994.ref007","doi-asserted-by":"crossref","DOI":"10.1097\/OLQ.0000000000001374","article-title":"Rural College Students\u2019 Amenability Toward Using At-Home Human Immunodeficiency Virus and Sexually Transmitted Infection Testing Kits.","volume":"48","author":"RD Hubach","year":"2021","journal-title":"Sex Transm Dis."},{"issue":"12","key":"pone.0289994.ref008","doi-asserted-by":"crossref","DOI":"10.1136\/bmjgh-2021-007212","article-title":"Roll-out of HIV pre-exposure prophylaxis: A gateway to mental health promotion","volume":"6","author":"DJ Ikeda","year":"2021","journal-title":"BMJ Glob Health"},{"issue":"1","key":"pone.0289994.ref009","article-title":"Point of care diagnostics for HIV in resource limited settings: An overview.","volume":"5454","author":"SL Manoto","year":"2018","journal-title":"Medicina (Lithuania)."},{"key":"pone.0289994.ref010","doi-asserted-by":"crossref","DOI":"10.1155\/2018\/3750646","article-title":"Lectins as promising therapeutics for the prevention and treatment of HIV and other potential coinfections.","volume":"2018","author":"M Mazalovska","year":"2018","journal-title":"BioMed Research International"},{"issue":"3","key":"pone.0289994.ref011","doi-asserted-by":"crossref","first-page":"296","DOI":"10.2991\/jegh.k.210621.001","article-title":"Global Epidemiology of HIV\/AIDS: A Resurgence in North America and Europe","volume":"11","author":"R. 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